PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Toxoplasmosis D014123 9 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Trematode Infections D014201 8 associated lipids
Tangier Disease D013631 8 associated lipids
Abortion, Habitual D000026 5 associated lipids
Choline Deficiency D002796 16 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Bacteremia D016470 9 associated lipids
Cholestasis, Intrahepatic D002780 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Garcia-Manyes S et al. Effect of ion-binding and chemical phospholipid structure on the nanomechanics of lipid bilayers studied by force spectroscopy. 2005 Biophys. J. pmid:15980180
Park EJ et al. Dietary ganglioside and long-chain polyunsaturated fatty acids increase ganglioside GD3 content and alter the phospholipid profile in neonatal rat retina. 2005 Invest. Ophthalmol. Vis. Sci. pmid:15980250
Kalashnikova LA et al. [Anti-phosphatidylethanolamine antibodies in patients with Sneddon's syndrome]. 2005 Klin Med (Mosk) pmid:15984583
Suits F et al. Molecular dynamics investigation of the structural properties of phosphatidylethanolamine lipid bilayers. 2005 J Chem Phys pmid:16035800
Pitman MC et al. Molecular dynamics investigation of dynamical properties of phosphatidylethanolamine lipid bilayers. 2005 J Chem Phys pmid:16035801
Gohil VM et al. Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae. 2005 J. Biol. Chem. pmid:16036913
Bonner PJ et al. The Dif chemosensory pathway is directly involved in phosphatidylethanolamine sensory transduction in Myxococcus xanthus. 2005 Mol. Microbiol. pmid:16102016
Song H et al. Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism. 2006 Am. J. Physiol. Endocrinol. Metab. pmid:16105858
Hiraoka M et al. Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues. 2005 J. Lipid Res. pmid:16106046
Tsukamoto K et al. Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. 2005 J. Biol. Chem. pmid:16115873