| MeSH term | MeSH ID | Detail |
|---|---|---|
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mead FC and Williams AJ | Electrostatic mechanisms underlie neomycin block of the cardiac ryanodine receptor channel (RyR2). | 2004 | Biophys. J. | pmid:15361409 |
| Zhang N et al. | [The enhancing effect of tomato lectin modified liposomes of insulin on oral absorption in mice]. | 2004 | Yao Xue Xue Bao | pmid:15338884 |
| Meuillet EJ et al. | Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. | 2004 | Arch. Biochem. Biophys. | pmid:15313215 |
| Moe MK et al. | Vicinal hydroxylation of unsaturated fatty acids for structural characterization of intact neutral phospholipids by negative electrospray ionization tandem quadrupole mass spectrometry. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15317043 |
| Sugai R et al. | Overexpression of gnsA, a multicopy suppressor of the secG null mutation, increases acidic phospholipid contents by inhibiting phosphatidylethanolamine synthesis at low temperatures. | 2004 | J. Bacteriol. | pmid:15317805 |
| Wang X et al. | A novel human phosphatidylethanolamine-binding protein resists tumor necrosis factor alpha-induced apoptosis by inhibiting mitogen-activated protein kinase pathway activation and phosphatidylethanolamine externalization. | 2004 | J. Biol. Chem. | pmid:15302887 |
| Doerrler WT et al. | MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli. | 2004 | J. Biol. Chem. | pmid:15304478 |
| Barker AP et al. | A novel extracellular phospholipase C of Pseudomonas aeruginosa is required for phospholipid chemotaxis. | 2004 | Mol. Microbiol. | pmid:15306013 |
| Khopade AJ et al. | Phase structures of a hydrated anionic phospholipid composition containing cationic dendrimers and pegylated lipids. | 2004 | Langmuir | pmid:15323476 |
| Odabaei G et al. | Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis. | 2004 | Adv. Cancer Res. | pmid:15327891 |
| Iwamoto K et al. | [Relationship between localized phosphatidylethanolamine exposure and yeast cell polarity]. | 2004 | Tanpakushitsu Kakusan Koso | pmid:15346886 |
| Riché EL et al. | Novel long-circulating liposomes containing peptide library-lipid conjugates: synthesis and in vivo behavior. | 2004 | J Drug Target | pmid:15545085 |
| Otto GP et al. | Dictyostelium macroautophagy mutants vary in the severity of their developmental defects. | 2004 | J. Biol. Chem. | pmid:14736886 |
| Choi HS et al. | Regulation of phospholipid synthesis in the yeast cki1Delta eki1Delta mutant defective in the Kennedy pathway. The Cho1-encoded phosphatidylserine synthase is regulated by mRNA stability. | 2004 | J. Biol. Chem. | pmid:14739287 |
| Ho SY et al. | Lipid metabolism in zebrafish. | 2004 | Methods Cell Biol. | pmid:15602873 |
| Wang C et al. | Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. | 2004 | Se Pu | pmid:15709398 |
| Edwards IJ et al. | Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. | 2004 | Clin. Cancer Res. | pmid:15623603 |
| Trajkovic-Bodennec S et al. | Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes. | 2004 Jul-Aug | Blood Cells Mol. Dis. | pmid:15223015 |
| Vasil'eva OB et al. | [Biochemical properties of the the lipoproteins lipid composition in fishes of the different ecology: trout Salmo irideus L. and whitefish Coregonus lavaretus L]. | 2004 Mar-Apr | Izv. Akad. Nauk. Ser. Biol. | pmid:15131975 |
| Malisiova F et al. | Liposomal formulations from phospholipids of Greek almond oil. Properties and biological activity. | 2004 May-Jun | Z. Naturforsch., C, J. Biosci. | pmid:18998396 |