PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Xu Z et al. | Synthesis and characterization of oligomaltose-grafted lipids with application to liposomes. | 2002 | J Colloid Interface Sci | pmid:16290762 |
Pacetti D et al. | High performance liquid chromatography-tandem mass spectrometry of phospholipid molecular species in eggs from hens fed diets enriched in seal blubber oil. | 2005 | J Chromatogr A | pmid:16298186 |
Hamai C et al. | Effect of average phospholipid curvature on supported bilayer formation on glass by vesicle fusion. | 2006 | Biophys. J. | pmid:16299084 |
Sou YS et al. | Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16. | 2006 | J. Biol. Chem. | pmid:16303767 |
Manucha W et al. | Effect of losartan pretreatment on kidney lipid content after unilateral obstruction in rats. | 2005 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:16309578 |
Wichmann O et al. | A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16323228 |
Hocquellet A et al. | Evidence for a different metabolism of PC and PE in shoots and roots. | 2005 Oct-Nov | Plant Physiol. Biochem. | pmid:16325411 |
Boumann HA et al. | Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote. | 2006 | Mol. Biol. Cell | pmid:16339082 |
Kim A et al. | Modulation of the specific interaction of cardiolipin with Cytochrome c by Zwitterionic phospholipids in binary mixed bilayers: a 2H and 31P-NMR study. | 2005 | J. Biochem. Mol. Biol. | pmid:16353315 |
Kaliszewski P et al. | Enhanced levels of Pis1p (phosphatidylinositol synthase) improve the growth of Saccharomyces cerevisiae cells deficient in Rsp5 ubiquitin ligase. | 2006 | Biochem. J. | pmid:16363994 |
Sharpley MS et al. | Interactions between phospholipids and NADH:ubiquinone oxidoreductase (complex I) from bovine mitochondria. | 2006 | Biochemistry | pmid:16388600 |
Zhirnov AE et al. | Lipid composition determines interaction of liposome membranes with Pluronic L61. | 2005 | Biochim. Biophys. Acta | pmid:16405999 |
Bourre JM et al. | Fatty acid alterations in liver peroxisomes from n-3-deficient mice. | 2006 | Ann. Nutr. Metab. | pmid:16407648 |
Wachtel E et al. | A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes. | 2006 | Biochemistry | pmid:16430232 |
Blois A et al. | Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. | 2006 | Regul. Pept. | pmid:16445995 |
Alder-Baerens N et al. | Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. | 2006 | Mol. Biol. Cell | pmid:16452632 |
Min Y et al. | A distinctive fatty acid profile in circulating lipids of Korean gestational diabetics: a pilot study. | 2006 | Diabetes Res. Clin. Pract. | pmid:16455150 |
Petelska AD et al. | The interfacial tension of the lipid membrane formed from lipid-cholesterol and lipid-lipid systems. | 2006 | Cell Biochem. Biophys. | pmid:16456222 |
Clark MC et al. | NMR assignment of rat Raf kinase inhibitor protein. | 2006 | J. Biomol. NMR | pmid:16456706 |
Singh AT et al. | Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. | 2005 | Lipids | pmid:16459925 |