PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Abortion, Habitual D000026 5 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alzheimer Disease D000544 76 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Cataract D002386 34 associated lipids
Cholestasis, Intrahepatic D002780 4 associated lipids
Choline Deficiency D002796 16 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Epilepsy D004827 35 associated lipids
Fatty Liver D005234 48 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Galactosemias D005693 5 associated lipids
Hamartoma Syndrome, Multiple D006223 1 associated lipids
Hemolysis D006461 131 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Boumann HA et al. The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro. 2004 J. Biol. Chem. pmid:15258140
Laurinavicius S et al. The origin of phospholipids of the enveloped bacteriophage phi6. 2004 Virology pmid:15262506
Sugi T et al. Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss. 2004 J. Obstet. Gynaecol. Res. pmid:15238112
Demana PH et al. Incorporation of ovalbumin into ISCOMs and related colloidal particles prepared by the lipid film hydration method. 2004 Int J Pharm pmid:15196631
Liu F et al. Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers. 2004 Biophys. J. pmid:15454444
Papo N and Shai Y Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides. 2004 Biochemistry pmid:15157073
Demana PH et al. A comparison of pseudo-ternary diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by lipid-film hydration and dialysis. 2004 J. Pharm. Pharmacol. pmid:15142333
Zhang WN et al. Separation of phosphatidylcholine and phosphatidylethanolamine by using high-performance displacement chromatography. 2004 J Chromatogr A pmid:15146915
Riché EL et al. Novel long-circulating liposomes containing peptide library-lipid conjugates: synthesis and in vivo behavior. 2004 J Drug Target pmid:15545085
Berson EL et al. Further evaluation of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment: subgroup analyses. 2004 Arch. Ophthalmol. pmid:15364709
Bernoud-Hubac N et al. Covalent binding of isoketals to ethanolamine phospholipids. 2004 Free Radic. Biol. Med. pmid:15477011
Li SY et al. [Cell membrane phospholipid variation and protein kinase C expression effects on hepatic metastasis of large intestinal carcinoma]. 2004 Zhonghua Wai Ke Za Zhi pmid:15009987
Montes LR et al. Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes. 2004 Biochemistry pmid:15035639
Shaikh SR et al. Oleic and docosahexaenoic acid differentially phase separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study. 2004 Biophys. J. pmid:15345554
Dennis MW et al. Prothrombinase enhancement through quantitative and qualitative changes affecting very low density lipoprotein in complex with C-reactive protein. 2004 Thromb. Haemost. pmid:14983228
Darville T et al. Protection against Chlamydia trachomatis infection in vitro and modulation of inflammatory response in vivo by membrane-bound glycosaminoglycans. 2004 Microbes Infect. pmid:15050964
Schleheck D et al. Parvibaculum lavamentivorans gen. nov., sp. nov., a novel heterotroph that initiates catabolism of linear alkylbenzenesulfonate. 2004 Int. J. Syst. Evol. Microbiol. pmid:15388700
Wang C et al. Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. 2004 Se Pu pmid:15709398
Edwards IJ et al. Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. 2004 Clin. Cancer Res. pmid:15623603
Elmes M et al. The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. 2004 Biochim. Biophys. Acta pmid:15522830