PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Schaur RJ Basic aspects of the biochemical reactivity of 4-hydroxynonenal. 2003 Aug-Oct Mol. Aspects Med. pmid:12892992
Boumann HA et al. The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro. 2004 J. Biol. Chem. pmid:15258140
Laurinavicius S et al. The origin of phospholipids of the enveloped bacteriophage phi6. 2004 Virology pmid:15262506
Sugi T et al. Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss. 2004 J. Obstet. Gynaecol. Res. pmid:15238112
Demana PH et al. Incorporation of ovalbumin into ISCOMs and related colloidal particles prepared by the lipid film hydration method. 2004 Int J Pharm pmid:15196631
Papo N and Shai Y Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides. 2004 Biochemistry pmid:15157073
Demana PH et al. A comparison of pseudo-ternary diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by lipid-film hydration and dialysis. 2004 J. Pharm. Pharmacol. pmid:15142333
Zhang WN et al. Separation of phosphatidylcholine and phosphatidylethanolamine by using high-performance displacement chromatography. 2004 J Chromatogr A pmid:15146915
Tasseva G et al. Regulation of phosphatidylcholine biosynthesis under salt stress involves choline kinases in Arabidopsis thaliana. 2004 FEBS Lett. pmid:15147879
Sprott GD et al. Liposome adjuvants prepared from the total polar lipids of Haloferax volcanii, Planococcus spp. and Bacillus firmus differ in ability to elicit and sustain immune responses. 2004 Vaccine pmid:15149772
Yang YW et al. The apoptotic and necrotic effects of tomatine adjuvant. 2004 Vaccine pmid:15149791
Lukyanov AN and Torchilin VP Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. 2004 Adv. Drug Deliv. Rev. pmid:15109769
Riché EL et al. Novel long-circulating liposomes containing peptide library-lipid conjugates: synthesis and in vivo behavior. 2004 J Drug Target pmid:15545085
Fattal E et al. "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes. 2004 Adv. Drug Deliv. Rev. pmid:15066753
Ho SY et al. Lipid metabolism in zebrafish. 2004 Methods Cell Biol. pmid:15602873
Li SY et al. [Cell membrane phospholipid variation and protein kinase C expression effects on hepatic metastasis of large intestinal carcinoma]. 2004 Zhonghua Wai Ke Za Zhi pmid:15009987
Montes LR et al. Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes. 2004 Biochemistry pmid:15035639
Wang C et al. Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. 2004 Se Pu pmid:15709398
Edwards IJ et al. Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. 2004 Clin. Cancer Res. pmid:15623603
Elmes M et al. The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. 2004 Biochim. Biophys. Acta pmid:15522830