| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Tangier Disease | D013631 | 8 associated lipids |
| Thinness | D013851 | 11 associated lipids |
| Thrombosis | D013927 | 49 associated lipids |
| Toxoplasmosis | D014123 | 9 associated lipids |
| Trematode Infections | D014201 | 8 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| O'Donnell VB | Mass spectrometry analysis of oxidized phosphatidylcholine and phosphatidylethanolamine. | 2011 | Biochim. Biophys. Acta | pmid:21835265 |
| Moore DS et al. | Liposomes with diverse compositions are protected during desiccation by LEA proteins from Artemia franciscana and trehalose. | 2016 | Biochim. Biophys. Acta | pmid:26518519 |
| Otzen DE et al. | Lactadherin binds to phosphatidylserine-containing vesicles in a two-step mechanism sensitive to vesicle size and composition. | 2012 | Biochim. Biophys. Acta | pmid:21920348 |
| Epand RM et al. | Molecular mechanisms of membrane targeting antibiotics. | 2016 | Biochim. Biophys. Acta | pmid:26514603 |
| Quinn PJ | The structure of complexes between phosphatidylethanolamine and glucosylceramide: a matrix for membrane rafts. | 2011 | Biochim. Biophys. Acta | pmid:21924237 |
| Vance JE | MAM (mitochondria-associated membranes) in mammalian cells: lipids and beyond. | 2014 | Biochim. Biophys. Acta | pmid:24316057 |
| Suárez-Germà C et al. | Effect of lactose permease presence on the structure and nanomechanics of two-component supported lipid bilayers. | 2014 | Biochim. Biophys. Acta | pmid:24316189 |
| Li Z et al. | A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis. | 2007 | Biochim. Biophys. Acta | pmid:17513168 |
| Cardoso AM et al. | S4(13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: implications for cell internalization. | 2012 | Biochim. Biophys. Acta | pmid:22230348 |
| van der Veen JN et al. | The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease. | 2017 | Biochim. Biophys. Acta | pmid:28411170 |
| Takaoka R et al. | Formation of asymmetric vesicles via phospholipase D-mediated transphosphatidylation. | 2018 | Biochim. Biophys. Acta | pmid:29032301 |
| Matsuki H et al. | Thermotropic and barotropic phase transitions on diacylphosphatidylethanolamine bilayer membranes. | 2017 | Biochim. Biophys. Acta | pmid:28366514 |
| Marinetti GV | Arrangement of phosphatidylserine and phosphatidylethanolamine in the erythrocyte membrane. | 1977 | Biochim. Biophys. Acta | pmid:16250335 |
| Tomioka M et al. | Lysophosphatidylcholine export by human ABCA7. | 2017 | Biochim. Biophys. Acta | pmid:28373057 |
| Willumeit R et al. | Structural rearrangement of model membranes by the peptide antibiotic NK-2. | 2005 | Biochim. Biophys. Acta | pmid:15893515 |
| López-Revuelta A et al. | Increase in vulnerability to oxidative damage in cholesterol-modified erythrocytes exposed to t-BuOOH. | 2005 | Biochim. Biophys. Acta | pmid:15866485 |
| Danevcic T et al. | Effects of lipid composition on the membrane activity and lipid phase behaviour of Vibrio sp. DSM14379 cells grown at various NaCl concentrations. | 2005 | Biochim. Biophys. Acta | pmid:15878424 |
| Carmona-Antoñanzas G et al. | Molecular mechanism of dietary phospholipid requirement of Atlantic salmon, Salmo salar, fry. | 2015 | Biochim. Biophys. Acta | pmid:26303578 |
| Ibarguren M et al. | Quantitation of cholesterol incorporation into extruded lipid bilayers. | 2010 | Biochim. Biophys. Acta | pmid:20537979 |
| Elmes M et al. | The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. | 2004 | Biochim. Biophys. Acta | pmid:15522830 |