PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Gu Z et al. | Hymenobacter frigidus sp. nov., isolated from a glacier ice core. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:28901897 |
Kim JM et al. | Parapedobacter lycopersici sp. nov., isolated from the rhizosphere soil of tomato plants (Solanum lycopersicum L.). | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:28895519 |
Li W et al. | Spirosoma lituiforme sp. nov., isolated from soil. | 2017 | J. Microbiol. | pmid:29076068 |
Zhou MY et al. | Flavobacterium ardleyense sp. nov., isolated from Antarctic soil. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:28893368 |
Meltzer S et al. | Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons. | 2017 | Cell Rep | pmid:29069593 |
Ahn JH et al. | Flavobacterium fluminis sp. nov. to accommodate an aerobic, halotolerant and gliding flavobacterium isolated from freshwater. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:28771125 |
Di Bartolomeo F et al. | Involvement of a putative substrate binding site in the biogenesis and assembly of phosphatidylserine decarboxylase 1 from Saccharomyces cerevisiae. | 2017 | Biochim. Biophys. Acta | pmid:28473294 |
Aldrovandi M et al. | DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression. | 2017 | Redox Biol | pmid:28160743 |
Dahal RH et al. | Rurimicrobium arvi gen. nov., sp. nov., a member of the family Chitinophagaceae isolated from farmland soil. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:29072559 |
Patel D and Witt SN | Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease. | 2017 | Oxid Med Cell Longev | pmid:28785375 |
Fan J et al. | A Central Role for Triacylglycerol in Membrane Lipid Breakdown, Fatty Acid -Oxidation, and Plant Survival under Extended Darkness. | 2017 | Plant Physiol. | pmid:28572457 |
Mitroi DN et al. | SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production. | 2017 | Autophagy | pmid:28521611 |
Saxena R et al. | Preclinical Development of a Nontoxic Oral Formulation of Monoethanolamine, a Lipid Precursor, for Prostate Cancer Treatment. | 2017 | Clin. Cancer Res. | pmid:28167510 |
Li DD et al. | Arcticibacterium luteifluviistationis gen. nov., sp. nov., isolated from Arctic seawater. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:27902275 |
Lee JJ et al. | Hymenobacter seoulensis sp. nov., isolated from river water. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:27902264 |
Liu H et al. | Flavobacterium luticocti sp. nov., isolated from wastewater. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:27902260 |
Neumann J et al. | Diverse relations between ABC transporters and lipids: An overview. | 2017 | Biochim. Biophys. Acta | pmid:27693344 |
Ansari IH et al. | Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion. | 2017 | Arch. Biochem. Biophys. | pmid:28193492 |
Sabharwal T et al. | Defense related decadienal elicits membrane lipid remodeling in the diatom Phaeodactylum tricornutum. | 2017 | PLoS ONE | pmid:28582415 |
Wang N et al. | Changchengzhania lutea gen. nov., sp. nov., a new member of the family Flavobacteriaceae isolated from Antarctic intertidal sediment. | 2017 | Int. J. Syst. Evol. Microbiol. | pmid:29068279 |