PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Cataract D002386 34 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Trypanosomiasis D014352 5 associated lipids
Melanoma D008545 69 associated lipids
Weight Gain D015430 101 associated lipids
Thrombosis D013927 49 associated lipids
Alzheimer Disease D000544 76 associated lipids
Myocardial Ischemia D017202 11 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Psoriasis D011565 47 associated lipids
Epilepsy D004827 35 associated lipids
Galactosemias D005693 5 associated lipids
Toxoplasmosis D014123 9 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Trematode Infections D014201 8 associated lipids
Tangier Disease D013631 8 associated lipids
Abortion, Habitual D000026 5 associated lipids
Choline Deficiency D002796 16 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Bacteremia D016470 9 associated lipids
Cholestasis, Intrahepatic D002780 4 associated lipids
Thinness D013851 11 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Hyperhomocysteinemia D020138 6 associated lipids
Venous Thrombosis D020246 11 associated lipids
Hamartoma Syndrome, Multiple D006223 1 associated lipids
Sneddon Syndrome D018860 1 associated lipids
Activated Protein C Resistance D020016 1 associated lipids
Venous Thromboembolism D054556 2 associated lipids
Chondrodysplasia Punctata, Rhizomelic D018902 4 associated lipids
Iron Overload D019190 11 associated lipids
Barth Syndrome D056889 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Wang J et al. Plasma lipidomic signatures of spontaneous obese rhesus monkeys. 2019 Lipids Health Dis pmid:30621707
Lee SA et al. Chryseolinea soli sp. nov., isolated from soil. 2019 J. Microbiol. pmid:30706341
Phurbu D et al. Flavobacterium tibetense sp. nov., isolated from a wetland. 2019 Int. J. Syst. Evol. Microbiol. pmid:30457510
Jung MY et al. Paraburkholderia dokdonella sp. nov., isolated from a plant from the genus Campanula. 2019 J. Microbiol. pmid:30456756
Lee H et al. Flavisolibacter aluminii sp. nov., a novel member of the genus Flavisolibacter isolated from an automotive air conditioning system. 2019 J. Microbiol. pmid:30456752
Chaudhary DK et al. Flavobacterium dasani sp. nov., a psychrotolerant bacterium isolated from Arctic soil. 2019 Arch. Microbiol. pmid:30238204
Romanenko LA et al. Winogradskyella profunda sp. nov. isolated from the Chukchi Sea bottom sediments. 2019 Arch. Microbiol. pmid:30187095
Akhberdi O et al. Roles of phospholipid methyltransferases in pycnidia development, stress tolerance and secondary metabolism in the taxol-producing fungus Pestalotiopsis microspore. 2018 Microbiol. Res. pmid:29625656
Mioka T et al. Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane. 2018 Mol. Biol. Cell pmid:29540528
Fajardo VA et al. Elevated whole muscle phosphatidylcholine: phosphatidylethanolamine ratio coincides with reduced SERCA activity in murine overloaded plantaris muscles. 2018 Lipids Health Dis pmid:29534725
Yu CY et al. Membrane glycerolipid equilibrium under endoplasmic reticulum stress in Arabidopsis thaliana. 2018 Biochem. Biophys. Res. Commun. pmid:29524407
Burger HM et al. Modulation of key lipid raft constituents in primary rat hepatocytes by fumonisin B - Implications for cancer promotion in the liver. 2018 Food Chem. Toxicol. pmid:29510220
Le Pogam P et al. Untargeted Metabolomics Reveal Lipid Alterations upon 2-Deoxyglucose Treatment in Human HaCaT Keratinocytes. 2018 J. Proteome Res. pmid:29430917
Li W et al. Spirosoma pomorum sp. nov., isolated from apple orchard soil. 2018 J. Microbiol. pmid:29392558
Beer KB et al. Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry. 2018 Proc. Natl. Acad. Sci. U.S.A. pmid:29367422
Li L et al. Limoniibacter endophyticus gen. nov., sp. nov., an alphaproteobacterium isolated from the roots of Limonium otolepis. 2018 Arch. Microbiol. pmid:29356837
Dahal RH and Kim J Chitinophaga caseinilytica sp. nov., a casein hydrolysing bacterium isolated from forest soil. 2018 Arch. Microbiol. pmid:29350245
Montaner A et al. Specific Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cells. 2018 Sci Rep pmid:29323239
Lee JB et al. Larkinella roseus sp. nov., a species of the family Cytophagaceae isolated from beach soil. 2018 J. Microbiol. pmid:29299846
Hasim S et al. Influence of phosphatidylserine and phosphatidylethanolamine on farnesol tolerance in Candida albicans. 2018 Yeast pmid:29143357
Basu Ball W et al. The role of nonbilayer phospholipids in mitochondrial structure and function. 2018 FEBS Lett. pmid:29067684
Graessler J et al. Urinary Lipidomics: evidence for multiple sources and sexual dimorphism in healthy individuals. 2018 Pharmacogenomics J. pmid:28607507
Samdani GK et al. Impact of Phospholipids and Tocopherols on the Oxidative Stability of Soybean Oil-in-Water Emulsions. 2018 J. Agric. Food Chem. pmid:29629560
Tang L et al. Roseicyclus marinus sp. nov., isolated from a Synechococcus culture, and emended description of the genus Roseicyclus. 2018 Int. J. Syst. Evol. Microbiol. pmid:29620503
Liu Q et al. Flavobacterium hankyongi sp. nov., isolated from activated sludge. 2018 Int. J. Syst. Evol. Microbiol. pmid:29620495
Franco A et al. Winogradskyella pocilloporae sp. nov. isolated from healthy tissue of the coral Pocillopora damicornis. 2018 Int. J. Syst. Evol. Microbiol. pmid:29620493
Wang NN et al. Aquimarina celericrescens sp. nov., isolated from seawater. 2018 Int. J. Syst. Evol. Microbiol. pmid:29580323
Choi S et al. Dokdonia aurantiaca sp. nov., isolated from seaweed Zostera marina. 2018 Int. J. Syst. Evol. Microbiol. pmid:29570445
Sharma A et al. Subsaxibacter sediminis sp. nov., isolated from Arctic glacial sediment and emended description of the genus Subsaxibacter. 2018 Int. J. Syst. Evol. Microbiol. pmid:29561259
Zhao JC et al. Flavobacterium artemisiae sp. nov., isolated from the rhizosphere of Artemisia annua L. and emended descriptions of Flavobacterium compostarboris and Flavobacterium procerum. 2018 Int. J. Syst. Evol. Microbiol. pmid:29547095
Shin SK et al. Tenacibaculum todarodis sp. nov., isolated from a squid. 2018 Int. J. Syst. Evol. Microbiol. pmid:29521615
Park S et al. Pseudobizionia ponticola gen. nov., sp. nov., isolated from seawater. 2018 Int. J. Syst. Evol. Microbiol. pmid:29521613
Kwon YM et al. Euzebyella algicola sp. nov., a marine bacterium of the family Flavobacteriaceae, isolated from green algae. 2018 Int. J. Syst. Evol. Microbiol. pmid:29458477
Park S et al. Thalassotalea insulae sp. nov., isolated from tidal flat sediment. 2018 Int. J. Syst. Evol. Microbiol. pmid:29488866
Ren Q et al. Flavobacterium ovatum sp. nov., a marine bacterium isolated from an Antarctic intertidal sandy beach. 2018 Int. J. Syst. Evol. Microbiol. pmid:29458470
Chaudhary DK and Kim J Chitinophaga humicola sp. nov., isolated from oil-contaminated soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29458467
Li AZ et al. Arenibacter catalasegens sp. nov., isolated from marine surface sediment, and emended description of the genus Arenibacter. 2018 Int. J. Syst. Evol. Microbiol. pmid:29458460
Jiang F et al. Hymenobacter rubripertinctus sp. nov., isolated from Antarctic tundra soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29388548
Friedman JR et al. Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER. 2018 Dev. Cell pmid:29290583
Christiansen L et al. Colwellia echini sp. nov., an agar- and carrageenan-solubilizing bacterium isolated from sea urchin. 2018 Int. J. Syst. Evol. Microbiol. pmid:29388544
Vasquez-Montes V et al. Comparison of lipid-dependent bilayer insertion of pHLIP and its P20G variant. 2018 Biochim. Biophys. Acta pmid:29138065
Park S et al. Jannaschia confluentis sp. nov., isolated from the junction between the ocean and a freshwater spring. 2018 Int. J. Syst. Evol. Microbiol. pmid:29388543
Takaoka R et al. Formation of asymmetric vesicles via phospholipase D-mediated transphosphatidylation. 2018 Biochim. Biophys. Acta pmid:29032301
Kaur M et al. Sphingobacterium bovisgrunnientis sp. nov., isolated from yak milk. 2018 Int. J. Syst. Evol. Microbiol. pmid:29388539
Schick M Strongly Correlated Rafts in Both Leaves of an Asymmetric Bilayer. 2018 J Phys Chem B pmid:29024593
Frudd K et al. Oxidation of Atg3 and Atg7 mediates inhibition of autophagy. 2018 Nat Commun pmid:29311554
Park S et al. Flavobacterium sediminilitoris sp. nov., isolated from a tidal flat. 2018 Int. J. Syst. Evol. Microbiol. pmid:29303697
Bu JH and Cha CJ Flavobacterium foetidum sp. nov., isolated from ginseng soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29303696
Chaudhary DK and Kim J Sphingobacterium terrae sp. nov., isolated from oil-contaminated soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29303695
Nedashkovskaya OI et al. Polaribacter staleyi sp. nov., a polysaccharide-degrading marine bacterium isolated from the red alga Ahnfeltia tobuchiensis. 2018 Int. J. Syst. Evol. Microbiol. pmid:29303693
Jeon J et al. Larkinella knui sp. nov., isolated from soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29300161
Kim DU et al. Spirosoma metallum sp. nov., isolated from an automobile air conditioning system. 2018 Arch. Microbiol. pmid:28799031
Wang Y et al. Thalassotalea atypica sp. nov., isolated from seawater, and emended description of Thalassotalea eurytherma. 2018 Int. J. Syst. Evol. Microbiol. pmid:29143725
Chaudhary DK et al. Nemorella caseinilytica gen. nov., sp. nov., isolated from forest soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29139350
Villamil-Ortiz JG et al. Differential Pattern of Phospholipid Profile in the Temporal Cortex from E280A-Familiar and Sporadic Alzheimer's Disease Brains. 2018 J. Alzheimers Dis. pmid:29125487
Bolognesi G et al. Sculpting and fusing biomimetic vesicle networks using optical tweezers. 2018 Nat Commun pmid:29760422
Bartelds R et al. Niosomes, an alternative for liposomal delivery. 2018 PLoS ONE pmid:29649223
Vazquez-de-Lara LG et al. Phosphatidylethanolamine Induces an Antifibrotic Phenotype in Normal Human Lung Fibroblasts and Ameliorates Bleomycin-Induced Lung Fibrosis in Mice. 2018 Int J Mol Sci pmid:30223424
Cho ES et al. Zunongwangia flava sp. nov., belonging to the family Flavobacteriaceae, isolated from Salicornia europaea. 2018 J. Microbiol. pmid:30361977
Admasu TD et al. Lipid profiling of C. elegans strains administered pro-longevity drugs and drug combinations. 2018 Sci Data pmid:30351306
Lin D et al. Alteromonas indica sp. nov., isolated from surface seawater from the Indian Ocean. 2018 Int. J. Syst. Evol. Microbiol. pmid:30351269
Shetty SA et al. Reclassification of Eubacterium hallii as Anaerobutyricum hallii gen. nov., comb. nov., and description of Anaerobutyricum soehngenii sp. nov., a butyrate and propionate-producing bacterium from infant faeces. 2018 Int. J. Syst. Evol. Microbiol. pmid:30351260
Wallner S et al. Phosphatidylcholine and phosphatidylethanolamine plasmalogens in lipid loaded human macrophages. 2018 PLoS ONE pmid:30308051
Zhang LL et al. Pedobacter chitinilyticus sp. nov., a chitin-degrading bacterium isolated from wheat leaf tissue. 2018 Int. J. Syst. Evol. Microbiol. pmid:30307389
Song L et al. Alcanivorax indicus sp. nov., isolated from seawater. 2018 Int. J. Syst. Evol. Microbiol. pmid:30307386
He RH et al. Hanstruepera crassostreae sp. nov., a novel marine bacterium of the family Flavobacteriaceae isolated from an oyster. 2018 Int. J. Syst. Evol. Microbiol. pmid:30303476
Miyata N et al. Porin proteins have critical functions in mitochondrial phospholipid metabolism in yeast. 2018 J. Biol. Chem. pmid:30237174
Wang JJ et al. Chryseolinea flava sp. nov., a new species of Chryseolinea isolated from soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:30222097
Lee DW et al. Maribacter litoralis sp. nov. a marine bacterium isolated from seashore. 2018 Int. J. Syst. Evol. Microbiol. pmid:30222095
Luo HR et al. Brumimicrobium salinarum sp. nov., isolated from a marine solar saltern. 2018 Int. J. Syst. Evol. Microbiol. pmid:30222094
Zhou S et al. Abyssibacter profundi gen. nov., sp. nov., a marine bacterium isolated from seawater of the Mariana Trench. 2018 Int. J. Syst. Evol. Microbiol. pmid:30204582
Liu Q et al. Flavipsychrobacter stenotrophus gen. nov., sp. nov., a novel member of the phylum Bacteroidetes isolated from a glacier. 2018 Int. J. Syst. Evol. Microbiol. pmid:30168791
Van Le V et al. Sphingobacterium praediipecoris sp. nov. isolated from effluent of a dairy manure treatment plant. 2018 Arch. Microbiol. pmid:30159757
Song J et al. Winogradskyella aurantiaca sp. nov., isolated from seawater. 2018 Int. J. Syst. Evol. Microbiol. pmid:30156531
Osman G et al. Pontibacter silvestris sp. nov., isolated from the soil of a Populus euphratica forest and emended description of the genus Pontibacter. 2018 Int. J. Syst. Evol. Microbiol. pmid:30141769
Choi J et al. Aestuariibaculum marinum sp. nov., a marine bacterium isolated from seawater in South Korea. 2018 J. Microbiol. pmid:30141155
Wang C et al. Winogradskyella tangerina sp. nov., a member of the Flavobacteriaceae isolated from coastal sediment. 2018 Int. J. Syst. Evol. Microbiol. pmid:30010527
Shirouchi B et al. Quantities of Phospholipid Molecular Classes in Japanese Meals and Prediction of Their Sources by Multiple Regression Analysis. 2018 J. Nutr. Sci. Vitaminol. pmid:29962433
Ten LN et al. Hymenobacter jeollabukensis sp. nov., isolated from soil. 2018 J. Microbiol. pmid:29956123
Ren TT et al. Flavihumibacter profundi sp. nov., isolated from eutrophic freshwater sediment. 2018 J. Microbiol. pmid:29956122
Yoon J et al. Spongiibacterium fuscum sp. nov., a marine Flavobacteriaceae isolated from the hard coral Galaxea fascicularis. 2018 Arch. Microbiol. pmid:29955925
Nguyen TM et al. Proposal of three novel species of soil bacteria, Variovorax ureilyticus, Variovorax rhizosphaerae, and Variovorax robiniae, in the family Comamonadaceae. 2018 J. Microbiol. pmid:29948826
Joung Y et al. Pedobacter aquicola sp. nov., isolated from freshwater. 2018 J. Microbiol. pmid:29948823
Choi J et al. Thalassorhabdus aurantiaca gen. nov., sp. nov., a new member of the family Flavobacteriaceae isolated from seawater in South Korea. 2018 Antonie Van Leeuwenhoek pmid:29948434
Siddiqi MZ et al. Olivibacter ginsenosidimutans sp nov., with ginsenoside converting activity isolated from compost, and reclassification of Pseudosphingobacterium domesticum as Olivibacter domesticus comb. nov. 2018 Int. J. Syst. Evol. Microbiol. pmid:29944109
Liu SQ et al. Muricauda iocasae sp. nov., isolated from deep sea sediment of the South China Sea. 2018 Int. J. Syst. Evol. Microbiol. pmid:29932387
Wei Y et al. Pseudomonas abyssi sp. nov., isolated from the abyssopelagic water of the Mariana Trench. 2018 Int. J. Syst. Evol. Microbiol. pmid:29927369
Wei Y et al. Pedobacter yulinensis sp. nov., isolated from sandy soil, and emended description of the genus Pedobacter. 2018 Int. J. Syst. Evol. Microbiol. pmid:29927365
Kang H et al. Maribacter maritimus sp. nov., isolated from seawater. 2018 Int. J. Syst. Evol. Microbiol. pmid:29893666
Kawanishi N et al. Effects of aging on serum levels of lipid molecular species as determined by lipidomics analysis in Japanese men and women. 2018 Lipids Health Dis pmid:29875018
Mutlu Agardan NB et al. Redox-triggered intracellular siRNA delivery. 2018 Chem. Commun. (Camb.) pmid:29869650
Shin SK et al. Gramella salexigens sp. nov., isolated from seawater. 2018 Int. J. Syst. Evol. Microbiol. pmid:29851376
Lappalainen M et al. Novel Biomarker Candidates for Febrile Neutropenia in Hematological Patients Using Nontargeted Metabolomics. 2018 Dis. Markers pmid:29849825
Billeaud C et al. Effects on Fatty Acid Metabolism of a New Powdered Human Milk Fortifier Containing Medium-Chain Triacylglycerols and Docosahexaenoic Acid in Preterm Infants. 2018 Nutrients pmid:29843467
Che H et al. A comparative study of EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine on Aβ induced cognitive deficiency in a rat model of Alzheimer's disease. 2018 Food Funct pmid:29774334
Lim SJ et al. Hymenobacter pedocola sp. nov., a novel bacterium isolated from soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29767618
Yao HY and Xue HW Phosphatidic acid plays key roles regulating plant development and stress responses. 2018 J Integr Plant Biol pmid:29660254
Wang FQ et al. Carboxylicivirga sediminis sp. nov., isolated from coastal sediment. 2018 Int. J. Syst. Evol. Microbiol. pmid:29658858
Pini T et al. Binder of Sperm Proteins protect ram spermatozoa from freeze-thaw damage. 2018 Cryobiology pmid:29653077
Bradley RM et al. Lpaatδ/Agpat4 deficiency impairs maximal force contractility in soleus and alters fibre type in extensor digitorum longus muscle. 2018 Biochim Biophys Acta Mol Cell Biol Lipids pmid:29627383