MeSH term | MeSH ID | Detail |
---|---|---|
Venous Thromboembolism | D054556 | 2 associated lipids |
Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nishibori A et al. | Phosphatidylethanolamine domains and localization of phospholipid synthases in Bacillus subtilis membranes. | 2005 | J. Bacteriol. | pmid:15743965 |
Krafft C et al. | Near infrared Raman spectra of human brain lipids. | 2005 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:15820887 |
Pacetti D et al. | High performance liquid chromatography-tandem mass spectrometry of phospholipid molecular species in eggs from hens fed diets enriched in seal blubber oil. | 2005 | J Chromatogr A | pmid:16298186 |
Vance JE and Steenbergen R | Metabolism and functions of phosphatidylserine. | 2005 | Prog. Lipid Res. | pmid:15979148 |
Park EJ et al. | Dietary ganglioside and long-chain polyunsaturated fatty acids increase ganglioside GD3 content and alter the phospholipid profile in neonatal rat retina. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:15980250 |
Ahn T et al. | Involvement of nonlamellar-prone lipids in the stability increase of human cytochrome P450 1A2 in reconstituted membranes. | 2005 | Biochemistry | pmid:15966743 |
Novikova NN et al. | X-ray fluorescence methods for investigations of lipid/protein membrane models. | 2005 | J Synchrotron Radiat | pmid:15968131 |
Lee ES et al. | The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells. | 2005 | Neurotoxicology | pmid:15950286 |
Emoto K et al. | Local change in phospholipid composition at the cleavage furrow is essential for completion of cytokinesis. | 2005 | J. Biol. Chem. | pmid:16162509 |
Nakagawa K et al. | Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes. | 2005 | J. Lipid Res. | pmid:16150834 |