MeSH term | MeSH ID | Detail |
---|---|---|
Venous Thromboembolism | D054556 | 2 associated lipids |
Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Mead FC and Williams AJ | Electrostatic mechanisms underlie neomycin block of the cardiac ryanodine receptor channel (RyR2). | 2004 | Biophys. J. | pmid:15361409 |
Zhang N et al. | [The enhancing effect of tomato lectin modified liposomes of insulin on oral absorption in mice]. | 2004 | Yao Xue Xue Bao | pmid:15338884 |
Meuillet EJ et al. | Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. | 2004 | Arch. Biochem. Biophys. | pmid:15313215 |
Moe MK et al. | Vicinal hydroxylation of unsaturated fatty acids for structural characterization of intact neutral phospholipids by negative electrospray ionization tandem quadrupole mass spectrometry. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15317043 |
Sugai R et al. | Overexpression of gnsA, a multicopy suppressor of the secG null mutation, increases acidic phospholipid contents by inhibiting phosphatidylethanolamine synthesis at low temperatures. | 2004 | J. Bacteriol. | pmid:15317805 |
Wang X et al. | A novel human phosphatidylethanolamine-binding protein resists tumor necrosis factor alpha-induced apoptosis by inhibiting mitogen-activated protein kinase pathway activation and phosphatidylethanolamine externalization. | 2004 | J. Biol. Chem. | pmid:15302887 |
Doerrler WT et al. | MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli. | 2004 | J. Biol. Chem. | pmid:15304478 |
Barker AP et al. | A novel extracellular phospholipase C of Pseudomonas aeruginosa is required for phospholipid chemotaxis. | 2004 | Mol. Microbiol. | pmid:15306013 |
Khopade AJ et al. | Phase structures of a hydrated anionic phospholipid composition containing cationic dendrimers and pegylated lipids. | 2004 | Langmuir | pmid:15323476 |
Odabaei G et al. | Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis. | 2004 | Adv. Cancer Res. | pmid:15327891 |
Iwamoto K et al. | [Relationship between localized phosphatidylethanolamine exposure and yeast cell polarity]. | 2004 | Tanpakushitsu Kakusan Koso | pmid:15346886 |
Riché EL et al. | Novel long-circulating liposomes containing peptide library-lipid conjugates: synthesis and in vivo behavior. | 2004 | J Drug Target | pmid:15545085 |
Otto GP et al. | Dictyostelium macroautophagy mutants vary in the severity of their developmental defects. | 2004 | J. Biol. Chem. | pmid:14736886 |
Choi HS et al. | Regulation of phospholipid synthesis in the yeast cki1Delta eki1Delta mutant defective in the Kennedy pathway. The Cho1-encoded phosphatidylserine synthase is regulated by mRNA stability. | 2004 | J. Biol. Chem. | pmid:14739287 |
Ho SY et al. | Lipid metabolism in zebrafish. | 2004 | Methods Cell Biol. | pmid:15602873 |
Wang C et al. | Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. | 2004 | Se Pu | pmid:15709398 |
Edwards IJ et al. | Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. | 2004 | Clin. Cancer Res. | pmid:15623603 |
Trajkovic-Bodennec S et al. | Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes. | 2004 Jul-Aug | Blood Cells Mol. Dis. | pmid:15223015 |
Vasil'eva OB et al. | [Biochemical properties of the the lipoproteins lipid composition in fishes of the different ecology: trout Salmo irideus L. and whitefish Coregonus lavaretus L]. | 2004 Mar-Apr | Izv. Akad. Nauk. Ser. Biol. | pmid:15131975 |
Malisiova F et al. | Liposomal formulations from phospholipids of Greek almond oil. Properties and biological activity. | 2004 May-Jun | Z. Naturforsch., C, J. Biosci. | pmid:18998396 |
Nishibori A et al. | Phosphatidylethanolamine domains and localization of phospholipid synthases in Bacillus subtilis membranes. | 2005 | J. Bacteriol. | pmid:15743965 |
Krafft C et al. | Near infrared Raman spectra of human brain lipids. | 2005 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:15820887 |
Maeda A et al. | Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo. | 2005 | J. Biol. Chem. | pmid:15755727 |
Morita YS et al. | Compartmentalization of lipid biosynthesis in mycobacteria. | 2005 | J. Biol. Chem. | pmid:15805104 |
Goss R et al. | Role of hexagonal structure-forming lipids in diadinoxanthin and violaxanthin solubilization and de-epoxidation. | 2005 | Biochemistry | pmid:15751979 |
Zhai X et al. | Small angle X-ray scattering (SAXS) and differential scanning calorimetry (DSC) studies of amide phospholipids. | 2005 | Chem. Phys. Lipids | pmid:15589228 |
Nguyen LT et al. | Structural studies and model membrane interactions of two peptides derived from bovine lactoferricin. | 2005 | J. Pept. Sci. | pmid:15635665 |
Kuliszkiewicz-Janus M et al. | 31P MRS analysis of the phospholipid composition of normal human peripheral blood mononuclear cells (PBMC). | 2005 | Cell. Mol. Biol. Lett. | pmid:16217549 |
Pacetti D et al. | High performance liquid chromatography-tandem mass spectrometry of phospholipid molecular species in eggs from hens fed diets enriched in seal blubber oil. | 2005 | J Chromatogr A | pmid:16298186 |
Müller H et al. | A diet rich in phosphatidylethanolamine increases plasma homocysteine in mink: a comparison with a soybean oil diet. | 2005 | Br. J. Nutr. | pmid:16277769 |
Tsukamoto K et al. | Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. | 2005 | J. Biol. Chem. | pmid:16115873 |
Suits F et al. | Molecular dynamics investigation of the structural properties of phosphatidylethanolamine lipid bilayers. | 2005 | J Chem Phys | pmid:16035800 |
Bogdanov M et al. | Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesis. | 2005 | Methods | pmid:15894490 |
Koutoku T et al. | Central administration of phosphatidylserine attenuates isolation stress-induced behavior in chicks. | 2005 | Neurochem. Int. | pmid:15916832 |
López-Revuelta A et al. | Increase in vulnerability to oxidative damage in cholesterol-modified erythrocytes exposed to t-BuOOH. | 2005 | Biochim. Biophys. Acta | pmid:15866485 |
Fishkin NE et al. | Isolation and characterization of a retinal pigment epithelial cell fluorophore: an all-trans-retinal dimer conjugate. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15870200 |
Danevcic T et al. | Effects of lipid composition on the membrane activity and lipid phase behaviour of Vibrio sp. DSM14379 cells grown at various NaCl concentrations. | 2005 | Biochim. Biophys. Acta | pmid:15878424 |
Kouno T et al. | Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains. | 2005 | J. Biol. Chem. | pmid:15857831 |
Opekarová M et al. | Differential effect of phosphatidylethanolamine depletion on raft proteins: further evidence for diversity of rafts in Saccharomyces cerevisiae. | 2005 | Biochim. Biophys. Acta | pmid:15904666 |
Vance JE and Steenbergen R | Metabolism and functions of phosphatidylserine. | 2005 | Prog. Lipid Res. | pmid:15979148 |
Park EJ et al. | Dietary ganglioside and long-chain polyunsaturated fatty acids increase ganglioside GD3 content and alter the phospholipid profile in neonatal rat retina. | 2005 | Invest. Ophthalmol. Vis. Sci. | pmid:15980250 |
Ahn T et al. | Involvement of nonlamellar-prone lipids in the stability increase of human cytochrome P450 1A2 in reconstituted membranes. | 2005 | Biochemistry | pmid:15966743 |
Novikova NN et al. | X-ray fluorescence methods for investigations of lipid/protein membrane models. | 2005 | J Synchrotron Radiat | pmid:15968131 |
Lee ES et al. | The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells. | 2005 | Neurotoxicology | pmid:15950286 |
Jacobs RL et al. | Physiological regulation of phospholipid methylation alters plasma homocysteine in mice. | 2005 | J. Biol. Chem. | pmid:15958390 |
Kalashnikova LA et al. | [Anti-phosphatidylethanolamine antibodies in patients with Sneddon's syndrome]. | 2005 | Klin Med (Mosk) | pmid:15984583 |
Singh AT et al. | Parathyroid hormone stimulates phosphatidylethanolamine hydrolysis by phospholipase D in osteoblastic cells. | 2005 | Lipids | pmid:16459925 |
Alves ID et al. | Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy. | 2005 | Biophys. J. | pmid:15501933 |
Emoto K et al. | Local change in phospholipid composition at the cleavage furrow is essential for completion of cytokinesis. | 2005 | J. Biol. Chem. | pmid:16162509 |
Nakagawa K et al. | Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes. | 2005 | J. Lipid Res. | pmid:16150834 |