PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Mammary Neoplasms, Animal D015674 27 associated lipids
Bacteremia D016470 9 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Myocardial Ischemia D017202 11 associated lipids
Sneddon Syndrome D018860 1 associated lipids
Chondrodysplasia Punctata, Rhizomelic D018902 4 associated lipids
Iron Overload D019190 11 associated lipids
Activated Protein C Resistance D020016 1 associated lipids
Hyperhomocysteinemia D020138 6 associated lipids
Venous Thrombosis D020246 11 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Maeda A et al. Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. 2005 J. Biol. Chem. pmid:15755727
Morita YS et al. Compartmentalization of lipid biosynthesis in mycobacteria. 2005 J. Biol. Chem. pmid:15805104
Zhang N et al. [Enhancing effect of Ulex europaeus agglutinin I modified liposomes on oral insulin absorption in mice]. 2004 Yao Xue Xue Bao pmid:15813031
Pan XQ and Lee RJ In vivo antitumor activity of folate receptor-targeted liposomal daunorubicin in a murine leukemia model. 2005 Jan-Feb Anticancer Res. pmid:15816557
Krafft C et al. Near infrared Raman spectra of human brain lipids. 2005 Spectrochim Acta A Mol Biomol Spectrosc pmid:15820887
Kouno T et al. Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. 2005 J. Biol. Chem. pmid:15857831
López-Revuelta A et al. Increase in vulnerability to oxidative damage in cholesterol-modified erythrocytes exposed to t-BuOOH. 2005 Biochim. Biophys. Acta pmid:15866485
Fishkin NE et al. Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate. 2005 Proc. Natl. Acad. Sci. U.S.A. pmid:15870200
Danevcic T et al. Effects of lipid composition on the membrane activity and lipid phase behaviour of Vibrio sp. DSM14379 cells grown at various NaCl concentrations. 2005 Biochim. Biophys. Acta pmid:15878424
Zhang W et al. Phospholipids as determinants of membrane protein topology. Phosphatidylethanolamine is required for the proper topological organization of the gamma-aminobutyric acid permease (GabP) of Escherichia coli. 2005 J. Biol. Chem. pmid:15890647