MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kim A et al. | Modulation of the specific interaction of cardiolipin with Cytochrome c by Zwitterionic phospholipids in binary mixed bilayers: a 2H and 31P-NMR study. | 2005 | J. Biochem. Mol. Biol. | pmid:16353315 |
Kuliszkiewicz-Janus M et al. | 31P MRS analysis of the phospholipid composition of normal human peripheral blood mononuclear cells (PBMC). | 2005 | Cell. Mol. Biol. Lett. | pmid:16217549 |
Sato Y et al. | Transformation of Escherichia coli mediated by natural phospholipids. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15665495 |
Zhang W et al. | Phospholipids as determinants of membrane protein topology. Phosphatidylethanolamine is required for the proper topological organization of the gamma-aminobutyric acid permease (GabP) of Escherichia coli. | 2005 | J. Biol. Chem. | pmid:15890647 |
Willumeit R et al. | Structural rearrangement of model membranes by the peptide antibiotic NK-2. | 2005 | Biochim. Biophys. Acta | pmid:15893515 |
Bogdanov M et al. | Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesis. | 2005 | Methods | pmid:15894490 |
Koutoku T et al. | Central administration of phosphatidylserine attenuates isolation stress-induced behavior in chicks. | 2005 | Neurochem. Int. | pmid:15916832 |
López-Revuelta A et al. | Increase in vulnerability to oxidative damage in cholesterol-modified erythrocytes exposed to t-BuOOH. | 2005 | Biochim. Biophys. Acta | pmid:15866485 |
Fishkin NE et al. | Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15870200 |
Danevcic T et al. | Effects of lipid composition on the membrane activity and lipid phase behaviour of Vibrio sp. DSM14379 cells grown at various NaCl concentrations. | 2005 | Biochim. Biophys. Acta | pmid:15878424 |
Kouno T et al. | Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. | 2005 | J. Biol. Chem. | pmid:15857831 |
Opekarová M et al. | Differential effect of phosphatidylethanolamine depletion on raft proteins: further evidence for diversity of rafts in Saccharomyces cerevisiae. | 2005 | Biochim. Biophys. Acta | pmid:15904666 |
Vance JE and Steenbergen R | Metabolism and functions of phosphatidylserine. | 2005 | Prog. Lipid Res. | pmid:15979148 |
Park EJ et al. | Dietary ganglioside and long-chain polyunsaturated fatty acids increase ganglioside GD3 content and alter the phospholipid profile in neonatal rat retina. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:15980250 |
Sennato S et al. | Evidence of domain formation in cardiolipin-glycerophospholipid mixed monolayers. A thermodynamic and AFM study. | 2005 | J Phys Chem B | pmid:16853024 |
Singh AT et al. | Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. | 2005 | Lipids | pmid:16459925 |
Andrä J et al. | Investigation into the interaction of the phosphoporin PhoE with outer membrane lipids: physicochemical characterization and biological activity. | 2005 | Med Chem | pmid:16787338 |
Alves ID et al. | Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy. | 2005 | Biophys. J. | pmid:15501933 |
Emoto K et al. | Local change in phospholipid composition at the cleavage furrow is essential for completion of cytokinesis. | 2005 | J. Biol. Chem. | pmid:16162509 |
Nakagawa K et al. | Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes. | 2005 | J. Lipid Res. | pmid:16150834 |