PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Park S et al. | Algibacter miyuki sp. nov., a member of the family Flavobacteriaceae isolated from leachate of a brown algae reservoir. | 2013 | Antonie Van Leeuwenhoek | pmid:23733003 |
Chhetri G et al. | Edaphorhabdus rosea gen. nov., sp. nov., a new member of the family Cytophagaceae isolated from soil in South Korea. | 2018 | Antonie Van Leeuwenhoek | pmid:30027519 |
Chen Q et al. | Flavobacterium zaozhuangense sp. nov., a new member of the family Flavobacteriaceae, isolated from metolachlor-contaminated soil. | 2018 | Antonie Van Leeuwenhoek | pmid:29713912 |
Elvas F et al. | Phosphatidylethanolamine targeting for cell death imaging in early treatment response evaluation and disease diagnosis. | 2017 | Apoptosis | pmid:28623512 |
Lau BY et al. | Fat-1 gene modulates the fatty acid composition of femoral and vertebral phospholipids. | 2010 | Appl Physiol Nutr Metab | pmid:20725110 |
Johnson TJ et al. | The infrared spectra of Bacillus bacteria part I: vegetative Bacillus versus sporulated cells and the contributions of phospholipids to vegetative infrared spectra. | 2009 | Appl Spectrosc | pmid:19678986 |
Kim YA et al. | Integration of Quercetin-Iron Complexes into Phosphatidylcholine or Phosphatidylethanolamine Liposomes. | 2015 | Appl. Biochem. Biotechnol. | pmid:26047928 |
Henderson CM et al. | Fermentation temperature modulates phosphatidylethanolamine and phosphatidylinositol levels in the cell membrane of Saccharomyces cerevisiae. | 2013 | Appl. Environ. Microbiol. | pmid:23811519 |
Moore EK et al. | Novel mono-, di-, and trimethylornithine membrane lipids in northern wetland planctomycetes. | 2013 | Appl. Environ. Microbiol. | pmid:23995937 |
Cerminati S et al. | Development of a highly efficient oil degumming process using a novel phosphatidylinositol-specific phospholipase C enzyme. | 2017 | Appl. Microbiol. Biotechnol. | pmid:28238084 |
Lageix F et al. | [Association between the presence of antiphospholipid antibodies and the occurrence of autism spectrum disorder in childhood]. | 2015 | Arch Pediatr | pmid:26386813 |
Meuillet EJ et al. | Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. | 2004 | Arch. Biochem. Biophys. | pmid:15313215 |
REHBINDER D and GREENBERG DM | STUDIES ON THE METHYLATION OF ETHANOLAMINE PHOSPHATIDES BY LIVER PREPARATIONS. | 1965 | Arch. Biochem. Biophys. | pmid:14281933 |
CRUZ WO et al. | Crude cephalin as the active substance of organ extracts able to convert venous blood into hemostatic blood. | 1959 | Arch. Biochem. Biophys. | pmid:13813116 |
MCCANDLESS EL and ZILVERSMIT DB | The effect of cholesterol on the turnover of lecithin, cephalin and sphingomyelin in the rabbit. | 1956 | Arch. Biochem. Biophys. | pmid:13328128 |
Ansari IH et al. | Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion. | 2017 | Arch. Biochem. Biophys. | pmid:28193492 |
Gai Z et al. | Characterization of Atg8 in lepidopteran insect cells. | 2013 | Arch. Insect Biochem. Physiol. | pmid:23959953 |
Ma K et al. | Bacillus vini sp. nov. isolated from alcohol fermentation pit mud. | 2016 | Arch. Microbiol. | pmid:27055557 |
Sultanpuram VR et al. | Bacillus alcaliphilum sp. nov., a bacterium isolated from a soda lake. | 2017 | Arch. Microbiol. | pmid:28653084 |
Yoon J et al. | Spongiibacterium fuscum sp. nov., a marine Flavobacteriaceae isolated from the hard coral Galaxea fascicularis. | 2018 | Arch. Microbiol. | pmid:29955925 |