| MeSH term | MeSH ID | Detail |
|---|---|---|
| Toxoplasmosis | D014123 | 9 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Trematode Infections | D014201 | 8 associated lipids |
| Tangier Disease | D013631 | 8 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Choline Deficiency | D002796 | 16 associated lipids |
| Liver Failure, Acute | D017114 | 11 associated lipids |
| Bacteremia | D016470 | 9 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sharma S et al. | A Coarse Grained Model for a Lipid Membrane with Physiological Composition and Leaflet Asymmetry. | 2015 | PLoS ONE | pmid:26659855 |
| Lind TK et al. | Formation and Characterization of Supported Lipid Bilayers Composed of Hydrogenated and Deuterated Escherichia coli Lipids. | 2015 | PLoS ONE | pmid:26658241 |
| Ciesielski F et al. | Receptor-independent interaction of bacterial lipopolysaccharide with lipid and lymphocyte membranes; the role of cholesterol. | 2012 | PLoS ONE | pmid:22685597 |
| Zhang X et al. | Distribution, cleavage and lipidation of Atg8 fusion proteins in Spodoptera litura Sl-HP cells. | 2014 | PLoS ONE | pmid:24788719 |
| Patel N et al. | A novel three serum phospholipid panel differentiates normal individuals from those with prostate cancer. | 2014 | PLoS ONE | pmid:24603597 |
| Lin C et al. | Lipid content and composition of oocytes from five coral species: potential implications for future cryopreservation efforts. | 2013 | PLoS ONE | pmid:23469074 |
| Maniti O et al. | Distinct behaviour of the homeodomain derived cell penetrating peptide penetratin in interaction with different phospholipids. | 2010 | PLoS ONE | pmid:21209890 |
| Dixit AK and Jayabaskaran C | Phospholipid mediated activation of calcium dependent protein kinase 1 (CaCDPK1) from chickpea: a new paradigm of regulation. | 2012 | PLoS ONE | pmid:23284721 |
| Bartelds R et al. | Niosomes, an alternative for liposomal delivery. | 2018 | PLoS ONE | pmid:29649223 |
| Gao W et al. | E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I. | 2013 | PLoS ONE | pmid:24023838 |
| Wallner S et al. | Phosphatidylcholine and phosphatidylethanolamine plasmalogens in lipid loaded human macrophages. | 2018 | PLoS ONE | pmid:30308051 |
| Sabharwal T et al. | Defense related decadienal elicits membrane lipid remodeling in the diatom Phaeodactylum tricornutum. | 2017 | PLoS ONE | pmid:28582415 |
| Giles C et al. | The Effects of Long-Term Saturated Fat Enriched Diets on the Brain Lipidome. | 2016 | PLoS ONE | pmid:27907021 |
| Urano H et al. | Novel Anti-Adhesive CMC-PE Hydrogel Significantly Enhanced Morphological and Physiological Recovery after Surgical Decompression in an Animal Model of Entrapment Neuropathy. | 2016 | PLoS ONE | pmid:27741280 |
| Wang S et al. | Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease. | 2016 | PLoS ONE | pmid:27736935 |
| Yabas M et al. | ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes. | 2016 | PLoS ONE | pmid:26799398 |
| Wolny M et al. | Key amino acid residues of ankyrin-sensitive phosphatidylethanolamine/phosphatidylcholine-lipid binding site of βI-spectrin. | 2011 | PLoS ONE | pmid:21738695 |
| Raghava S et al. | The SV40 late protein VP4 is a viroporin that forms pores to disrupt membranes for viral release. | 2011 | PLoS Pathog. | pmid:21738474 |
| Kolomytseva MP et al. | [Heterogeneity of Rhodococcus opacus 1CP as a response to stress induced by chlorophenols]. | 2005 Sep-Oct | Prikl. Biokhim. Mikrobiol. | pmid:16240653 |
| Supattapone S | Phosphatidylethanolamine as a prion cofactor: potential implications for disease pathogenesis. | 2012 Nov-Dec | Prion | pmid:22895101 |