| MeSH term | MeSH ID | Detail |
|---|---|---|
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kamimori H et al. | Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. | 2005 | Anal. Biochem. | pmid:15649388 |
| Murzyn K et al. | Phosphatidylethanolamine-phosphatidylglycerol bilayer as a model of the inner bacterial membrane. | 2005 | Biophys. J. | pmid:15556990 |
| Manucha W et al. | Effect of losartan pretreatment on kidney lipid content after unilateral obstruction in rats. | 2005 | Cell. Mol. Biol. (Noisy-le-grand) | pmid:16309578 |
| Zhirnov AE et al. | Lipid composition determines interaction of liposome membranes with Pluronic L61. | 2005 | Biochim. Biophys. Acta | pmid:16405999 |
| Kim A et al. | Modulation of the specific interaction of cardiolipin with Cytochrome c by Zwitterionic phospholipids in binary mixed bilayers: a 2H and 31P-NMR study. | 2005 | J. Biochem. Mol. Biol. | pmid:16353315 |
| Pitman MC et al. | Molecular dynamics investigation of dynamical properties of phosphatidylethanolamine lipid bilayers. | 2005 | J Chem Phys | pmid:16035801 |
| Gohil VM et al. | Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae. | 2005 | J. Biol. Chem. | pmid:16036913 |
| Bonner PJ et al. | The Dif chemosensory pathway is directly involved in phosphatidylethanolamine sensory transduction in Myxococcus xanthus. | 2005 | Mol. Microbiol. | pmid:16102016 |
| Hiraoka M et al. | Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues. | 2005 | J. Lipid Res. | pmid:16106046 |
| Sabah J et al. | Role of albumin as a fatty acid carrier for biosynthesis of lens lipids. | 2005 | Exp. Eye Res. | pmid:15652523 |
| Musiol HJ et al. | Toward semisynthetic lipoproteins by convergent strategies based on click and ligation chemistry. | 2005 | Chembiochem | pmid:15723440 |
| Sato Y et al. | Transformation of Escherichia coli mediated by natural phospholipids. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15665495 |
| Zhang W et al. | Phospholipids as determinants of membrane protein topology. Phosphatidylethanolamine is required for the proper topological organization of the gamma-aminobutyric acid permease (GabP) of Escherichia coli. | 2005 | J. Biol. Chem. | pmid:15890647 |
| Willumeit R et al. | Structural rearrangement of model membranes by the peptide antibiotic NK-2. | 2005 | Biochim. Biophys. Acta | pmid:15893515 |
| Sennato S et al. | Evidence of domain formation in cardiolipin-glycerophospholipid mixed monolayers. A thermodynamic and AFM study. | 2005 | J Phys Chem B | pmid:16853024 |
| Bowen RA and Clandinin MT | Maternal dietary 22 : 6n-3 is more effective than 18 : 3n-3 in increasing the 22 : 6n-3 content in phospholipids of glial cells from neonatal rat brain. | 2005 | Br. J. Nutr. | pmid:15975158 |
| Andrä J et al. | Investigation into the interaction of the phosphoporin PhoE with outer membrane lipids: physicochemical characterization and biological activity. | 2005 | Med Chem | pmid:16787338 |
| Garcia-Manyes S et al. | Effect of ion-binding and chemical phospholipid structure on the nanomechanics of lipid bilayers studied by force spectroscopy. | 2005 | Biophys. J. | pmid:15980180 |
| Jernigan Jr HM et al. | Effects of cataractogenesis on the CDP-choline pathway: increased phospholipid synthesis in lenses from galactosemic rats and 13/N guinea pigs. | 2005 Jan-Feb | Ophthalmic Res. | pmid:15604593 |
| Pan XQ and Lee RJ | In vivo antitumor activity of folate receptor-targeted liposomal daunorubicin in a murine leukemia model. | 2005 Jan-Feb | Anticancer Res. | pmid:15816557 |
| Funari SS et al. | Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes. | 2005 Jul-Aug | Mol. Membr. Biol. | pmid:16154902 |
| Hocquellet A et al. | Evidence for a different metabolism of PC and PE in shoots and roots. | 2005 Oct-Nov | Plant Physiol. Biochem. | pmid:16325411 |
| Kolomytseva MP et al. | [Heterogeneity of Rhodococcus opacus 1CP as a response to stress induced by chlorophenols]. | 2005 Sep-Oct | Prikl. Biokhim. Mikrobiol. | pmid:16240653 |
| Carmieli R et al. | Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes. | 2006 | Biophys. J. | pmid:16258052 |
| Hamai C et al. | Effect of average phospholipid curvature on supported bilayer formation on glass by vesicle fusion. | 2006 | Biophys. J. | pmid:16299084 |
| Sou YS et al. | Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16. | 2006 | J. Biol. Chem. | pmid:16303767 |
| Lins L et al. | "De novo" design of peptides with specific lipid-binding properties. | 2006 | Biophys. J. | pmid:16275638 |
| Jin JK et al. | Phospholipase D1 is up-regulated in the mitochondrial fraction from the brains of Alzheimer's disease patients. | 2006 | Neurosci. Lett. | pmid:16973278 |
| Hicks AM et al. | Unique molecular signatures of glycerophospholipid species in different rat tissues analyzed by tandem mass spectrometry. | 2006 | Biochim. Biophys. Acta | pmid:16860597 |
| Xu Y et al. | A Drosophila model of Barth syndrome. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16855048 |
| Takahashi K et al. | Purification and ATPase activity of human ABCA1. | 2006 | J. Biol. Chem. | pmid:16500904 |
| Petelska AD et al. | The interfacial tension of the lipid membrane formed from lipid-cholesterol and lipid-lipid systems. | 2006 | Cell Biochem. Biophys. | pmid:16456222 |
| Clark MC et al. | NMR assignment of rat Raf kinase inhibitor protein. | 2006 | J. Biomol. NMR | pmid:16456706 |
| Oberfeld B et al. | Phospholipids occupy the internal lumen of the c ring of the ATP synthase of Escherichia coli. | 2006 | Biochemistry | pmid:16460030 |
| Wachtel E et al. | A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes. | 2006 | Biochemistry | pmid:16430232 |
| Shizuka M et al. | Synthesis of isoprostanyl phosphatidylcholine and isoprostanyl phosphatidylethanolamine. | 2006 | J. Org. Chem. | pmid:16468779 |
| Higuchi O et al. | Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor. | 2006 | J. Lipid Res. | pmid:16470027 |
| Blois A et al. | Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. | 2006 | Regul. Pept. | pmid:16445995 |
| Alder-Baerens N et al. | Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. | 2006 | Mol. Biol. Cell | pmid:16452632 |
| Min Y et al. | A distinctive fatty acid profile in circulating lipids of Korean gestational diabetics: a pilot study. | 2006 | Diabetes Res. Clin. Pract. | pmid:16455150 |
| Tosch W et al. | Molecular species of phosphatidylethanolamine from continuous cultures of Saccharomyces pastorianus syn. carlsbergensis strains. | 2006 | Yeast | pmid:16491465 |
| Arnt L et al. | Membrane activity of biomimetic facially amphiphilic antibiotics. | 2006 | J Phys Chem B | pmid:16494408 |
| Ishida BY et al. | High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture. | 2006 | Br J Ophthalmol | pmid:16622093 |
| Hincha DK | High concentrations of the compatible solute glycinebetaine destabilize model membranes under stress conditions. | 2006 | Cryobiology | pmid:16696965 |
| Xie J et al. | Phosphatidylethanolamine and monoglucosyldiacylglycerol are interchangeable in supporting topogenesis and function of the polytopic membrane protein lactose permease. | 2006 | J. Biol. Chem. | pmid:16698795 |
| Separovic D et al. | Ceramide response post-photodamage is absent after treatment with HA14-1. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16701558 |
| Russano AM et al. | Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. | 2006 | J. Allergy Clin. Immunol. | pmid:16675349 |
| Li Z et al. | The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. | 2006 | Cell Metab. | pmid:16679290 |
| Sternin E et al. | Changes in molecular order across the lamellar-to-inverted hexagonal phase transition depend on the position of the double-bond in mono-unsaturated phospholipid dispersions. | 2006 | Chem. Phys. Lipids | pmid:16574088 |
| Buzón V and Cladera J | Effect of cholesterol on the interaction of the HIV GP41 fusion peptide with model membranes. Importance of the membrane dipole potential. | 2006 | Biochemistry | pmid:17176099 |