PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Toxoplasmosis D014123 9 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Fatty Liver, Alcoholic D005235 11 associated lipids
Trematode Infections D014201 8 associated lipids
Tangier Disease D013631 8 associated lipids
Abortion, Habitual D000026 5 associated lipids
Choline Deficiency D002796 16 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Bacteremia D016470 9 associated lipids
Cholestasis, Intrahepatic D002780 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Papo N and Shai Y Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides. 2004 Biochemistry pmid:15157073
Kol MA et al. Uptake and remodeling of exogenous phosphatidylethanolamine in E. coli. 2004 Biochim. Biophys. Acta pmid:15164768
Brown AJ Of cholesterol-free mice and men. 2004 Curr. Opin. Lipidol. pmid:15166797
Demana PH et al. Incorporation of ovalbumin into ISCOMs and related colloidal particles prepared by the lipid film hydration method. 2004 Int J Pharm pmid:15196631
Trajkovic-Bodennec S et al. Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes. 2004 Jul-Aug Blood Cells Mol. Dis. pmid:15223015
Sugi T et al. Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss. 2004 J. Obstet. Gynaecol. Res. pmid:15238112
Boumann HA et al. The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro. 2004 J. Biol. Chem. pmid:15258140
Laurinavicius S et al. The origin of phospholipids of the enveloped bacteriophage phi6. 2004 Virology pmid:15262506
Wang X et al. A novel human phosphatidylethanolamine-binding protein resists tumor necrosis factor alpha-induced apoptosis by inhibiting mitogen-activated protein kinase pathway activation and phosphatidylethanolamine externalization. 2004 J. Biol. Chem. pmid:15302887
Doerrler WT et al. MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli. 2004 J. Biol. Chem. pmid:15304478