PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

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Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Kim A et al. Modulation of the specific interaction of cardiolipin with Cytochrome c by Zwitterionic phospholipids in binary mixed bilayers: a 2H and 31P-NMR study. 2005 J. Biochem. Mol. Biol. pmid:16353315
Kuliszkiewicz-Janus M et al. 31P MRS analysis of the phospholipid composition of normal human peripheral blood mononuclear cells (PBMC). 2005 Cell. Mol. Biol. Lett. pmid:16217549
Sato Y et al. Transformation of Escherichia coli mediated by natural phospholipids. 2005 Biosci. Biotechnol. Biochem. pmid:15665495
Zhang W et al. Phospholipids as determinants of membrane protein topology. Phosphatidylethanolamine is required for the proper topological organization of the gamma-aminobutyric acid permease (GabP) of Escherichia coli. 2005 J. Biol. Chem. pmid:15890647
Willumeit R et al. Structural rearrangement of model membranes by the peptide antibiotic NK-2. 2005 Biochim. Biophys. Acta pmid:15893515
Bogdanov M et al. Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesis. 2005 Methods pmid:15894490
Koutoku T et al. Central administration of phosphatidylserine attenuates isolation stress-induced behavior in chicks. 2005 Neurochem. Int. pmid:15916832
López-Revuelta A et al. Increase in vulnerability to oxidative damage in cholesterol-modified erythrocytes exposed to t-BuOOH. 2005 Biochim. Biophys. Acta pmid:15866485
Fishkin NE et al. Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15870200
Danevcic T et al. Effects of lipid composition on the membrane activity and lipid phase behaviour of Vibrio sp. DSM14379 cells grown at various NaCl concentrations. 2005 Biochim. Biophys. Acta pmid:15878424
Kouno T et al. Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. 2005 J. Biol. Chem. pmid:15857831
Opekarová M et al. Differential effect of phosphatidylethanolamine depletion on raft proteins: further evidence for diversity of rafts in Saccharomyces cerevisiae. 2005 Biochim. Biophys. Acta pmid:15904666
Vance JE and Steenbergen R Metabolism and functions of phosphatidylserine. 2005 Prog. Lipid Res. pmid:15979148
Park EJ et al. Dietary ganglioside and long-chain polyunsaturated fatty acids increase ganglioside GD3 content and alter the phospholipid profile in neonatal rat retina. 2005 Invest. Ophthalmol. Vis. Sci. pmid:15980250
Sennato S et al. Evidence of domain formation in cardiolipin-glycerophospholipid mixed monolayers. A thermodynamic and AFM study. 2005 J Phys Chem B pmid:16853024
Singh AT et al. Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. 2005 Lipids pmid:16459925
Andrä J et al. Investigation into the interaction of the phosphoporin PhoE with outer membrane lipids: physicochemical characterization and biological activity. 2005 Med Chem pmid:16787338
Alves ID et al. Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy. 2005 Biophys. J. pmid:15501933
Emoto K et al. Local change in phospholipid composition at the cleavage furrow is essential for completion of cytokinesis. 2005 J. Biol. Chem. pmid:16162509
Nakagawa K et al. Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes. 2005 J. Lipid Res. pmid:16150834