PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Papo N and Shai Y | Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides. | 2004 | Biochemistry | pmid:15157073 |
Kol MA et al. | Uptake and remodeling of exogenous phosphatidylethanolamine in E. coli. | 2004 | Biochim. Biophys. Acta | pmid:15164768 |
Brown AJ | Of cholesterol-free mice and men. | 2004 | Curr. Opin. Lipidol. | pmid:15166797 |
Demana PH et al. | Incorporation of ovalbumin into ISCOMs and related colloidal particles prepared by the lipid film hydration method. | 2004 | Int J Pharm | pmid:15196631 |
Trajkovic-Bodennec S et al. | Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes. | 2004 Jul-Aug | Blood Cells Mol. Dis. | pmid:15223015 |
Sugi T et al. | Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss. | 2004 | J. Obstet. Gynaecol. Res. | pmid:15238112 |
Boumann HA et al. | The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro. | 2004 | J. Biol. Chem. | pmid:15258140 |
Laurinavicius S et al. | The origin of phospholipids of the enveloped bacteriophage phi6. | 2004 | Virology | pmid:15262506 |
Wang X et al. | A novel human phosphatidylethanolamine-binding protein resists tumor necrosis factor alpha-induced apoptosis by inhibiting mitogen-activated protein kinase pathway activation and phosphatidylethanolamine externalization. | 2004 | J. Biol. Chem. | pmid:15302887 |
Doerrler WT et al. | MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli. | 2004 | J. Biol. Chem. | pmid:15304478 |