PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Venous Thromboembolism D054556 2 associated lipids
Barth Syndrome D056889 3 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Begum H et al. Discovering and validating between-subject variations in plasma lipids in healthy subjects. 2016 Sci Rep pmid:26743939
Montaner A et al. Specific Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cells. 2018 Sci Rep pmid:29323239
Dória ML et al. Epithelial ovarian carcinoma diagnosis by desorption electrospray ionization mass spectrometry imaging. 2016 Sci Rep pmid:27976698
Shin H et al. Genome-wide transcriptome analysis revealed organelle specific responses to temperature variations in algae. 2016 Sci Rep pmid:27883062
Dashti M et al. A phospholipidomic analysis of all defined human plasma lipoproteins. 2011 Sci Rep pmid:22355656
Kojima R et al. A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro. 2016 Sci Rep pmid:27469264
Dimitrova M et al. CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition. 2016 Sci Rep pmid:27040328
Shahine A et al. A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. 2017 Sci Immunol pmid:29054999
Admasu TD et al. Lipid profiling of C. elegans strains administered pro-longevity drugs and drug combinations. 2018 Sci Data pmid:30351306
Bălănescu P et al. Association of anti phosphatidyl ethanolamine antibodies and low complement levels in systemic sclerosis patients--results of a cross-sectional study. 2015 Scand. J. Clin. Lab. Invest. pmid:26067612
Nayfe R et al. Seronegative antiphospholipid syndrome. 2013 Rheumatology (Oxford) pmid:23502076
Cesari AB et al. Changes in the lipid composition of Bradyrhizobium cell envelope reveal a rapid response to water deficit involving lysophosphatidylethanolamine synthesis from phosphatidylethanolamine in outer membrane. Res. Microbiol. pmid:29864488
Dolegowska B et al. Effect of hemodialysis on the content of fatty acids in monolayers of erythrocyte membranes in patients with chronic renal failure. 2007 Ren Fail pmid:17497467
Blois A et al. Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. 2006 Regul. Pept. pmid:16445995
Aldrovandi M et al. DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression. 2017 Redox Biol pmid:28160743
Naik SR et al. Liposomes as potential carrier system for targeted delivery of polyene antibiotics. 2013 Recent Pat Inflamm Allergy Drug Discov pmid:23745986
Moe MK et al. Vicinal hydroxylation of unsaturated fatty acids for structural characterization of intact neutral phospholipids by negative electrospray ionization tandem quadrupole mass spectrometry. 2004 Rapid Commun. Mass Spectrom. pmid:15317043
Svensson E et al. Compound-specific stable isotope analysis of nitrogen-containing intact polar lipids. 2015 Rapid Commun. Mass Spectrom. pmid:26522319
POOLE JC and ROBINSON DS Further observations on the effects of ethanolamine phosphatide on plasma coagulation. 1956 Q J Exp Physiol Cogn Med Sci pmid:13485345
ROBINSON DS and POOLE JC The similar effect of chylomicra and ethanolamine phosphatide on the generation of thrombin during coagulation. 1956 Q J Exp Physiol Cogn Med Sci pmid:13485325