| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nguyen TT et al. | Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance. | 2012 | Traffic | pmid:22409400 |
| Baronas ET et al. | Biomarkers to monitor drug-induced phospholipidosis. | 2007 | Toxicol. Appl. Pharmacol. | pmid:17156806 |
| Bertolaccini ML et al. | The clinical value of testing for antibodies to phosphatidylethanolamine (aPE) in patients with systemic lupus erythematosus (SLE). | 2012 | Thromb. Res. | pmid:23079292 |
| Sanmarco M et al. | Antiphosphatidylethanolamine antibodies are associated with an increased odds ratio for thrombosis. A multicenter study with the participation of the European Forum on antiphospholipid antibodies. | 2007 | Thromb. Haemost. | pmid:17549297 |
| Tavoosi N and Morrissey JH | Influence of membrane composition on the enhancement of factor VIIa/tissue factor activity by magnesium ions. | 2014 | Thromb. Haemost. | pmid:24285084 |
| Dennis MW et al. | Prothrombinase enhancement through quantitative and qualitative changes affecting very low density lipoprotein in complex with C-reactive protein. | 2004 | Thromb. Haemost. | pmid:14983228 |
| Wahlmüller FC et al. | New lipid interaction partners stimulate the inhibition of activated protein C by cell-penetrating protein C inhibitor. | 2014 | Thromb. Haemost. | pmid:24136361 |
| Nishida I | [Reverse genetic approaches for the significance of phospholipid metabolism at low temperatures]. | 2007 | Tanpakushitsu Kakusan Koso | pmid:17566349 |
| Iwamoto K et al. | [Relationship between localized phosphatidylethanolamine exposure and yeast cell polarity]. | 2004 | Tanpakushitsu Kakusan Koso | pmid:15346886 |
| Mizushima N | [Methods for monitoring macroautophagy]. | 2006 | Tanpakushitsu Kakusan Koso | pmid:16922435 |
| Krafft C et al. | Near infrared Raman spectra of human brain lipids. | 2005 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:15820887 |
| Emoto K | [Molecular basis for membrane lipid dynamics and its roles in cytoskeletal organization]. | 2008 | Seikagaku | pmid:18975616 |
| Aoyama C | [Function of choline kinase]. | 2010 | Seikagaku | pmid:20496749 |
| Zhao S et al. | [Metabonomics and phospholipid metabolic profiling of abnormal glucose metabolism based on high performance liquid chromatography-electrospray mass spectrometry]. | 2011 | Se Pu | pmid:21770239 |
| Wang C et al. | Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. | 2004 | Se Pu | pmid:15709398 |
| Zhou M et al. | Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding. | 2011 | Science | pmid:22021858 |
| Tsuboyama K et al. | The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. | 2016 | Science | pmid:27885029 |
| Begum H et al. | Discovering and validating between-subject variations in plasma lipids in healthy subjects. | 2016 | Sci Rep | pmid:26743939 |
| Dashti M et al. | A phospholipidomic analysis of all defined human plasma lipoproteins. | 2011 | Sci Rep | pmid:22355656 |
| Kojima R et al. | A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro. | 2016 | Sci Rep | pmid:27469264 |