| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Myocardial Ischemia | D017202 | 11 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Blois A et al. | Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. | 2006 | Regul. Pept. | pmid:16445995 |
| Dolegowska B et al. | Effect of hemodialysis on the content of fatty acids in monolayers of erythrocyte membranes in patients with chronic renal failure. | 2007 | Ren Fail | pmid:17497467 |
| Cesari AB et al. | Changes in the lipid composition of Bradyrhizobium cell envelope reveal a rapid response to water deficit involving lysophosphatidylethanolamine synthesis from phosphatidylethanolamine in outer membrane. | Res. Microbiol. | pmid:29864488 | |
| Nayfe R et al. | Seronegative antiphospholipid syndrome. | 2013 | Rheumatology (Oxford) | pmid:23502076 |
| Bălănescu P et al. | Association of anti phosphatidyl ethanolamine antibodies and low complement levels in systemic sclerosis patients--results of a cross-sectional study. | 2015 | Scand. J. Clin. Lab. Invest. | pmid:26067612 |
| Admasu TD et al. | Lipid profiling of C. elegans strains administered pro-longevity drugs and drug combinations. | 2018 | Sci Data | pmid:30351306 |
| Shahine A et al. | A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. | 2017 | Sci Immunol | pmid:29054999 |
| Begum H et al. | Discovering and validating between-subject variations in plasma lipids in healthy subjects. | 2016 | Sci Rep | pmid:26743939 |
| Farine L et al. | Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei. | 2015 | Sci Rep | pmid:26577437 |
| Montaner A et al. | Specific Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cells. | 2018 | Sci Rep | pmid:29323239 |
| Kim JS et al. | The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin. | 2017 | Sci Rep | pmid:28740220 |
| Dória ML et al. | Epithelial ovarian carcinoma diagnosis by desorption electrospray ionization mass spectrometry imaging. | 2016 | Sci Rep | pmid:27976698 |
| Serrán-Aguilera L et al. | Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death. | 2016 | Sci Rep | pmid:27616047 |
| Shin H et al. | Genome-wide transcriptome analysis revealed organelle specific responses to temperature variations in algae. | 2016 | Sci Rep | pmid:27883062 |
| Dashti M et al. | A phospholipidomic analysis of all defined human plasma lipoproteins. | 2011 | Sci Rep | pmid:22355656 |
| Kojima R et al. | A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro. | 2016 | Sci Rep | pmid:27469264 |
| Dimitrova M et al. | CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition. | 2016 | Sci Rep | pmid:27040328 |
| Zhou M et al. | Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding. | 2011 | Science | pmid:22021858 |
| Tsuboyama K et al. | The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. | 2016 | Science | pmid:27885029 |
| Wang C et al. | Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. | 2004 | Se Pu | pmid:15709398 |