PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Rojas-Betancourt S et al. | Gas-Phase Chemical Separation of Phosphatidylcholine and Phosphatidylethanolamine Cations via Charge Inversion Ion/Ion Chemistry. | 2015 | Anal. Chem. | pmid:26477819 |
Pham HT and Julian RR | Mass shifting and radical delivery with crown ether attachment for separation and analysis of phosphatidylethanolamine lipids. | 2014 | Anal. Chem. | pmid:24548103 |
Wang X et al. | Profiling and relative quantification of phosphatidylethanolamine based on acetone stable isotope derivatization. | 2016 | Anal. Chim. Acta | pmid:26703264 |
Chen S et al. | Structural elucidation of molecular species of pacific oyster ether amino phospholipids by normal-phase liquid chromatography/negative-ion electrospray ionization and quadrupole/multiple-stage linear ion-trap mass spectrometry. | 2012 | Anal. Chim. Acta | pmid:22713920 |
STEINBERG BL | Intravenous procaine; its effect on liver function in man as determined by the cephalin flocculation test. | 1949 | Anesthesiology | pmid:15393676 |
Wichmann O et al. | A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16323228 |
Sanmarco M et al. | Antigenic profile, prevalence, and clinical significance of antiphospholipid antibodies in women referred for in vitro fertilization. | 2007 | Ann. N. Y. Acad. Sci. | pmid:17894010 |
FRIEDMAN HH et al. | ODOR MEASUREMENT POSSIBILITIES VIA ENERGY CHANGES IN CEPHALIN MONOLAYERS. | 1964 | Ann. N. Y. Acad. Sci. | pmid:14220554 |
Decsi T et al. | Inverse association between trans isomeric and long-chain polyunsaturated fatty acids in pregnant women and their newborns: data from three European countries. | 2011 | Ann. Nutr. Metab. | pmid:22142767 |
Lohner S et al. | Gender differences in the long-chain polyunsaturated fatty acid status: systematic review of 51 publications. | 2013 | Ann. Nutr. Metab. | pmid:23327902 |
Bourre JM et al. | Fatty acid alterations in liver peroxisomes from n-3-deficient mice. | 2006 | Ann. Nutr. Metab. | pmid:16407648 |
Pan XQ and Lee RJ | In vivo antitumor activity of folate receptor-targeted liposomal daunorubicin in a murine leukemia model. | 2005 Jan-Feb | Anticancer Res. | pmid:15816557 |
Kerrinnes T et al. | Phospholipase A1 modulates the cell envelope phospholipid content of Brucella melitensis, contributing to polymyxin resistance and pathogenicity. | 2015 | Antimicrob. Agents Chemother. | pmid:26282427 |
Adibhatla RM et al. | Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia. | 2003 | Antioxid. Redox Signal. | pmid:14580322 |
Kim DH et al. | Flavobacterium panacis sp. nov., isolated from rhizosphere of Panax ginseng. | 2016 | Antonie Van Leeuwenhoek | pmid:27357576 |
Park S et al. | Algibacter miyuki sp. nov., a member of the family Flavobacteriaceae isolated from leachate of a brown algae reservoir. | 2013 | Antonie Van Leeuwenhoek | pmid:23733003 |
Chhetri G et al. | Edaphorhabdus rosea gen. nov., sp. nov., a new member of the family Cytophagaceae isolated from soil in South Korea. | 2018 | Antonie Van Leeuwenhoek | pmid:30027519 |
Kim SY et al. | Flavobacterium knui sp. nov., a novel member of the family Flavobacteriaceae. | 2018 | Antonie Van Leeuwenhoek | pmid:30022265 |
Chen Q et al. | Flavobacterium zaozhuangense sp. nov., a new member of the family Flavobacteriaceae, isolated from metolachlor-contaminated soil. | 2018 | Antonie Van Leeuwenhoek | pmid:29713912 |
Lee H et al. | Flavisolibacter carri sp. nov., isolated from an automotive air-conditioning system. | 2018 | Antonie Van Leeuwenhoek | pmid:29671178 |