| MeSH term | MeSH ID | Detail |
|---|---|---|
| Liver Failure, Acute | D017114 | 11 associated lipids |
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Choline Deficiency | D002796 | 16 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Mammary Neoplasms, Animal | D015674 | 27 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Melanoma | D008545 | 69 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:15131978 | ||||
| pmid: | ||||
| Cesari AB et al. | Changes in the lipid composition of Bradyrhizobium cell envelope reveal a rapid response to water deficit involving lysophosphatidylethanolamine synthesis from phosphatidylethanolamine in outer membrane. | Res. Microbiol. | pmid:29864488 | |
| FRISCH AW and QUILLIGAN JJ | A modified cephalin cholesterol test (Hanger) in the study of hepatic disease. | 1946 | Am. J. Med. Sci. | pmid:20996956 |
| Havens WP and Marck RE | A COMPARISON OF THE CEPHALIN-CHOLESTEROL FLOCCULATION AND THYMOL TURBIDITY TESTS IN PATIENTS WITH EXPERIMENTALLY INDUCED INFECTIOUS HEPATITIS. | 1946 | J. Clin. Invest. | pmid:16695379 |
| PRINCE GE | Cephalin-cholesterol flocculation in premature infants and children receiving immune globulin. | 1947 | J. Pediatr. | pmid:20249037 |
| Saifer A | A METHOD FOR THE QUANTITATIVE DETERMINATION OF THE CEPHALIN-CHOLESTEROL FLOCCULATION REACTION. | 1948 | J. Clin. Invest. | pmid:16695596 |
| STEINBERG BL | Intravenous procaine; its effect on liver function in man as determined by the cephalin flocculation test. | 1949 | Anesthesiology | pmid:15393676 |
| SAIFER A | Studies with the quantitative cephalin cholesterol flocculation reaction; effect of variation in temperature at which Hanger reaction occurs; the protein patterns of normal and abnormal liver-disease sera. | 1949 | Bull N Y Acad Med | pmid:18152263 |
| NEEFE JR et al. | Comparison of the thymol, cephalin-cholesterol flocculation and colloidal red tests in acute viral hepatitis. | 1950 | Am. J. Med. | pmid:15413625 |
| CHRISTHILF SM et al. | Liver function during pregnancy and the puerperium, as measured by the cephalin-cholesterol flocculation, the thymol turbidity, and the bromsulfalein tests. | 1950 | Am. J. Obstet. Gynecol. | pmid:15410828 |
| MILSTONE JH | Bovine serum as a complement for the combined effects of thrombokinase and cephalin. | 1952 | Yale J Biol Med | pmid:13015949 |
| AXELROD J et al. | The direct determination of phosphatidyl ethanolamine and phosphatidyl serine in plasma and red blood cells. | 1953 | J. Biol. Chem. | pmid:13117868 |
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| MILSTONE JH | Effect of blood thrombokinase, as influenced by soy bean trypsin inhibitor, ultracentrifugation, and accessory factors. | 1955 | J. Gen. Physiol. | pmid:13242762 |
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