| MeSH term | MeSH ID | Detail |
|---|---|---|
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jobichen C et al. | Identification and characterization of the lipid-binding property of GrlR, a locus of enterocyte effacement regulator. | 2009 | Biochem. J. | pmid:19228114 |
| Schuiki I and Daum G | Phosphatidylserine decarboxylases, key enzymes of lipid metabolism. | 2009 | IUBMB Life | pmid:19165886 |
| Wriessnegger T et al. | Lipid analysis of mitochondrial membranes from the yeast Pichia pastoris. | 2009 | Biochim. Biophys. Acta | pmid:19168151 |
| Zivkovic AM et al. | Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease. | 2009 | Alcohol. Clin. Exp. Res. | pmid:19170661 |
| Rezanka T et al. | Very-long-chain iso and anteiso branched fatty acids in N-acylphosphatidylethanolamines from a natural cyanobacterial mat of Calothrix sp. | 2009 | Phytochemistry | pmid:19272619 |
| Arouri A et al. | Peptide induced demixing in PG/PE lipid mixtures: a mechanism for the specificity of antimicrobial peptides towards bacterial membranes? | 2009 | Biochim. Biophys. Acta | pmid:19118516 |
| Sawant RR and Torchilin VP | Enhanced cytotoxicity of TATp-bearing paclitaxel-loaded micelles in vitro and in vivo. | 2009 | Int J Pharm | pmid:19446767 |
| Nivon M et al. | Autophagy activation by NFkappaB is essential for cell survival after heat shock. | 2009 | Autophagy | pmid:19502777 |
| Gibellini F et al. | The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei. | 2009 | Mol. Microbiol. | pmid:19555461 |
| Rosenberger S et al. | Phosphatidylethanolamine synthesized by three different pathways is supplied to peroxisomes of the yeast Saccharomyces cerevisiae. | 2009 | Biochim. Biophys. Acta | pmid:19830909 |
| Hon GM et al. | Red blood cell membrane fluidity in the etiology of multiple sclerosis. | 2009 | J. Membr. Biol. | pmid:19915887 |
| Dennison SR et al. | A study on the importance of phenylalanine for aurein functionality. | 2009 | Protein Pept. Lett. | pmid:20001908 |
| Schober C et al. | Lysophosphatidylethanolamine is - in contrast to - choline - generated under in vivo conditions exclusively by phospholipase A2 but not by hypochlorous acid. | 2009 | Bioorg. Chem. | pmid:19818468 |
| Kotlova ER et al. | [Changes of membrane glycerolipids and sphingolipids during Flammulina velutipes surface growth]. | 2009 Mar-Apr | Mikrobiologiia | pmid:19449736 |
| Koynova R et al. | Hydrophobic moiety of cationic lipids strongly modulates their transfection activity. | 2009 May-Jun | Mol. Pharm. | pmid:19341312 |
| Lefils J et al. | Dietary DHA: time course of tissue uptake and effects on cytokine secretion in mice. | 2010 | Br. J. Nutr. | pmid:20487585 |
| Sa'adedin F and Bradshaw JP | A differential scanning calorimetry study of the effects and interactions of antimicrobial peptide LS3 on phosphatidylethanolamine bilayers. | 2010 | Protein Pept. Lett. | pmid:20673229 |
| Bogdanov M et al. | Plasticity of lipid-protein interactions in the function and topogenesis of the membrane protein lactose permease from Escherichia coli. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20696931 |
| Karatsa-Dodgson M et al. | In vitro analysis of the Staphylococcus aureus lipoteichoic acid synthase enzyme using fluorescently labeled lipids. | 2010 | J. Bacteriol. | pmid:20709894 |
| GarcÃa-Arcos I et al. | Lipid analysis reveals quiescent and regenerating liver-specific populations of lipid droplets. | 2010 | Lipids | pmid:21063798 |
| Sun M et al. | Octreotide-modification enhances the delivery and targeting of doxorubicin-loaded liposomes to somatostatin receptors expressing tumor in vitro and in vivo. | 2010 | Nanotechnology | pmid:21030757 |
| Lucena T et al. | Euzebyella saccharophila gen. nov., sp. nov., a marine bacterium of the family Flavobacteriaceae. | 2010 | Int. J. Syst. Evol. Microbiol. | pmid:20081010 |
| Rudra A et al. | Doxorubicin-loaded phosphatidylethanolamine-conjugated nanoliposomes: in vitro characterization and their accumulation in liver, kidneys, and lungs in rats. | 2010 | Int J Nanomedicine | pmid:21042545 |
| Morgan AH et al. | Quantitative assays for esterified oxylipins generated by immune cells. | 2010 | Nat Protoc | pmid:21127486 |
| Sapay N et al. | Molecular simulations of lipid flip-flop in the presence of model transmembrane helices. | 2010 | Biochemistry | pmid:20666375 |
| Saito H and Marty Y | High levels of icosapentaenoic acid in the lipids of oyster Crassostrea gigas ranging over both Japan and France. | 2010 | J Oleo Sci | pmid:20484833 |
| Rambold AS and Lippincott-Schwartz J | Starved cells use mitochondria for autophagosome biogenesis. | 2010 | Cell Cycle | pmid:20855967 |
| Leventis R and Silvius JR | Quantitative experimental assessment of macromolecular crowding effects at membrane surfaces. | 2010 | Biophys. J. | pmid:20923646 |
| Sawant RR and Torchilin VP | Multifunctionality of lipid-core micelles for drug delivery and tumour targeting. | 2010 | Mol. Membr. Biol. | pmid:20929339 |
| Rzeźnicka II et al. | Duramycin-induced destabilization of a phosphatidylethanolamine monolayer at the air-water interface observed by vibrational sum-frequency generation spectroscopy. | 2010 | Langmuir | pmid:20873825 |
| Wu B et al. | [In vivo replacement of phosphatidylethanolamine by phosphatidylcholine affects biological function of E. coli]. | 2010 | Wei Sheng Wu Xue Bao | pmid:21268895 |
| Kao PH et al. | Guanidination of notexin alters its membrane-damaging activity in response to sphingomyelin and cholesterol. | 2010 | J. Biosci. | pmid:21289441 |
| Maniti O et al. | Distinct behaviour of the homeodomain derived cell penetrating peptide penetratin in interaction with different phospholipids. | 2010 | PLoS ONE | pmid:21209890 |
| SolÃs-Calero C et al. | Reactivity of a phospholipid monolayer model under periodic boundary conditions: a density functional theory study of the Schiff base formation between phosphatidylethanolamine and acetaldehyde. | 2010 | J Phys Chem B | pmid:21077587 |
| Wang J et al. | [Infection with hepatitis B virus enhances basal autophagy]. | 2010 | Wei Sheng Wu Xue Bao | pmid:21365919 |
| Ecker J et al. | Differential effects of conjugated linoleic acid isomers on macrophage glycerophospholipid metabolism. | 2010 | J. Lipid Res. | pmid:20522602 |
| Yamamoto M et al. | Novel polysaccharide-derived hydrogel prevents perineural adhesions in a rat model of sciatic nerve adhesion. | 2010 | J. Orthop. Res. | pmid:19780191 |
| Gabrys CM et al. | Nuclear magnetic resonance evidence for retention of a lamellar membrane phase with curvature in the presence of large quantities of the HIV fusion peptide. | 2010 | Biochim. Biophys. Acta | pmid:19616505 |
| Behzadi M et al. | A model of phospholipid biosynthesis in tumor in response to an anticancer agent in vivo. | 2010 | J Integr Bioinform | pmid:20375456 |
| Gustot A et al. | Lipid composition regulates the orientation of transmembrane helices in HorA, an ABC multidrug transporter. | 2010 | J. Biol. Chem. | pmid:20223819 |
| Matonti F et al. | [Central retinal vein occlusion and anti-phosphatidylethanolamine antibodies isolation: a case report]. | 2010 | Can. J. Ophthalmol. | pmid:20379283 |
| Kliman M et al. | Structural mass spectrometry analysis of lipid changes in a Drosophila epilepsy model brain. | 2010 | Mol Biosyst | pmid:20379606 |
| Sanmarco M | ELISA for antiphosphatidylethanolamine antibody detection: high impact of assay buffer on results. | 2010 | J. Immunol. Methods | pmid:20382150 |
| Shoji N et al. | LC-MS/MS analysis of carboxymethylated and carboxyethylated phosphatidylethanolamines in human erythrocytes and blood plasma. | 2010 | J. Lipid Res. | pmid:20386060 |
| van Uitert I et al. | The influence of different membrane components on the electrical stability of bilayer lipid membranes. | 2010 | Biochim. Biophys. Acta | pmid:19835838 |
| Dannenberger D et al. | The intact muscle lipid composition of bulls: an investigation by MALDI-TOF MS and 31P NMR. | 2010 | Chem. Phys. Lipids | pmid:19900429 |
| Reich A et al. | Lipidome of narrow-band ultraviolet B irradiated keratinocytes shows apoptotic hallmarks. | 2010 | Exp. Dermatol. | pmid:19845761 |
| Marsh D | Structural and thermodynamic determinants of chain-melting transition temperatures for phospholipid and glycolipids membranes. | 2010 | Biochim. Biophys. Acta | pmid:19853577 |
| Ibarguren M et al. | End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa. | 2010 | Biochim. Biophys. Acta | pmid:19891956 |
| Zavaleta-Pastor M et al. | Sinorhizobium meliloti phospholipase C required for lipid remodeling during phosphorus limitation. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20018679 |
| Sutoh K et al. | Specific induction of TaAAPT1, an ER- and Golgi-localized ECPT-type aminoalcoholphosphotransferase, results in preferential accumulation of the phosphatidylethanolamine membrane phospholipid during cold acclimation in wheat. | 2010 | Plant Mol. Biol. | pmid:20024669 |
| Xiao S et al. | Overexpression of Arabidopsis acyl-CoA binding protein ACBP3 promotes starvation-induced and age-dependent leaf senescence. | 2010 | Plant Cell | pmid:20442372 |
| Obayashi S et al. | Antiphosphatidylethanolamine antibodies might not be an independent risk factor for further miscarriage in patients suffering recurrent pregnancy loss. | 2010 | J. Reprod. Immunol. | pmid:20462639 |
| Campodonico EM and Zusman DR | Developments in Defining dif. | 2010 | J. Bacteriol. | pmid:20601469 |
| Richmond GS et al. | Lipidomic analysis of bloodstream and procyclic form Trypanosoma brucei. | 2010 | Parasitology | pmid:20602846 |
| Yamaguchi M et al. | Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway. | 2010 | J. Biol. Chem. | pmid:20615880 |
| Lanekoff I et al. | Time of flight mass spectrometry imaging of samples fractured in situ with a spring-loaded trap system. | 2010 | Anal. Chem. | pmid:20593800 |
| Weidberg H et al. | LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. | 2010 | EMBO J. | pmid:20418806 |
| Kosinets VA et al. | [Effect of reamberin on the lipid spectrum of the liver mitochondria in experimental widespread purulent peritonitis]. | 2010 | Eksp Klin Farmakol | pmid:20408428 |
| Wang T et al. | Paclitaxel-loaded polymeric micelles modified with MCF-7 cell-specific phage protein: enhanced binding to target cancer cells and increased cytotoxicity. | 2010 | Mol. Pharm. | pmid:20518562 |
| Girardi E et al. | Crystal structure of bovine CD1b3 with endogenously bound ligands. | 2010 | J. Immunol. | pmid:20519644 |
| Ibarguren M et al. | Quantitation of cholesterol incorporation into extruded lipid bilayers. | 2010 | Biochim. Biophys. Acta | pmid:20537979 |
| Aoyama C | [Function of choline kinase]. | 2010 | Seikagaku | pmid:20496749 |
| Gibellini F and Smith TK | The Kennedy pathway--De novo synthesis of phosphatidylethanolamine and phosphatidylcholine. | 2010 | IUBMB Life | pmid:20503434 |
| Deng L et al. | Incorporation and remodeling of phosphatidylethanolamine containing short acyl residues in yeast. | 2010 | Biochim. Biophys. Acta | pmid:20176132 |
| Chen YL et al. | Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans. | 2010 | Mol. Microbiol. | pmid:20132453 |
| Tsuji A and Yoshikawa K | Real-time monitoring of RNA synthesis in a phospholipid-coated microdroplet as a live-cell model. | 2010 | Chembiochem | pmid:20058251 |
| Kale AA and Torchilin VP | Environment-responsive multifunctional liposomes. | 2010 | Methods Mol. Biol. | pmid:20072884 |
| Sullivan CB et al. | Isoketals form cytotoxic phosphatidylethanolamine adducts in cells. | 2010 | J. Lipid Res. | pmid:19965577 |
| Cordomà A et al. | Interactions of fatty acids with phosphatidylethanolamine membranes: X-ray diffraction and molecular dynamics studies. | 2010 | J. Lipid Res. | pmid:19965616 |
| Bogdanov M et al. | Study of polytopic membrane protein topological organization as a function of membrane lipid composition. | 2010 | Methods Mol. Biol. | pmid:20419405 |
| Lau BY et al. | Fat-1 gene modulates the fatty acid composition of femoral and vertebral phospholipids. | 2010 | Appl Physiol Nutr Metab | pmid:20725110 |
| Athamena A et al. | Synthesis of phosphatidylcholine through phosphatidylethanolamine N-methylation in tissues of the mussel Mytilus galloprovincialis. | 2011 | Lipids | pmid:21769692 |
| Zhao S et al. | [Metabonomics and phospholipid metabolic profiling of abnormal glucose metabolism based on high performance liquid chromatography-electrospray mass spectrometry]. | 2011 | Se Pu | pmid:21770239 |
| Nair U et al. | SNARE proteins are required for macroautophagy. | 2011 | Cell | pmid:21784249 |
| Biswas S et al. | Development of the novel PEG-PE-based polymer for the reversible attachment of specific ligands to liposomes: synthesis and in vitro characterization. | 2011 | Bioconjug. Chem. | pmid:21870873 |
| O'Donnell VB | Mass spectrometry analysis of oxidized phosphatidylcholine and phosphatidylethanolamine. | 2011 | Biochim. Biophys. Acta | pmid:21835265 |
| Niklas J et al. | High-throughput phospholipid quantitation in mammalian cells using matrix-assisted laser desorption ionization-time of flight mass spectrometry with N-trifluoroacetyl-phosphatidylethanolamine as internal standard. | 2011 | Anal. Biochem. | pmid:21910962 |
| Quinn PJ | The structure of complexes between phosphatidylethanolamine and glucosylceramide: a matrix for membrane rafts. | 2011 | Biochim. Biophys. Acta | pmid:21924237 |
| Garrett TA et al. | Non-enzymatically derived minor lipids found in Escherichia coli lipid extracts. | 2011 | Biochim. Biophys. Acta | pmid:21925285 |
| Hall BM et al. | Distinct functions of evolutionary conserved MSF1 and late embryogenesis abundant (LEA)-like domains in mitochondria. | 2011 | J. Biol. Chem. | pmid:21930701 |
| Fei W et al. | A role for phosphatidic acid in the formation of "supersized" lipid droplets. | 2011 | PLoS Genet. | pmid:21829381 |
| Raghava S et al. | The SV40 late protein VP4 is a viroporin that forms pores to disrupt membranes for viral release. | 2011 | PLoS Pathog. | pmid:21738474 |
| Leskova GF and Kryzhanovsky GN | Changes in phospholipid composition of cardiomyocyte plasma membranes during hemorrhagic shock. | 2011 | Bull. Exp. Biol. Med. | pmid:22451867 |
| Dashti M et al. | A phospholipidomic analysis of all defined human plasma lipoproteins. | 2011 | Sci Rep | pmid:22355656 |
| Zhang Y et al. | Crystal structure of the receptor binding domain of the botulinum C-D mosaic neurotoxin reveals potential roles of lysines 1118 and 1136 in membrane interactions. | 2011 | Biochem. Biophys. Res. Commun. | pmid:21130733 |
| Sanmarco M | Is testing for antiphosphatidylethanolamine antibodies clinically useful? | 2011 | Curr Rheumatol Rep | pmid:21061099 |
| Lee J and Choe E | Effects of phospholipids on the antioxidant activity of α-tocopherol in the singlet oxygen oxidation of canola oil. | 2011 | N Biotechnol | pmid:21621019 |
| Canadi Jurešić G and Blagović B | The influence of fermentation conditions and recycling on the phospholipid and fatty acid composition of the brewer's yeast plasma membranes. | 2011 | Folia Microbiol. (Praha) | pmid:21625876 |
| Sawant RR and Torchilin VP | Design and synthesis of novel functional lipid-based bioconjugates for drug delivery and other applications. | 2011 | Methods Mol. Biol. | pmid:21674343 |
| Fu S et al. | Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. | 2011 | Nature | pmid:21532591 |
| Suh M et al. | Testes of obese rats are highly responsive to n-3 long-chain fatty acids. | 2011 | Br. J. Nutr. | pmid:21486514 |
| Stafford JH and Thorpe PE | Increased exposure of phosphatidylethanolamine on the surface of tumor vascular endothelium. | 2011 | Neoplasia | pmid:21472134 |
| Chen YG et al. | Bacillus zhanjiangensis sp. nov., isolated from an oyster in South China Sea. | 2011 | Antonie Van Leeuwenhoek | pmid:20865333 |
| Godin LM et al. | Spatiotemporal dynamics of actin remodeling and endomembrane trafficking in alveolar epithelial type I cell wound healing. | 2011 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21216977 |
| Itakura E and Mizushima N | p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. | 2011 | J. Cell Biol. | pmid:21220506 |
| Romano I et al. | Salinivibrio sharmensis sp. nov., a novel haloalkaliphilic bacterium from a saline lake in Ras Mohammed Park (Egypt). | 2011 | Extremophiles | pmid:21287211 |
| Cazzaniga E et al. | Abeta peptide toxicity is reduced after treatments decreasing phosphatidylethanolamine content in differentiated neuroblastoma cells. | 2011 | Neurochem. Res. | pmid:21287268 |
| Garidel P et al. | Non-ideal mixing and fluid-fluid immiscibility in phosphatidic acid-phosphatidylethanolamine mixed bilayers. | 2011 | Eur. Biophys. J. | pmid:21598044 |
| Whitfield T et al. | The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein. | 2011 | Mol. Membr. Biol. | pmid:21604991 |