| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Otzen DE et al. | Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition. | 2012 | Biochim. Biophys. Acta | pmid:21920348 |
| Quinn PJ | The structure of complexes between phosphatidylethanolamine and glucosylceramide: a matrix for membrane rafts. | 2011 | Biochim. Biophys. Acta | pmid:21924237 |
| Garrett TA et al. | Non-enzymatically derived minor lipids found in Escherichia coli lipid extracts. | 2011 | Biochim. Biophys. Acta | pmid:21925285 |
| Vance JE | MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond. | 2014 | Biochim. Biophys. Acta | pmid:24316057 |
| Suárez-Germà C et al. | Effect of lactose permease presence on the structure and nanomechanics of two-component supported lipid bilayers. | 2014 | Biochim. Biophys. Acta | pmid:24316189 |
| Sarabipour S et al. | Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation. | 2015 | Biochim. Biophys. Acta | pmid:25896659 |
| Matsuki H et al. | Thermotropic and barotropic phase transitions on diacylphosphatidylethanolamine bilayer membranes. | 2017 | Biochim. Biophys. Acta | pmid:28366514 |
| Ikon N and Ryan RO | Cardiolipin and mitochondrial cristae organization. | 2017 | Biochim. Biophys. Acta | pmid:28336315 |
| Mengistu DH et al. | Ionization properties of mixed lipid membranes: a Gouy-Chapman model of the electrostatic-hydrogen bond switch. | 2011 | Biochim. Biophys. Acta | pmid:21406179 |
| Deng X et al. | iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling. | 2016 | Biochim. Biophys. Acta | pmid:26873633 |
| Marinetti GV | Arrangement of phosphatidylserine and phosphatidylethanolamine in the erythrocyte membrane. | 1977 | Biochim. Biophys. Acta | pmid:16250335 |
| Tatsuta T and Langer T | Intramitochondrial phospholipid trafficking. | 2017 | Biochim. Biophys. Acta | pmid:27542541 |
| López-Revuelta A et al. | Increase in vulnerability to oxidative damage in cholesterol-modified erythrocytes exposed to t-BuOOH. | 2005 | Biochim. Biophys. Acta | pmid:15866485 |
| Danevcic T et al. | Effects of lipid composition on the membrane activity and lipid phase behaviour of Vibrio sp. DSM14379 cells grown at various NaCl concentrations. | 2005 | Biochim. Biophys. Acta | pmid:15878424 |
| Opekarová M et al. | Differential effect of phosphatidylethanolamine depletion on raft proteins: further evidence for diversity of rafts in Saccharomyces cerevisiae. | 2005 | Biochim. Biophys. Acta | pmid:15904666 |
| Arouri A et al. | Peptide induced demixing in PG/PE lipid mixtures: a mechanism for the specificity of antimicrobial peptides towards bacterial membranes? | 2009 | Biochim. Biophys. Acta | pmid:19118516 |
| Reichel M et al. | Alterations of plasma glycerophospholipid and sphingolipid species in male alcohol-dependent patients. | 2015 | Biochim. Biophys. Acta | pmid:26291032 |
| Ibarguren M et al. | Quantitation of cholesterol incorporation into extruded lipid bilayers. | 2010 | Biochim. Biophys. Acta | pmid:20537979 |
| Deng L et al. | Incorporation and remodeling of phosphatidylethanolamine containing short acyl residues in yeast. | 2010 | Biochim. Biophys. Acta | pmid:20176132 |
| Strömstedt AA et al. | Selective membrane disruption by the cyclotide kalata B7: complex ions and essential functional groups in the phosphatidylethanolamine binding pocket. | 2016 | Biochim. Biophys. Acta | pmid:26878982 |