MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Schaur RJ | Basic aspects of the biochemical reactivity of 4-hydroxynonenal. | 2003 Aug-Oct | Mol. Aspects Med. | pmid:12892992 |
Boumann HA et al. | The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro. | 2004 | J. Biol. Chem. | pmid:15258140 |
Laurinavicius S et al. | The origin of phospholipids of the enveloped bacteriophage phi6. | 2004 | Virology | pmid:15262506 |
Sugi T et al. | Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss. | 2004 | J. Obstet. Gynaecol. Res. | pmid:15238112 |
Demana PH et al. | Incorporation of ovalbumin into ISCOMs and related colloidal particles prepared by the lipid film hydration method. | 2004 | Int J Pharm | pmid:15196631 |
Papo N and Shai Y | Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides. | 2004 | Biochemistry | pmid:15157073 |
Demana PH et al. | A comparison of pseudo-ternary diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by lipid-film hydration and dialysis. | 2004 | J. Pharm. Pharmacol. | pmid:15142333 |
Zhang WN et al. | Separation of phosphatidylcholine and phosphatidylethanolamine by using high-performance displacement chromatography. | 2004 | J Chromatogr A | pmid:15146915 |
Tasseva G et al. | Regulation of phosphatidylcholine biosynthesis under salt stress involves choline kinases in Arabidopsis thaliana. | 2004 | FEBS Lett. | pmid:15147879 |
Sprott GD et al. | Liposome adjuvants prepared from the total polar lipids of Haloferax volcanii, Planococcus spp. and Bacillus firmus differ in ability to elicit and sustain immune responses. | 2004 | Vaccine | pmid:15149772 |
Yang YW et al. | The apoptotic and necrotic effects of tomatine adjuvant. | 2004 | Vaccine | pmid:15149791 |
Lukyanov AN and Torchilin VP | Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. | 2004 | Adv. Drug Deliv. Rev. | pmid:15109769 |
Riché EL et al. | Novel long-circulating liposomes containing peptide library-lipid conjugates: synthesis and in vivo behavior. | 2004 | J Drug Target | pmid:15545085 |
Fattal E et al. | "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes. | 2004 | Adv. Drug Deliv. Rev. | pmid:15066753 |
Ho SY et al. | Lipid metabolism in zebrafish. | 2004 | Methods Cell Biol. | pmid:15602873 |
Li SY et al. | [Cell membrane phospholipid variation and protein kinase C expression effects on hepatic metastasis of large intestinal carcinoma]. | 2004 | Zhonghua Wai Ke Za Zhi | pmid:15009987 |
Montes LR et al. | Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes. | 2004 | Biochemistry | pmid:15035639 |
Wang C et al. | Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. | 2004 | Se Pu | pmid:15709398 |
Edwards IJ et al. | Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. | 2004 | Clin. Cancer Res. | pmid:15623603 |
Elmes M et al. | The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. | 2004 | Biochim. Biophys. Acta | pmid:15522830 |