PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Abortion, Habitual D000026 5 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alzheimer Disease D000544 76 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Cataract D002386 34 associated lipids
Cholestasis, Intrahepatic D002780 4 associated lipids
Choline Deficiency D002796 16 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Epilepsy D004827 35 associated lipids
Fatty Liver D005234 48 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Galactosemias D005693 5 associated lipids
Hamartoma Syndrome, Multiple D006223 1 associated lipids
Hemolysis D006461 131 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Nishibori A et al. Phosphatidylethanolamine domains and localization of phospholipid synthases in Bacillus subtilis membranes. 2005 J. Bacteriol. pmid:15743965
Krafft C et al. Near infrared Raman spectra of human brain lipids. 2005 Spectrochim Acta A Mol Biomol Spectrosc pmid:15820887
Maeda A et al. Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. 2005 J. Biol. Chem. pmid:15755727
Morita YS et al. Compartmentalization of lipid biosynthesis in mycobacteria. 2005 J. Biol. Chem. pmid:15805104
Goss R et al. Role of hexagonal structure-forming lipids in diadinoxanthin and violaxanthin solubilization and de-epoxidation. 2005 Biochemistry pmid:15751979
Zhai X et al. Small angle X-ray scattering (SAXS) and differential scanning calorimetry (DSC) studies of amide phospholipids. 2005 Chem. Phys. Lipids pmid:15589228
Nguyen LT et al. Structural studies and model membrane interactions of two peptides derived from bovine lactoferricin. 2005 J. Pept. Sci. pmid:15635665
Kamimori H et al. Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. 2005 Anal. Biochem. pmid:15649388
Murzyn K et al. Phosphatidylethanolamine-phosphatidylglycerol bilayer as a model of the inner bacterial membrane. 2005 Biophys. J. pmid:15556990
Pacetti D et al. High performance liquid chromatography-tandem mass spectrometry of phospholipid molecular species in eggs from hens fed diets enriched in seal blubber oil. 2005 J Chromatogr A pmid:16298186
Müller H et al. A diet rich in phosphatidylethanolamine increases plasma homocysteine in mink: a comparison with a soybean oil diet. 2005 Br. J. Nutr. pmid:16277769
Tsukamoto K et al. Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. 2005 J. Biol. Chem. pmid:16115873
Suits F et al. Molecular dynamics investigation of the structural properties of phosphatidylethanolamine lipid bilayers. 2005 J Chem Phys pmid:16035800
Pitman MC et al. Molecular dynamics investigation of dynamical properties of phosphatidylethanolamine lipid bilayers. 2005 J Chem Phys pmid:16035801
Gohil VM et al. Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae. 2005 J. Biol. Chem. pmid:16036913
Ahn T et al. Involvement of nonlamellar-prone lipids in the stability increase of human cytochrome P450 1A2 in reconstituted membranes. 2005 Biochemistry pmid:15966743
Novikova NN et al. X-ray fluorescence methods for investigations of lipid/protein membrane models. 2005 J Synchrotron Radiat pmid:15968131
Lee ES et al. The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells. 2005 Neurotoxicology pmid:15950286
Jacobs RL et al. Physiological regulation of phospholipid methylation alters plasma homocysteine in mice. 2005 J. Biol. Chem. pmid:15958390
Kalashnikova LA et al. [Anti-phosphatidylethanolamine antibodies in patients with Sneddon's syndrome]. 2005 Klin Med (Mosk) pmid:15984583