MeSH term | MeSH ID | Detail |
---|---|---|
Venous Thromboembolism | D054556 | 2 associated lipids |
Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Barker AP et al. | A novel extracellular phospholipase C of Pseudomonas aeruginosa is required for phospholipid chemotaxis. | 2004 | Mol. Microbiol. | pmid:15306013 |
Meuillet EJ et al. | Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. | 2004 | Arch. Biochem. Biophys. | pmid:15313215 |
Moe MK et al. | Vicinal hydroxylation of unsaturated fatty acids for structural characterization of intact neutral phospholipids by negative electrospray ionization tandem quadrupole mass spectrometry. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15317043 |
Sugai R et al. | Overexpression of gnsA, a multicopy suppressor of the secG null mutation, increases acidic phospholipid contents by inhibiting phosphatidylethanolamine synthesis at low temperatures. | 2004 | J. Bacteriol. | pmid:15317805 |
Khopade AJ et al. | Phase structures of a hydrated anionic phospholipid composition containing cationic dendrimers and pegylated lipids. | 2004 | Langmuir | pmid:15323476 |
Odabaei G et al. | Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis. | 2004 | Adv. Cancer Res. | pmid:15327891 |
Zhang N et al. | [The enhancing effect of tomato lectin modified liposomes of insulin on oral absorption in mice]. | 2004 | Yao Xue Xue Bao | pmid:15338884 |
Kihara A and Igarashi Y | Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry. | 2004 | Mol. Biol. Cell | pmid:15342785 |
Polozov IV and Gawrisch K | Domains in binary SOPC/POPE lipid mixtures studied by pulsed field gradient 1H MAS NMR. | 2004 | Biophys. J. | pmid:15345553 |
Shaikh SR et al. | Oleic and docosahexaenoic acid differentially phase separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study. | 2004 | Biophys. J. | pmid:15345554 |
Iwamoto K et al. | [Relationship between localized phosphatidylethanolamine exposure and yeast cell polarity]. | 2004 | Tanpakushitsu Kakusan Koso | pmid:15346886 |
Mead FC and Williams AJ | Electrostatic mechanisms underlie neomycin block of the cardiac ryanodine receptor channel (RyR2). | 2004 | Biophys. J. | pmid:15361409 |
Berson EL et al. | Further evaluation of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment: subgroup analyses. | 2004 | Arch. Ophthalmol. | pmid:15364709 |
Schleheck D et al. | Parvibaculum lavamentivorans gen. nov., sp. nov., a novel heterotroph that initiates catabolism of linear alkylbenzenesulfonate. | 2004 | Int. J. Syst. Evol. Microbiol. | pmid:15388700 |
STEINBERG BL | Intravenous procaine; its effect on liver function in man as determined by the cephalin flocculation test. | 1949 | Anesthesiology | pmid:15393676 |
CHRISTHILF SM et al. | Liver function during pregnancy and the puerperium, as measured by the cephalin-cholesterol flocculation, the thymol turbidity, and the bromsulfalein tests. | 1950 | Am. J. Obstet. Gynecol. | pmid:15410828 |
NEEFE JR et al. | Comparison of the thymol, cephalin-cholesterol flocculation and colloidal red tests in acute viral hepatitis. | 1950 | Am. J. Med. | pmid:15413625 |
Liu F et al. | Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers. | 2004 | Biophys. J. | pmid:15454444 |
Lairion F and Disalvo EA | Effect of phloretin on the dipole potential of phosphatidylcholine, phosphatidylethanolamine, and phosphatidylglycerol monolayers. | 2004 | Langmuir | pmid:15461500 |
Iwamoto K et al. | Local exposure of phosphatidylethanolamine on the yeast plasma membrane is implicated in cell polarity. | 2004 | Genes Cells | pmid:15461661 |