| MeSH term | MeSH ID | Detail |
|---|---|---|
| Toxoplasmosis | D014123 | 9 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Trematode Infections | D014201 | 8 associated lipids |
| Tangier Disease | D013631 | 8 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Choline Deficiency | D002796 | 16 associated lipids |
| Liver Failure, Acute | D017114 | 11 associated lipids |
| Bacteremia | D016470 | 9 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:15131978 | ||||
| pmid: | ||||
| Guo C et al. | Anti-leprosy drug Clofazimine binds to human Raf1 kinase inhibitory protein and enhances ERK phosphorylation. | 2018 | Acta Biochim. Biophys. Sin. (Shanghai) | pmid:30137201 |
| Madeja Z et al. | New cationic polyprenyl derivative proposed as a lipofecting agent. | 2007 | Acta Biochim. Pol. | pmid:18066397 |
| GOBBI F and STEFANINI M | Circulating anti-AHG anticoagulant in a patient with lupus erythematosus disseminatus. Effect of a cephalin complex in vivo. | 1962 | Acta Haematol. | pmid:13899358 |
| GOBBI F and STEFANINI M | Effects of cephalin on the hemostatic defect of the hemophilia syndrome in vitro and in vivo. | 1961 | Acta Haematol. | pmid:13706151 |
| Sherriff JL et al. | Choline, Its Potential Role in Nonalcoholic Fatty Liver Disease, and the Case for Human and Bacterial Genes. | 2016 | Adv Nutr | pmid:26773011 |
| Odabaei G et al. | Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis. | 2004 | Adv. Cancer Res. | pmid:15327891 |
| Lukyanov AN and Torchilin VP | Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. | 2004 | Adv. Drug Deliv. Rev. | pmid:15109769 |
| Fattal E et al. | "Smart" delivery of antisense oligonucleotides by anionic pH-sensitive liposomes. | 2004 | Adv. Drug Deliv. Rev. | pmid:15066753 |
| Simões S et al. | On the formulation of pH-sensitive liposomes with long circulation times. | 2004 | Adv. Drug Deliv. Rev. | pmid:15066754 |
| Sparrow JR et al. | A2E, a pigment of RPE lipofuscin, is generated from the precursor, A2PE by a lysosomal enzyme activity. | 2008 | Adv. Exp. Med. Biol. | pmid:18188969 |
| Azadi S et al. | Class I Phosphoinositide 3-Kinase Exerts a Differential Role on Cell Survival and Cell Trafficking in Retina. | 2016 | Adv. Exp. Med. Biol. | pmid:26427433 |
| Nesic I et al. | Alterations in phosphatidylethanolamine levels affect the generation of Aβ. | 2012 | Aging Cell | pmid:22023223 |
| Angelova P et al. | Testosterone replacement therapy improves erythrocyte membrane lipid composition in hypogonadal men. | 2012 | Aging Male | pmid:22776010 |
| Zivkovic AM et al. | Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease. | 2009 | Alcohol. Clin. Exp. Res. | pmid:19170661 |
| West AA et al. | Choline intake influences phosphatidylcholine DHA enrichment in nonpregnant women but not in pregnant women in the third trimester. | 2013 | Am. J. Clin. Nutr. | pmid:23446897 |
| Tebo AE et al. | Diagnostic performance of phospholipid-specific assays for the evaluation of antiphospholipid syndrome. | 2008 | Am. J. Clin. Pathol. | pmid:18480002 |
| NEEFE JR et al. | Comparison of the thymol, cephalin-cholesterol flocculation and colloidal red tests in acute viral hepatitis. | 1950 | Am. J. Med. | pmid:15413625 |
| FRISCH AW and QUILLIGAN JJ | A modified cephalin cholesterol test (Hanger) in the study of hepatic disease. | 1946 | Am. J. Med. Sci. | pmid:20996956 |
| DIECKMANN WJ and POTTINGER RE | Serial studies of the cephalin flocculation and thymol turbidity tests in pregnant patients. | 1954 | Am. J. Obstet. Gynecol. | pmid:13207248 |
| CHRISTHILF SM et al. | Liver function during pregnancy and the puerperium, as measured by the cephalin-cholesterol flocculation, the thymol turbidity, and the bromsulfalein tests. | 1950 | Am. J. Obstet. Gynecol. | pmid:15410828 |
| Song H et al. | Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16105858 |
| Godin LM et al. | Spatiotemporal dynamics of actin remodeling and endomembrane trafficking in alveolar epithelial type I cell wound healing. | 2011 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21216977 |
| Sato Y et al. | Autoantibodies to Factor XII and Kininogen-Dependent Antiphosphatidylethanolamine Antibodies in Patients with Recurrent Pregnancy Loss Augment Platelet Aggregation. | 2015 | Am. J. Reprod. Immunol. | pmid:26011374 |
| Zhu X et al. | Regulation of eosinophil adhesion by lysophosphatidylcholine via a non-store-operated Ca2+ channel. | 2007 | Am. J. Respir. Cell Mol. Biol. | pmid:17218614 |
| Zhao M | Lantibiotics as probes for phosphatidylethanolamine. | 2011 | Amino Acids | pmid:21573677 |
| Shin Y et al. | Clostridium kogasensis sp. nov., a novel member of the genus Clostridium, isolated from soil under a corroded gas pipeline. | 2016 | Anaerobe | pmid:26899448 |
| Zhou L et al. | Determination of phosphatidylethanolamine molecular species in various food matrices by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS2). | 2012 | Anal Bioanal Chem | pmid:22349329 |
| Abd-Elhadi S et al. | Total α-synuclein levels in human blood cells, CSF, and saliva determined by a lipid-ELISA. | 2016 | Anal Bioanal Chem | pmid:27624766 |
| Buré C et al. | A single run LC-MS/MS method for phospholipidomics. | 2013 | Anal Bioanal Chem | pmid:23064709 |
| Fuchs B et al. | Phosphatidylcholines and -ethanolamines can be easily mistaken in phospholipid mixtures: a negative ion MALDI-TOF MS study with 9-aminoacridine as matrix and egg yolk as selected example. | 2009 | Anal Bioanal Chem | pmid:19690837 |
| Niklas J et al. | High-throughput phospholipid quantitation in mammalian cells using matrix-assisted laser desorption ionization-time of flight mass spectrometry with N-trifluoroacetyl-phosphatidylethanolamine as internal standard. | 2011 | Anal. Biochem. | pmid:21910962 |
| Horie M et al. | Fluorometric immunoassay based on pH-sensitive dye-encapsulating liposomes and gramicidin channels. | 2007 | Anal. Biochem. | pmid:17718997 |
| Richter G et al. | Comparison of the positive and negative ion electrospray ionization and matrix-assisted laser desorption ionization-time-of-flight mass spectra of the reaction products of phosphatidylethanolamines and hypochlorous acid. | 2008 | Anal. Biochem. | pmid:18295587 |
| SPITZER HL and BALINT JA | A rapid quantitative separation of phosphatidyl ethanolamine and phosphatidyl serine by column chromatography. | 1963 | Anal. Biochem. | pmid:13990206 |
| McLaren DG et al. | An ultraperformance liquid chromatography method for the normal-phase separation of lipids. | 2011 | Anal. Biochem. | pmid:21402047 |
| Kamimori H et al. | Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. | 2005 | Anal. Biochem. | pmid:15649388 |
| Engel H et al. | External surface area determination of lipid vesicles using trinitrobenzene sulfonate and ultraviolet/visible spectrophotometry. | 2013 | Anal. Biochem. | pmid:23933190 |
| Rojas-Betancourt S et al. | Gas-Phase Chemical Separation of Phosphatidylcholine and Phosphatidylethanolamine Cations via Charge Inversion Ion/Ion Chemistry. | 2015 | Anal. Chem. | pmid:26477819 |
| Pham HT and Julian RR | Mass shifting and radical delivery with crown ether attachment for separation and analysis of phosphatidylethanolamine lipids. | 2014 | Anal. Chem. | pmid:24548103 |
| Lanekoff I et al. | Time of flight mass spectrometry imaging of samples fractured in situ with a spring-loaded trap system. | 2010 | Anal. Chem. | pmid:20593800 |
| Wang X et al. | Profiling and relative quantification of phosphatidylethanolamine based on acetone stable isotope derivatization. | 2016 | Anal. Chim. Acta | pmid:26703264 |
| Chen S et al. | Structural elucidation of molecular species of pacific oyster ether amino phospholipids by normal-phase liquid chromatography/negative-ion electrospray ionization and quadrupole/multiple-stage linear ion-trap mass spectrometry. | 2012 | Anal. Chim. Acta | pmid:22713920 |
| STEINBERG BL | Intravenous procaine; its effect on liver function in man as determined by the cephalin flocculation test. | 1949 | Anesthesiology | pmid:15393676 |
| Wichmann O et al. | A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16323228 |
| Sanmarco M et al. | Antigenic profile, prevalence, and clinical significance of antiphospholipid antibodies in women referred for in vitro fertilization. | 2007 | Ann. N. Y. Acad. Sci. | pmid:17894010 |
| FRIEDMAN HH et al. | ODOR MEASUREMENT POSSIBILITIES VIA ENERGY CHANGES IN CEPHALIN MONOLAYERS. | 1964 | Ann. N. Y. Acad. Sci. | pmid:14220554 |
| Decsi T et al. | Inverse association between trans isomeric and long-chain polyunsaturated fatty acids in pregnant women and their newborns: data from three European countries. | 2011 | Ann. Nutr. Metab. | pmid:22142767 |
| Lohner S et al. | Gender differences in the long-chain polyunsaturated fatty acid status: systematic review of 51 publications. | 2013 | Ann. Nutr. Metab. | pmid:23327902 |