PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Mammary Neoplasms, Animal D015674 27 associated lipids
Bacteremia D016470 9 associated lipids
Liver Failure, Acute D017114 11 associated lipids
Myocardial Ischemia D017202 11 associated lipids
Sneddon Syndrome D018860 1 associated lipids
Chondrodysplasia Punctata, Rhizomelic D018902 4 associated lipids
Iron Overload D019190 11 associated lipids
Activated Protein C Resistance D020016 1 associated lipids
Hyperhomocysteinemia D020138 6 associated lipids
Venous Thrombosis D020246 11 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Chen YG et al. Bacillus zhanjiangensis sp. nov., isolated from an oyster in South China Sea. 2011 Antonie Van Leeuwenhoek pmid:20865333
Zhou YX et al. Bacillus mesophilus sp. nov., an alginate-degrading bacterium isolated from a soil sample collected from an abandoned marine solar saltern. 2016 Antonie Van Leeuwenhoek pmid:27084709
Choi J et al. Thalassorhabdus aurantiaca gen. nov., sp. nov., a new member of the family Flavobacteriaceae isolated from seawater in South Korea. 2018 Antonie Van Leeuwenhoek pmid:29948434
Elvas F et al. Phosphatidylethanolamine targeting for cell death imaging in early treatment response evaluation and disease diagnosis. 2017 Apoptosis pmid:28623512
Lau BY et al. Fat-1 gene modulates the fatty acid composition of femoral and vertebral phospholipids. 2010 Appl Physiol Nutr Metab pmid:20725110
Johnson TJ et al. The infrared spectra of Bacillus bacteria part I: vegetative Bacillus versus sporulated cells and the contributions of phospholipids to vegetative infrared spectra. 2009 Appl Spectrosc pmid:19678986
Kim YA et al. Integration of Quercetin-Iron Complexes into Phosphatidylcholine or Phosphatidylethanolamine Liposomes. 2015 Appl. Biochem. Biotechnol. pmid:26047928
Henderson CM et al. Fermentation temperature modulates phosphatidylethanolamine and phosphatidylinositol levels in the cell membrane of Saccharomyces cerevisiae. 2013 Appl. Environ. Microbiol. pmid:23811519
Moore EK et al. Novel mono-, di-, and trimethylornithine membrane lipids in northern wetland planctomycetes. 2013 Appl. Environ. Microbiol. pmid:23995937
Cerminati S et al. Development of a highly efficient oil degumming process using a novel phosphatidylinositol-specific phospholipase C enzyme. 2017 Appl. Microbiol. Biotechnol. pmid:28238084
Lageix F et al. [Association between the presence of antiphospholipid antibodies and the occurrence of autism spectrum disorder in childhood]. 2015 Arch Pediatr pmid:26386813
Meuillet EJ et al. Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. 2004 Arch. Biochem. Biophys. pmid:15313215
REHBINDER D and GREENBERG DM STUDIES ON THE METHYLATION OF ETHANOLAMINE PHOSPHATIDES BY LIVER PREPARATIONS. 1965 Arch. Biochem. Biophys. pmid:14281933
CRUZ WO et al. Crude cephalin as the active substance of organ extracts able to convert venous blood into hemostatic blood. 1959 Arch. Biochem. Biophys. pmid:13813116
MCCANDLESS EL and ZILVERSMIT DB The effect of cholesterol on the turnover of lecithin, cephalin and sphingomyelin in the rabbit. 1956 Arch. Biochem. Biophys. pmid:13328128
Ansari IH et al. Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion. 2017 Arch. Biochem. Biophys. pmid:28193492
Gai Z et al. Characterization of Atg8 in lepidopteran insect cells. 2013 Arch. Insect Biochem. Physiol. pmid:23959953
Wang G et al. Bacterioplanes sanyensis gen. nov., sp. nov., a PHB-accumulating bacterium isolated from a pool of Spirulina platensis cultivation. 2014 Arch. Microbiol. pmid:25038945
Lee K et al. Paradonghicola geojensis gen. nov., sp. nov., isolated from seawater, Geoje-si, South Korea. 2016 Arch. Microbiol. pmid:26971334
Romanenko LA et al. Winogradskyella profunda sp. nov. isolated from the Chukchi Sea bottom sediments. 2019 Arch. Microbiol. pmid:30187095