| MeSH term | MeSH ID | Detail |
|---|---|---|
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Hyperhomocysteinemia | D020138 | 6 associated lipids |
| Trematode Infections | D014201 | 8 associated lipids |
| Tangier Disease | D013631 | 8 associated lipids |
| Bacteremia | D016470 | 9 associated lipids |
| Toxoplasmosis | D014123 | 9 associated lipids |
| Thinness | D013851 | 11 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Myocardial Ischemia | D017202 | 11 associated lipids |
| Iron Overload | D019190 | 11 associated lipids |
| Venous Thrombosis | D020246 | 11 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Merino-Montero S et al. | Effects of lactose permease of Escherichia coli on the anisotropy and electrostatic surface potential of liposomes. | 2006 | Biophys. Chem. | pmid:16242835 |
| Kaliszewski P et al. | Enhanced levels of Pis1p (phosphatidylinositol synthase) improve the growth of Saccharomyces cerevisiae cells deficient in Rsp5 ubiquitin ligase. | 2006 | Biochem. J. | pmid:16363994 |
| Wichmann O et al. | A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16323228 |
| Bourre JM et al. | Fatty acid alterations in liver peroxisomes from n-3-deficient mice. | 2006 | Ann. Nutr. Metab. | pmid:16407648 |
| Song H et al. | Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16105858 |
| Bonner PJ and Shimkets LJ | Phospholipid directed motility of surface-motile bacteria. | 2006 | Mol. Microbiol. | pmid:16925549 |
| Matsumoto K et al. | Lipid domains in bacterial membranes. | 2006 | Mol. Microbiol. | pmid:16925550 |
| Bonner PJ et al. | FibA and PilA act cooperatively during fruiting body formation of Myxococcus xanthus. | 2006 | Mol. Microbiol. | pmid:16925559 |
| Sokol DK et al. | Obsessive-compulsive disorder and central nervous system autoimmunity. | 2006 | Br J Psychiatry | pmid:16880498 |
| Moon TC et al. | Ochnaflavone, naturally occurring biflavonoid, inhibits phospholipase A2 dependent phosphatidylethanolamine degradation in a CCl4-induced rat liver microsome. | 2006 | Biol. Pharm. Bull. | pmid:17142963 |
| Yoon SJ et al. | Interaction of N-linked glycans, having multivalent GlcNAc termini, with GM3 ganglioside. | 2006 | Glycoconj. J. | pmid:17115280 |
| Pernet F et al. | Comparison of three solid-phase extraction methods for fatty acid analysis of lipid fractions in tissues of marine bivalves. | 2006 | J Chromatogr A | pmid:17097094 |
| Tanaka A et al. | Peroxisome division is impaired in a CHO cell mutant with an inactivating point-mutation in dynamin-like protein 1 gene. | 2006 | Exp. Cell Res. | pmid:16529741 |
| Dabholkar RD et al. | Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. | 2006 | Int J Pharm | pmid:16616818 |
| Kume H and Sasaki H | Ethanolamine modulates DNA synthesis through epidermal growth factor receptor in rat primary hepatocytes. | 2006 Jan-Feb | In Vitro Cell. Dev. Biol. Anim. | pmid:16618207 |
| Sawant RM et al. | "SMART" drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers. | 2006 Jul-Aug | Bioconjug. Chem. | pmid:16848401 |
| Dubielecka PM et al. | Mitoxantrone changes spectrin-aminophospholipid interactions. | 2006 May-Jun | Mol. Membr. Biol. | pmid:16785207 |
| Tang N et al. | Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin. | 2007 | J. Natl. Cancer Inst. | pmid:17596572 |
| Epand RF et al. | Bacterial lipid composition and the antimicrobial efficacy of cationic steroid compounds (Ceragenins). | 2007 | Biochim. Biophys. Acta | pmid:17599802 |
| Li D et al. | Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells. | 2007 | J. Pharmacol. Sci. | pmid:17895587 |