PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Iron Overload D019190 11 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Choline Deficiency D002796 16 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Cataract D002386 34 associated lipids
Epilepsy D004827 35 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Psoriasis D011565 47 associated lipids
Fatty Liver D005234 48 associated lipids
Thrombosis D013927 49 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Melanoma D008545 69 associated lipids
Alzheimer Disease D000544 76 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Weight Gain D015430 101 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
CRUZ WO et al. Crude cephalin as the active substance of organ extracts able to convert venous blood into hemostatic blood. 1959 Arch. Biochem. Biophys. pmid:13813116
GOBBI F and STEFANINI M Circulating anti-AHG anticoagulant in a patient with lupus erythematosus disseminatus. Effect of a cephalin complex in vivo. 1962 Acta Haematol. pmid:13899358
TOBIAS JM et al. Phospholipidcholesterol membrane model. Control of resistance by ions or current flow. 1962 J. Gen. Physiol. pmid:13921460
MERKL I and LANDS WE Metabolism of glycerolipids. IV. Synthesis of phosphatidylethanolamine. 1963 J. Biol. Chem. pmid:13935003
ROBINS DC and THOMAS IL Physico-chemical experiments with phosphatidyl ethanolamine sols. 1963 J. Pharm. Pharmacol. pmid:13974409
SPITZER HL and BALINT JA A rapid quantitative separation of phosphatidyl ethanolamine and phosphatidyl serine by column chromatography. 1963 Anal. Biochem. pmid:13990206
ANSELL GB and SPANNER S The occurence of a long-chain ether analogue of phosphatidylethanolamine in brain tissue. 1963 Biochem. J. pmid:14013279
CRUZ WO et al. HAEMOSTATIC ACTIVITY OF CRUDE CEPHALIN COMPONENTS. 1963 Br. J. Haematol. pmid:14076124
ROBINS DC PHOSPHATIDYLETHANOLAMINE AND LYSOPHOSPHATIDYLETHANOLAMINE. 1963 J. Pharm. Pharmacol. pmid:14079614
ANSELL GB and MARSHALL EF SOME EFFECTS OF CHLORPROMAZINE ON BRAIN PHOSPHOLIPID METABOLISM. II. LABELLING OF CHOLINE- AND ETHANOLAMINE-CONTAINING PHOSPHOLIPIDS BY RADIOACTIVE PRECURSORS IN VITRO. 1963 J. Neurochem. pmid:14087692