| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Garcia-Manyes S et al. | Effect of ion-binding and chemical phospholipid structure on the nanomechanics of lipid bilayers studied by force spectroscopy. | 2005 | Biophys. J. | pmid:15980180 |
| Park EJ et al. | Dietary ganglioside and long-chain polyunsaturated fatty acids increase ganglioside GD3 content and alter the phospholipid profile in neonatal rat retina. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:15980250 |
| Kalashnikova LA et al. | [Anti-phosphatidylethanolamine antibodies in patients with Sneddon's syndrome]. | 2005 | Klin Med (Mosk) | pmid:15984583 |
| Suits F et al. | Molecular dynamics investigation of the structural properties of phosphatidylethanolamine lipid bilayers. | 2005 | J Chem Phys | pmid:16035800 |
| Pitman MC et al. | Molecular dynamics investigation of dynamical properties of phosphatidylethanolamine lipid bilayers. | 2005 | J Chem Phys | pmid:16035801 |
| Gohil VM et al. | Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae. | 2005 | J. Biol. Chem. | pmid:16036913 |
| Bonner PJ et al. | The Dif chemosensory pathway is directly involved in phosphatidylethanolamine sensory transduction in Myxococcus xanthus. | 2005 | Mol. Microbiol. | pmid:16102016 |
| Song H et al. | Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16105858 |
| Hiraoka M et al. | Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues. | 2005 | J. Lipid Res. | pmid:16106046 |
| Tsukamoto K et al. | Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. | 2005 | J. Biol. Chem. | pmid:16115873 |
| Nakagawa K et al. | Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes. | 2005 | J. Lipid Res. | pmid:16150834 |
| Funari SS et al. | Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes. | 2005 Jul-Aug | Mol. Membr. Biol. | pmid:16154902 |
| Emoto K et al. | Local change in phospholipid composition at the cleavage furrow is essential for completion of cytokinesis. | 2005 | J. Biol. Chem. | pmid:16162509 |
| Kuliszkiewicz-Janus M et al. | 31P MRS analysis of the phospholipid composition of normal human peripheral blood mononuclear cells (PBMC). | 2005 | Cell. Mol. Biol. Lett. | pmid:16217549 |
| Kolomytseva MP et al. | [Heterogeneity of Rhodococcus opacus 1CP as a response to stress induced by chlorophenols]. | 2005 Sep-Oct | Prikl. Biokhim. Mikrobiol. | pmid:16240653 |
| Merino-Montero S et al. | Effects of lactose permease of Escherichia coli on the anisotropy and electrostatic surface potential of liposomes. | 2006 | Biophys. Chem. | pmid:16242835 |
| Marinetti GV | Arrangement of phosphatidylserine and phosphatidylethanolamine in the erythrocyte membrane. | 1977 | Biochim. Biophys. Acta | pmid:16250335 |
| Carmieli R et al. | Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes. | 2006 | Biophys. J. | pmid:16258052 |
| Lins L et al. | "De novo" design of peptides with specific lipid-binding properties. | 2006 | Biophys. J. | pmid:16275638 |
| Müller H et al. | A diet rich in phosphatidylethanolamine increases plasma homocysteine in mink: a comparison with a soybean oil diet. | 2005 | Br. J. Nutr. | pmid:16277769 |