| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xu Z et al. | Synthesis and characterization of oligomaltose-grafted lipids with application to liposomes. | 2002 | J Colloid Interface Sci | pmid:16290762 |
| Pacetti D et al. | High performance liquid chromatography-tandem mass spectrometry of phospholipid molecular species in eggs from hens fed diets enriched in seal blubber oil. | 2005 | J Chromatogr A | pmid:16298186 |
| Hamai C et al. | Effect of average phospholipid curvature on supported bilayer formation on glass by vesicle fusion. | 2006 | Biophys. J. | pmid:16299084 |
| Sou YS et al. | Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16. | 2006 | J. Biol. Chem. | pmid:16303767 |
| Manucha W et al. | Effect of losartan pretreatment on kidney lipid content after unilateral obstruction in rats. | 2005 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:16309578 |
| Wichmann O et al. | A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16323228 |
| Hocquellet A et al. | Evidence for a different metabolism of PC and PE in shoots and roots. | 2005 Oct-Nov | Plant Physiol. Biochem. | pmid:16325411 |
| Boumann HA et al. | Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote. | 2006 | Mol. Biol. Cell | pmid:16339082 |
| Kim A et al. | Modulation of the specific interaction of cardiolipin with Cytochrome c by Zwitterionic phospholipids in binary mixed bilayers: a 2H and 31P-NMR study. | 2005 | J. Biochem. Mol. Biol. | pmid:16353315 |
| Kaliszewski P et al. | Enhanced levels of Pis1p (phosphatidylinositol synthase) improve the growth of Saccharomyces cerevisiae cells deficient in Rsp5 ubiquitin ligase. | 2006 | Biochem. J. | pmid:16363994 |
| Sharpley MS et al. | Interactions between phospholipids and NADH:ubiquinone oxidoreductase (complex I) from bovine mitochondria. | 2006 | Biochemistry | pmid:16388600 |
| Zhirnov AE et al. | Lipid composition determines interaction of liposome membranes with Pluronic L61. | 2005 | Biochim. Biophys. Acta | pmid:16405999 |
| Bourre JM et al. | Fatty acid alterations in liver peroxisomes from n-3-deficient mice. | 2006 | Ann. Nutr. Metab. | pmid:16407648 |
| Wachtel E et al. | A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes. | 2006 | Biochemistry | pmid:16430232 |
| Blois A et al. | Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. | 2006 | Regul. Pept. | pmid:16445995 |
| Alder-Baerens N et al. | Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. | 2006 | Mol. Biol. Cell | pmid:16452632 |
| Min Y et al. | A distinctive fatty acid profile in circulating lipids of Korean gestational diabetics: a pilot study. | 2006 | Diabetes Res. Clin. Pract. | pmid:16455150 |
| Petelska AD et al. | The interfacial tension of the lipid membrane formed from lipid-cholesterol and lipid-lipid systems. | 2006 | Cell Biochem. Biophys. | pmid:16456222 |
| Clark MC et al. | NMR assignment of rat Raf kinase inhibitor protein. | 2006 | J. Biomol. NMR | pmid:16456706 |
| Singh AT et al. | Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. | 2005 | Lipids | pmid:16459925 |