PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Belov GA | Less Grease, Please. Phosphatidylethanolamine Is the Only Lipid Required for Replication of a (+)RNA Virus. | 2015 | Viruses | pmid:26131959 |
Okamoto Y et al. | Enzymatic formation of anandamide. | 2009 | Vitam. Horm. | pmid:19647106 |
Wu B et al. | [In vivo replacement of phosphatidylethanolamine by phosphatidylcholine affects biological function of E. coli]. | 2010 | Wei Sheng Wu Xue Bao | pmid:21268895 |
Wang J et al. | [Infection with hepatitis B virus enhances basal autophagy]. | 2010 | Wei Sheng Wu Xue Bao | pmid:21365919 |
Nakano M | [Disk-like complex formation by apolipoprotein-lipid membrane interaction and relevance to high-density lipoprotein formation]. | 2008 | Yakugaku Zasshi | pmid:18451614 |
MILSTONE JH | Bovine serum as a complement for the combined effects of thrombokinase and cephalin. | 1952 | Yale J Biol Med | pmid:13015949 |
Zhang N et al. | [The enhancing effect of tomato lectin modified liposomes of insulin on oral absorption in mice]. | 2004 | Yao Xue Xue Bao | pmid:15338884 |
Zhang N et al. | [Enhancing effect of Ulex europaeus agglutinin I modified liposomes on oral insulin absorption in mice]. | 2004 | Yao Xue Xue Bao | pmid:15813031 |
Hasim S et al. | Influence of phosphatidylserine and phosphatidylethanolamine on farnesol tolerance in Candida albicans. | 2018 | Yeast | pmid:29143357 |
Redón M et al. | Effect of low temperature upon vitality of Saccharomyces cerevisiae phospholipid mutants. | 2012 | Yeast | pmid:23027642 |
Tosch W et al. | Molecular species of phosphatidylethanolamine from continuous cultures of Saccharomyces pastorianus syn. carlsbergensis strains. | 2006 | Yeast | pmid:16491465 |
Malisiova F et al. | Liposomal formulations from phospholipids of Greek almond oil. Properties and biological activity. | 2004 May-Jun | Z. Naturforsch., C, J. Biosci. | pmid:18998396 |
Li SY et al. | [Cell membrane phospholipid variation and protein kinase C expression effects on hepatic metastasis of large intestinal carcinoma]. | 2004 | Zhonghua Wai Ke Za Zhi | pmid:15009987 |
Fernández-Bussy R et al. | Expression of phosphatidylcholine biosynthetic enzymes during early embryogenesis in the amphibian Bufo arenarum. | 2015 | Zygote | pmid:24229731 |