PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Willumeit R et al. | Structural rearrangement of model membranes by the peptide antibiotic NK-2. | 2005 | Biochim. Biophys. Acta | pmid:15893515 |
Bogdanov M et al. | Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesis. | 2005 | Methods | pmid:15894490 |
Koutoku T et al. | Central administration of phosphatidylserine attenuates isolation stress-induced behavior in chicks. | 2005 | Neurochem. Int. | pmid:15916832 |
López-Revuelta A et al. | Increase in vulnerability to oxidative damage in cholesterol-modified erythrocytes exposed to t-BuOOH. | 2005 | Biochim. Biophys. Acta | pmid:15866485 |
Fishkin NE et al. | Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15870200 |
Sennato S et al. | Evidence of domain formation in cardiolipin-glycerophospholipid mixed monolayers. A thermodynamic and AFM study. | 2005 | J Phys Chem B | pmid:16853024 |
Andrä J et al. | Investigation into the interaction of the phosphoporin PhoE with outer membrane lipids: physicochemical characterization and biological activity. | 2005 | Med Chem | pmid:16787338 |
Alves ID et al. | Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy. | 2005 | Biophys. J. | pmid:15501933 |
Jernigan Jr HM et al. | Effects of cataractogenesis on the CDP-choline pathway: increased phospholipid synthesis in lenses from galactosemic rats and 13/N guinea pigs. | 2005 Jan-Feb | Ophthalmic Res. | pmid:15604593 |
Pan XQ and Lee RJ | In vivo antitumor activity of folate receptor-targeted liposomal daunorubicin in a murine leukemia model. | 2005 Jan-Feb | Anticancer Res. | pmid:15816557 |
Funari SS et al. | Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes. | 2005 Jul-Aug | Mol. Membr. Biol. | pmid:16154902 |
Hocquellet A et al. | Evidence for a different metabolism of PC and PE in shoots and roots. | 2005 Oct-Nov | Plant Physiol. Biochem. | pmid:16325411 |
Kolomytseva MP et al. | [Heterogeneity of Rhodococcus opacus 1CP as a response to stress induced by chlorophenols]. | 2005 Sep-Oct | Prikl. Biokhim. Mikrobiol. | pmid:16240653 |
Clark MC et al. | NMR assignment of rat Raf kinase inhibitor protein. | 2006 | J. Biomol. NMR | pmid:16456706 |
Oberfeld B et al. | Phospholipids occupy the internal lumen of the c ring of the ATP synthase of Escherichia coli. | 2006 | Biochemistry | pmid:16460030 |
Wachtel E et al. | A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes. | 2006 | Biochemistry | pmid:16430232 |
Shizuka M et al. | Synthesis of isoprostanyl phosphatidylcholine and isoprostanyl phosphatidylethanolamine. | 2006 | J. Org. Chem. | pmid:16468779 |
Russano AM et al. | Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. | 2006 | J. Allergy Clin. Immunol. | pmid:16675349 |
Li Z et al. | The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. | 2006 | Cell Metab. | pmid:16679290 |
Sternin E et al. | Changes in molecular order across the lamellar-to-inverted hexagonal phase transition depend on the position of the double-bond in mono-unsaturated phospholipid dispersions. | 2006 | Chem. Phys. Lipids | pmid:16574088 |