| MeSH term | MeSH ID | Detail |
|---|---|---|
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Merino-Montero S et al. | Effects of lactose permease of Escherichia coli on the anisotropy and electrostatic surface potential of liposomes. | 2006 | Biophys. Chem. | pmid:16242835 |
| Kaliszewski P et al. | Enhanced levels of Pis1p (phosphatidylinositol synthase) improve the growth of Saccharomyces cerevisiae cells deficient in Rsp5 ubiquitin ligase. | 2006 | Biochem. J. | pmid:16363994 |
| Wichmann O et al. | A small-molecule FRET probe to monitor phospholipase A2 activity in cells and organisms. | 2006 | Angew. Chem. Int. Ed. Engl. | pmid:16323228 |
| Boumann HA et al. | Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote. | 2006 | Mol. Biol. Cell | pmid:16339082 |
| Sharpley MS et al. | Interactions between phospholipids and NADH:ubiquinone oxidoreductase (complex I) from bovine mitochondria. | 2006 | Biochemistry | pmid:16388600 |
| Carmieli R et al. | Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes. | 2006 | Biophys. J. | pmid:16258052 |
| Song H et al. | Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16105858 |
| Bonner PJ and Shimkets LJ | Phospholipid directed motility of surface-motile bacteria. | 2006 | Mol. Microbiol. | pmid:16925549 |
| Matsumoto K et al. | Lipid domains in bacterial membranes. | 2006 | Mol. Microbiol. | pmid:16925550 |
| Bonner PJ et al. | FibA and PilA act cooperatively during fruiting body formation of Myxococcus xanthus. | 2006 | Mol. Microbiol. | pmid:16925559 |
| Sokol DK et al. | Obsessive-compulsive disorder and central nervous system autoimmunity. | 2006 | Br J Psychiatry | pmid:16880498 |
| Hidalgo FJ et al. | Antioxidative activity of amino phospholipids and phospholipid/amino Acid mixtures in edible oils as determined by the Rancimat method. | 2006 | J. Agric. Food Chem. | pmid:16848532 |
| Giles I et al. | Arginine residues are important in determining the binding of human monoclonal antiphospholipid antibodies to clinically relevant antigens. | 2006 | J. Immunol. | pmid:16849482 |
| Xu Y et al. | A Drosophila model of Barth syndrome. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16855048 |
| Takahashi K et al. | Purification and ATPase activity of human ABCA1. | 2006 | J. Biol. Chem. | pmid:16500904 |
| Petelska AD et al. | The interfacial tension of the lipid membrane formed from lipid-cholesterol and lipid-lipid systems. | 2006 | Cell Biochem. Biophys. | pmid:16456222 |
| Clark MC et al. | NMR assignment of rat Raf kinase inhibitor protein. | 2006 | J. Biomol. NMR | pmid:16456706 |
| Oberfeld B et al. | Phospholipids occupy the internal lumen of the c ring of the ATP synthase of Escherichia coli. | 2006 | Biochemistry | pmid:16460030 |
| Wachtel E et al. | A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes. | 2006 | Biochemistry | pmid:16430232 |
| Shizuka M et al. | Synthesis of isoprostanyl phosphatidylcholine and isoprostanyl phosphatidylethanolamine. | 2006 | J. Org. Chem. | pmid:16468779 |
| Higuchi O et al. | Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor. | 2006 | J. Lipid Res. | pmid:16470027 |
| Yoon SJ et al. | Interaction of N-linked glycans, having multivalent GlcNAc termini, with GM3 ganglioside. | 2006 | Glycoconj. J. | pmid:17115280 |
| Pernet F et al. | Comparison of three solid-phase extraction methods for fatty acid analysis of lipid fractions in tissues of marine bivalves. | 2006 | J Chromatogr A | pmid:17097094 |
| Tanaka A et al. | Peroxisome division is impaired in a CHO cell mutant with an inactivating point-mutation in dynamin-like protein 1 gene. | 2006 | Exp. Cell Res. | pmid:16529741 |
| Dabholkar RD et al. | Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. | 2006 | Int J Pharm | pmid:16616818 |
| Shaikh SR et al. | Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state 2H NMR reveal differences with phosphatidylcholines. | 2006 | J. Am. Chem. Soc. | pmid:16620109 |
| Ishida BY et al. | High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture. | 2006 | Br J Ophthalmol | pmid:16622093 |
| Hincha DK | High concentrations of the compatible solute glycinebetaine destabilize model membranes under stress conditions. | 2006 | Cryobiology | pmid:16696965 |
| Xie J et al. | Phosphatidylethanolamine and monoglucosyldiacylglycerol are interchangeable in supporting topogenesis and function of the polytopic membrane protein lactose permease. | 2006 | J. Biol. Chem. | pmid:16698795 |
| Separovic D et al. | Ceramide response post-photodamage is absent after treatment with HA14-1. | 2006 | Biochem. Biophys. Res. Commun. | pmid:16701558 |
| Russano AM et al. | Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. | 2006 | J. Allergy Clin. Immunol. | pmid:16675349 |
| Li Z et al. | The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. | 2006 | Cell Metab. | pmid:16679290 |
| Sternin E et al. | Changes in molecular order across the lamellar-to-inverted hexagonal phase transition depend on the position of the double-bond in mono-unsaturated phospholipid dispersions. | 2006 | Chem. Phys. Lipids | pmid:16574088 |
| Buzón V and Cladera J | Effect of cholesterol on the interaction of the HIV GP41 fusion peptide with model membranes. Importance of the membrane dipole potential. | 2006 | Biochemistry | pmid:17176099 |
| Kume H and Sasaki H | Ethanolamine modulates DNA synthesis through epidermal growth factor receptor in rat primary hepatocytes. | 2006 Jan-Feb | In Vitro Cell. Dev. Biol. Anim. | pmid:16618207 |
| Sawant RM et al. | "SMART" drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers. | 2006 Jul-Aug | Bioconjug. Chem. | pmid:16848401 |
| Dubielecka PM et al. | Mitoxantrone changes spectrin-aminophospholipid interactions. | 2006 May-Jun | Mol. Membr. Biol. | pmid:16785207 |
| Mizugishi K et al. | Maternal disturbance in activated sphingolipid metabolism causes pregnancy loss in mice. | 2007 | J. Clin. Invest. | pmid:17885683 |
| Sanmarco M et al. | Antigenic profile, prevalence, and clinical significance of antiphospholipid antibodies in women referred for in vitro fertilization. | 2007 | Ann. N. Y. Acad. Sci. | pmid:17894010 |
| Riekhof WR et al. | Lysophosphatidylcholine metabolism in Saccharomyces cerevisiae: the role of P-type ATPases in transport and a broad specificity acyltransferase in acylation. | 2007 | J. Biol. Chem. | pmid:17951629 |
| Lelliott CJ et al. | Hepatic PGC-1beta overexpression induces combined hyperlipidemia and modulates the response to PPARalpha activation. | 2007 | Arterioscler. Thromb. Vasc. Biol. | pmid:17932310 |
| Miyamoto S and Tokuda H | Diverse effects of phospholipids on lipoprotein sorting and ATP hydrolysis by the ABC transporter LolCDE complex. | 2007 | Biochim. Biophys. Acta | pmid:17498646 |
| Wydro P and Hac-Wydro K | Thermodynamic description of the interactions between lipids in ternary Langmuir monolayers: the study of cholesterol distribution in membranes. | 2007 | J Phys Chem B | pmid:17315916 |
| Subramani S and Farré JC | A ubiquitin-like protein involved in membrane fusion. | 2007 | Cell | pmid:17632052 |
| Nakatogawa H et al. | Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. | 2007 | Cell | pmid:17632063 |
| Zhu X et al. | Regulation of eosinophil adhesion by lysophosphatidylcholine via a non-store-operated Ca2+ channel. | 2007 | Am. J. Respir. Cell Mol. Biol. | pmid:17218614 |
| Stark B et al. | Association of vasoactive intestinal peptide with polymer-grafted liposomes: structural aspects for pulmonary delivery. | 2007 | Biochim. Biophys. Acta | pmid:17204237 |
| Grossfield A et al. | Convergence of molecular dynamics simulations of membrane proteins. | 2007 | Proteins | pmid:17243153 |
| Aranda FJ et al. | Thermodynamics of the interaction of a dirhamnolipid biosurfactant secreted by Pseudomonas aeruginosa with phospholipid membranes. | 2007 | Langmuir | pmid:17243729 |
| Matsushita M et al. | Structure of Atg5.Atg16, a complex essential for autophagy. | 2007 | J. Biol. Chem. | pmid:17192262 |