MeSH term | MeSH ID | Detail |
---|---|---|
Iron Overload | D019190 | 11 associated lipids |
Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Blois A et al. | Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. | 2006 | Regul. Pept. | pmid:16445995 |
Dolegowska B et al. | Effect of hemodialysis on the content of fatty acids in monolayers of erythrocyte membranes in patients with chronic renal failure. | 2007 | Ren Fail | pmid:17497467 |
Cesari AB et al. | Changes in the lipid composition of Bradyrhizobium cell envelope reveal a rapid response to water deficit involving lysophosphatidylethanolamine synthesis from phosphatidylethanolamine in outer membrane. | Res. Microbiol. | pmid:29864488 | |
Nayfe R et al. | Seronegative antiphospholipid syndrome. | 2013 | Rheumatology (Oxford) | pmid:23502076 |
Bălănescu P et al. | Association of anti phosphatidyl ethanolamine antibodies and low complement levels in systemic sclerosis patients--results of a cross-sectional study. | 2015 | Scand. J. Clin. Lab. Invest. | pmid:26067612 |
Admasu TD et al. | Lipid profiling of C. elegans strains administered pro-longevity drugs and drug combinations. | 2018 | Sci Data | pmid:30351306 |
Shahine A et al. | A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. | 2017 | Sci Immunol | pmid:29054999 |
Begum H et al. | Discovering and validating between-subject variations in plasma lipids in healthy subjects. | 2016 | Sci Rep | pmid:26743939 |
Farine L et al. | Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei. | 2015 | Sci Rep | pmid:26577437 |
Montaner A et al. | Specific Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cells. | 2018 | Sci Rep | pmid:29323239 |
Kim JS et al. | The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin. | 2017 | Sci Rep | pmid:28740220 |
Dória ML et al. | Epithelial ovarian carcinoma diagnosis by desorption electrospray ionization mass spectrometry imaging. | 2016 | Sci Rep | pmid:27976698 |
Serrán-Aguilera L et al. | Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death. | 2016 | Sci Rep | pmid:27616047 |
Shin H et al. | Genome-wide transcriptome analysis revealed organelle specific responses to temperature variations in algae. | 2016 | Sci Rep | pmid:27883062 |
Dashti M et al. | A phospholipidomic analysis of all defined human plasma lipoproteins. | 2011 | Sci Rep | pmid:22355656 |
Kojima R et al. | A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro. | 2016 | Sci Rep | pmid:27469264 |
Dimitrova M et al. | CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition. | 2016 | Sci Rep | pmid:27040328 |
Zhou M et al. | Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding. | 2011 | Science | pmid:22021858 |
Tsuboyama K et al. | The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. | 2016 | Science | pmid:27885029 |
Wang C et al. | Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. | 2004 | Se Pu | pmid:15709398 |