| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Sehayek E et al. | Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol. | 2003 | J. Lipid Res. | pmid:12810817 |
| Prades J et al. | Effects of unsaturated fatty acids and triacylglycerols on phosphatidylethanolamine membrane structure. | 2003 | J. Lipid Res. | pmid:12810821 |
| Noga AA and Vance DE | Insights into the requirement of phosphatidylcholine synthesis for liver function in mice. | 2003 | J. Lipid Res. | pmid:12837848 |
| Schaur RJ | Basic aspects of the biochemical reactivity of 4-hydroxynonenal. | 2003 Aug-Oct | Mol. Aspects Med. | pmid:12892992 |
| MILSTONE JH | Bovine serum as a complement for the combined effects of thrombokinase and cephalin. | 1952 | Yale J Biol Med | pmid:13015949 |
| BAER E et al. | Migration during hydrolysis of esters of glycerophosphoric acid. III. Cephalin and glycerylphosphorylethanolamine. | 1953 | J. Biol. Chem. | pmid:13034779 |
| NORMAN JM and DAWSON RM | A method for measuring the deposition of 32P in phosphatidylethanolamine and its application to rat-brain tissue. | 1953 | Biochem. J. | pmid:13058914 |
| AXELROD J et al. | The direct determination of phosphatidyl ethanolamine and phosphatidyl serine in plasma and red blood cells. | 1953 | J. Biol. Chem. | pmid:13117868 |
| DIECKMANN WJ and POTTINGER RE | Serial studies of the cephalin flocculation and thymol turbidity tests in pregnant patients. | 1954 | Am. J. Obstet. Gynecol. | pmid:13207248 |
| MILSTONE JH | Effect of blood thrombokinase, as influenced by soy bean trypsin inhibitor, ultracentrifugation, and accessory factors. | 1955 | J. Gen. Physiol. | pmid:13242762 |
| O'BRIEN JR | The similarity of the action of phosphatidyl-ethanolamine and platelets in blood coagulation. | 1956 | J. Clin. Pathol. | pmid:13306791 |
| MCCANDLESS EL and ZILVERSMIT DB | The effect of cholesterol on the turnover of lecithin, cephalin and sphingomyelin in the rabbit. | 1956 | Arch. Biochem. Biophys. | pmid:13328128 |
| ROBINSON DS and POOLE JC | The similar effect of chylomicra and ethanolamine phosphatide on the generation of thrombin during coagulation. | 1956 | Q J Exp Physiol Cogn Med Sci | pmid:13485325 |
| POOLE JC and ROBINSON DS | Further observations on the effects of ethanolamine phosphatide on plasma coagulation. | 1956 | Q J Exp Physiol Cogn Med Sci | pmid:13485345 |
| HAWKE JC | The fatty acids of phosphatidylethanolamine and phosphatidylcholine from hen's egg. | 1959 | Biochem. J. | pmid:13638270 |
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| GOBBI F and STEFANINI M | Circulating anti-AHG anticoagulant in a patient with lupus erythematosus disseminatus. Effect of a cephalin complex in vivo. | 1962 | Acta Haematol. | pmid:13899358 |
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| ANSELL GB and SPANNER S | The occurence of a long-chain ether analogue of phosphatidylethanolamine in brain tissue. | 1963 | Biochem. J. | pmid:14013279 |
| CRUZ WO et al. | HAEMOSTATIC ACTIVITY OF CRUDE CEPHALIN COMPONENTS. | 1963 | Br. J. Haematol. | pmid:14076124 |
| ROBINS DC | PHOSPHATIDYLETHANOLAMINE AND LYSOPHOSPHATIDYLETHANOLAMINE. | 1963 | J. Pharm. Pharmacol. | pmid:14079614 |
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