| MeSH term | MeSH ID | Detail |
|---|---|---|
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Hyperhomocysteinemia | D020138 | 6 associated lipids |
| Trematode Infections | D014201 | 8 associated lipids |
| Tangier Disease | D013631 | 8 associated lipids |
| Bacteremia | D016470 | 9 associated lipids |
| Toxoplasmosis | D014123 | 9 associated lipids |
| Thinness | D013851 | 11 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Myocardial Ischemia | D017202 | 11 associated lipids |
| Iron Overload | D019190 | 11 associated lipids |
| Venous Thrombosis | D020246 | 11 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kol MA et al. | Uptake and remodeling of exogenous phosphatidylethanolamine in E. coli. | 2004 | Biochim. Biophys. Acta | pmid:15164768 |
| Brown AJ | Of cholesterol-free mice and men. | 2004 | Curr. Opin. Lipidol. | pmid:15166797 |
| Mead FC and Williams AJ | Electrostatic mechanisms underlie neomycin block of the cardiac ryanodine receptor channel (RyR2). | 2004 | Biophys. J. | pmid:15361409 |
| Zhang N et al. | [The enhancing effect of tomato lectin modified liposomes of insulin on oral absorption in mice]. | 2004 | Yao Xue Xue Bao | pmid:15338884 |
| Meuillet EJ et al. | Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. | 2004 | Arch. Biochem. Biophys. | pmid:15313215 |
| Moe MK et al. | Vicinal hydroxylation of unsaturated fatty acids for structural characterization of intact neutral phospholipids by negative electrospray ionization tandem quadrupole mass spectrometry. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15317043 |
| Sugai R et al. | Overexpression of gnsA, a multicopy suppressor of the secG null mutation, increases acidic phospholipid contents by inhibiting phosphatidylethanolamine synthesis at low temperatures. | 2004 | J. Bacteriol. | pmid:15317805 |
| Wang Y et al. | Regulation of signal peptidase by phospholipids in membrane: characterization of phospholipid bilayer incorporated Escherichia coli signal peptidase. | 2004 | Biochemistry | pmid:14705954 |
| Bleijerveld OB et al. | Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol. | 2004 | Biochem. J. | pmid:14759225 |
| Otto GP et al. | Dictyostelium macroautophagy mutants vary in the severity of their developmental defects. | 2004 | J. Biol. Chem. | pmid:14736886 |
| Choi HS et al. | Regulation of phospholipid synthesis in the yeast cki1Delta eki1Delta mutant defective in the Kennedy pathway. The Cho1-encoded phosphatidylserine synthase is regulated by mRNA stability. | 2004 | J. Biol. Chem. | pmid:14739287 |
| Kobayashi S et al. | Membrane translocation mechanism of the antimicrobial peptide buforin 2. | 2004 | Biochemistry | pmid:15581374 |
| Ho SY et al. | Lipid metabolism in zebrafish. | 2004 | Methods Cell Biol. | pmid:15602873 |
| Schaur RJ | Basic aspects of the biochemical reactivity of 4-hydroxynonenal. | 2003 Aug-Oct | Mol. Aspects Med. | pmid:12892992 |
| Sehayek E et al. | Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol. | 2003 | J. Lipid Res. | pmid:12810817 |
| Prades J et al. | Effects of unsaturated fatty acids and triacylglycerols on phosphatidylethanolamine membrane structure. | 2003 | J. Lipid Res. | pmid:12810821 |
| Noga AA and Vance DE | Insights into the requirement of phosphatidylcholine synthesis for liver function in mice. | 2003 | J. Lipid Res. | pmid:12837848 |
| Casals E et al. | Physical stability of liposomes bearing hemostatic activity. | 2003 | Chem. Phys. Lipids | pmid:14499472 |
| Alvis SJ et al. | Interactions of anionic phospholipids and phosphatidylethanolamine with the potassium channel KcsA. | 2003 | Biophys. J. | pmid:14645072 |
| Avrahami D and Shai Y | Bestowing antifungal and antibacterial activities by lipophilic acid conjugation to D,L-amino acid-containing antimicrobial peptides: a plausible mode of action. | 2003 | Biochemistry | pmid:14674771 |