MeSH term | MeSH ID | Detail |
---|---|---|
Hemolysis | D006461 | 131 associated lipids |
Adenocarcinoma | D000230 | 166 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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pmid: | ||||
Sehayek E et al. | Localization of the PE methylation pathway and SR-BI to the canalicular membrane: evidence for apical PC biosynthesis that may promote biliary excretion of phospholipid and cholesterol. | 2003 | J. Lipid Res. | pmid:12810817 |
Prades J et al. | Effects of unsaturated fatty acids and triacylglycerols on phosphatidylethanolamine membrane structure. | 2003 | J. Lipid Res. | pmid:12810821 |
Noga AA and Vance DE | Insights into the requirement of phosphatidylcholine synthesis for liver function in mice. | 2003 | J. Lipid Res. | pmid:12837848 |
Schaur RJ | Basic aspects of the biochemical reactivity of 4-hydroxynonenal. | 2003 Aug-Oct | Mol. Aspects Med. | pmid:12892992 |
MILSTONE JH | Bovine serum as a complement for the combined effects of thrombokinase and cephalin. | 1952 | Yale J Biol Med | pmid:13015949 |
BAER E et al. | Migration during hydrolysis of esters of glycerophosphoric acid. III. Cephalin and glycerylphosphorylethanolamine. | 1953 | J. Biol. Chem. | pmid:13034779 |
NORMAN JM and DAWSON RM | A method for measuring the deposition of 32P in phosphatidylethanolamine and its application to rat-brain tissue. | 1953 | Biochem. J. | pmid:13058914 |
AXELROD J et al. | The direct determination of phosphatidyl ethanolamine and phosphatidyl serine in plasma and red blood cells. | 1953 | J. Biol. Chem. | pmid:13117868 |
DIECKMANN WJ and POTTINGER RE | Serial studies of the cephalin flocculation and thymol turbidity tests in pregnant patients. | 1954 | Am. J. Obstet. Gynecol. | pmid:13207248 |
MILSTONE JH | Effect of blood thrombokinase, as influenced by soy bean trypsin inhibitor, ultracentrifugation, and accessory factors. | 1955 | J. Gen. Physiol. | pmid:13242762 |
O'BRIEN JR | The similarity of the action of phosphatidyl-ethanolamine and platelets in blood coagulation. | 1956 | J. Clin. Pathol. | pmid:13306791 |
MCCANDLESS EL and ZILVERSMIT DB | The effect of cholesterol on the turnover of lecithin, cephalin and sphingomyelin in the rabbit. | 1956 | Arch. Biochem. Biophys. | pmid:13328128 |
ROBINSON DS and POOLE JC | The similar effect of chylomicra and ethanolamine phosphatide on the generation of thrombin during coagulation. | 1956 | Q J Exp Physiol Cogn Med Sci | pmid:13485325 |
POOLE JC and ROBINSON DS | Further observations on the effects of ethanolamine phosphatide on plasma coagulation. | 1956 | Q J Exp Physiol Cogn Med Sci | pmid:13485345 |
HAWKE JC | The fatty acids of phosphatidylethanolamine and phosphatidylcholine from hen's egg. | 1959 | Biochem. J. | pmid:13638270 |
LITHERLAND OK and BOGOCH A | A comparison of the cephalin-cholesterol flocculation and thymol turbidity tests in patients with portal cirrhosis. | 1959 | Can Med Assoc J | pmid:13662955 |
GIBSON KD et al. | The enzymatic conversion of phospholipid ethanolamine to phospholipid choline in rat liver. | 1961 | J. Biol. Chem. | pmid:13705126 |
GOBBI F and STEFANINI M | Effects of cephalin on the hemostatic defect of the hemophilia syndrome in vitro and in vivo. | 1961 | Acta Haematol. | pmid:13706151 |
HOKIN LE and HOKIN MR | Studies on the carrier function of phosphatidic acid in sodium transport. I. The turnover of phosphatidic acid and phosphoinositide in the avian salt gland on stimulation of secretion. | 1960 | J. Gen. Physiol. | pmid:13715209 |