PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Cataract D002386 34 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Trypanosomiasis D014352 5 associated lipids
Melanoma D008545 69 associated lipids
Weight Gain D015430 101 associated lipids
Thrombosis D013927 49 associated lipids
Alzheimer Disease D000544 76 associated lipids
Myocardial Ischemia D017202 11 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Psoriasis D011565 47 associated lipids
Epilepsy D004827 35 associated lipids
Galactosemias D005693 5 associated lipids
Toxoplasmosis D014123 9 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Trematode Infections D014201 8 associated lipids
Tangier Disease D013631 8 associated lipids
Abortion, Habitual D000026 5 associated lipids
Choline Deficiency D002796 16 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Bacteremia D016470 9 associated lipids
Cholestasis, Intrahepatic D002780 4 associated lipids
Thinness D013851 11 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Hyperhomocysteinemia D020138 6 associated lipids
Venous Thrombosis D020246 11 associated lipids
Hamartoma Syndrome, Multiple D006223 1 associated lipids
Sneddon Syndrome D018860 1 associated lipids
Activated Protein C Resistance D020016 1 associated lipids
Venous Thromboembolism D054556 2 associated lipids
Chondrodysplasia Punctata, Rhizomelic D018902 4 associated lipids
Iron Overload D019190 11 associated lipids
Barth Syndrome D056889 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Fajardo VA et al. Elevated whole muscle phosphatidylcholine: phosphatidylethanolamine ratio coincides with reduced SERCA activity in murine overloaded plantaris muscles. 2018 Lipids Health Dis pmid:29534725
Yu CY et al. Membrane glycerolipid equilibrium under endoplasmic reticulum stress in Arabidopsis thaliana. 2018 Biochem. Biophys. Res. Commun. pmid:29524407
Shin SK et al. Tenacibaculum todarodis sp. nov., isolated from a squid. 2018 Int. J. Syst. Evol. Microbiol. pmid:29521615
Park S et al. Flavobacterium sediminilitoris sp. nov., isolated from a tidal flat. 2018 Int. J. Syst. Evol. Microbiol. pmid:29303697
Bu JH and Cha CJ Flavobacterium foetidum sp. nov., isolated from ginseng soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29303696
Chaudhary DK and Kim J Sphingobacterium terrae sp. nov., isolated from oil-contaminated soil. 2018 Int. J. Syst. Evol. Microbiol. pmid:29303695
Liu Q et al. Flavipsychrobacter stenotrophus gen. nov., sp. nov., a novel member of the phylum Bacteroidetes isolated from a glacier. 2018 Int. J. Syst. Evol. Microbiol. pmid:30168791
Van Le V et al. Sphingobacterium praediipecoris sp. nov. isolated from effluent of a dairy manure treatment plant. 2018 Arch. Microbiol. pmid:30159757
Shin SK et al. Gramella salexigens sp. nov., isolated from seawater. 2018 Int. J. Syst. Evol. Microbiol. pmid:29851376
Lappalainen M et al. Novel Biomarker Candidates for Febrile Neutropenia in Hematological Patients Using Nontargeted Metabolomics. 2018 Dis. Markers pmid:29849825