PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Beer KB et al. | Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry. | 2018 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29367422 |
Liu Q et al. | Flavobacterium hankyongi sp. nov., isolated from activated sludge. | 2018 | Int. J. Syst. Evol. Microbiol. | pmid:29620495 |
Franco A et al. | Winogradskyella pocilloporae sp. nov. isolated from healthy tissue of the coral Pocillopora damicornis. | 2018 | Int. J. Syst. Evol. Microbiol. | pmid:29620493 |
Wang NN et al. | Aquimarina celericrescens sp. nov., isolated from seawater. | 2018 | Int. J. Syst. Evol. Microbiol. | pmid:29580323 |
Park S et al. | Jannaschia confluentis sp. nov., isolated from the junction between the ocean and a freshwater spring. | 2018 | Int. J. Syst. Evol. Microbiol. | pmid:29388543 |
Kaur M et al. | Sphingobacterium bovisgrunnientis sp. nov., isolated from yak milk. | 2018 | Int. J. Syst. Evol. Microbiol. | pmid:29388539 |
Vazquez-de-Lara LG et al. | Phosphatidylethanolamine Induces an Antifibrotic Phenotype in Normal Human Lung Fibroblasts and Ameliorates Bleomycin-Induced Lung Fibrosis in Mice. | 2018 | Int J Mol Sci | pmid:30223424 |
Miyata N et al. | Porin proteins have critical functions in mitochondrial phospholipid metabolism in yeast. | 2018 | J. Biol. Chem. | pmid:30237174 |
Liu SQ et al. | Muricauda iocasae sp. nov., isolated from deep sea sediment of the South China Sea. | 2018 | Int. J. Syst. Evol. Microbiol. | pmid:29932387 |
Wei Y et al. | Pseudomonas abyssi sp. nov., isolated from the abyssopelagic water of the Mariana Trench. | 2018 | Int. J. Syst. Evol. Microbiol. | pmid:29927369 |