| MeSH term | MeSH ID | Detail |
|---|---|---|
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Hyperhomocysteinemia | D020138 | 6 associated lipids |
| Trematode Infections | D014201 | 8 associated lipids |
| Tangier Disease | D013631 | 8 associated lipids |
| Bacteremia | D016470 | 9 associated lipids |
| Toxoplasmosis | D014123 | 9 associated lipids |
| Thinness | D013851 | 11 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Myocardial Ischemia | D017202 | 11 associated lipids |
| Iron Overload | D019190 | 11 associated lipids |
| Venous Thrombosis | D020246 | 11 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Garrett TA et al. | Non-enzymatically derived minor lipids found in Escherichia coli lipid extracts. | 2011 | Biochim. Biophys. Acta | pmid:21925285 |
| Largo E et al. | Ion channel activity of the CSFV p7 viroporin in surrogates of the ER lipid bilayer. | 2016 | Biochim. Biophys. Acta | pmid:26464198 |
| Ariöz C et al. | Heterologous overexpression of a monotopic glucosyltransferase (MGS) induces fatty acid remodeling in Escherichia coli membranes. | 2014 | Biochim. Biophys. Acta | pmid:24726609 |
| Kol MA et al. | Uptake and remodeling of exogenous phosphatidylethanolamine in E. coli. | 2004 | Biochim. Biophys. Acta | pmid:15164768 |
| Sarabipour S et al. | Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation. | 2015 | Biochim. Biophys. Acta | pmid:25896659 |
| Miyamoto S and Tokuda H | Diverse effects of phospholipids on lipoprotein sorting and ATP hydrolysis by the ABC transporter LolCDE complex. | 2007 | Biochim. Biophys. Acta | pmid:17498646 |
| Strömstedt AA et al. | Bactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra. | 2017 | Biochim. Biophys. Acta | pmid:28669767 |
| Ikon N and Ryan RO | Cardiolipin and mitochondrial cristae organization. | 2017 | Biochim. Biophys. Acta | pmid:28336315 |
| Deng X et al. | iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling. | 2016 | Biochim. Biophys. Acta | pmid:26873633 |
| Kannan M et al. | Endoplasmic reticulum stress affects the transport of phosphatidylethanolamine from mitochondria to the endoplasmic reticulum in S.cerevisiae. | 2016 | Biochim. Biophys. Acta | pmid:27678054 |
| Tatsuta T and Langer T | Intramitochondrial phospholipid trafficking. | 2017 | Biochim. Biophys. Acta | pmid:27542541 |
| Opekarová M et al. | Differential effect of phosphatidylethanolamine depletion on raft proteins: further evidence for diversity of rafts in Saccharomyces cerevisiae. | 2005 | Biochim. Biophys. Acta | pmid:15904666 |
| Reichel M et al. | Alterations of plasma glycerophospholipid and sphingolipid species in male alcohol-dependent patients. | 2015 | Biochim. Biophys. Acta | pmid:26291032 |
| Marsh D | Structural and thermodynamic determinants of chain-melting transition temperatures for phospholipid and glycolipids membranes. | 2010 | Biochim. Biophys. Acta | pmid:19853577 |
| Stark B et al. | Association of vasoactive intestinal peptide with polymer-grafted liposomes: structural aspects for pulmonary delivery. | 2007 | Biochim. Biophys. Acta | pmid:17204237 |
| Deng L et al. | Incorporation and remodeling of phosphatidylethanolamine containing short acyl residues in yeast. | 2010 | Biochim. Biophys. Acta | pmid:20176132 |
| Martin ML et al. | The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid. | 2013 | Biochim. Biophys. Acta | pmid:23360770 |
| Bogdanov M et al. | Lipids and topological rules governing membrane protein assembly. | 2014 | Biochim. Biophys. Acta | pmid:24341994 |
| Strömstedt AA et al. | Selective membrane disruption by the cyclotide kalata B7: complex ions and essential functional groups in the phosphatidylethanolamine binding pocket. | 2016 | Biochim. Biophys. Acta | pmid:26878982 |
| Pasenkiewicz-Gierula M et al. | Computer modelling studies of the bilayer/water interface. | 2016 | Biochim. Biophys. Acta | pmid:26825705 |