| MeSH term | MeSH ID | Detail |
|---|---|---|
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Simard JR et al. | Fatty acid flip-flop in a model membrane is faster than desorption into the aqueous phase. | 2008 | Biochemistry | pmid:18693753 |
| Wang Y et al. | Regulation of signal peptidase by phospholipids in membrane: characterization of phospholipid bilayer incorporated Escherichia coli signal peptidase. | 2004 | Biochemistry | pmid:14705954 |
| Kim KH et al. | Membrane properties induced by anionic phospholipids and phosphatidylethanolamine are critical for the membrane binding and catalytic activity of human cytochrome P450 3A4. | 2003 | Biochemistry | pmid:14690448 |
| Goss R et al. | Role of hexagonal structure-forming lipids in diadinoxanthin and violaxanthin solubilization and de-epoxidation. | 2005 | Biochemistry | pmid:15751979 |
| Fanani ML et al. | Lipid modulation of the activity of diacylglycerol kinase alpha- and zeta-isoforms: activation by phosphatidylethanolamine and cholesterol. | 2004 | Biochemistry | pmid:15544347 |
| Kobayashi S et al. | Membrane translocation mechanism of the antimicrobial peptide buforin 2. | 2004 | Biochemistry | pmid:15581374 |
| Avrahami D and Shai Y | Bestowing antifungal and antibacterial activities by lipophilic acid conjugation to D,L-amino acid-containing antimicrobial peptides: a plausible mode of action. | 2003 | Biochemistry | pmid:14674771 |
| Ahn T et al. | Involvement of nonlamellar-prone lipids in the stability increase of human cytochrome P450 1A2 in reconstituted membranes. | 2005 | Biochemistry | pmid:15966743 |
| Oberfeld B et al. | Phospholipids occupy the internal lumen of the c ring of the ATP synthase of Escherichia coli. | 2006 | Biochemistry | pmid:16460030 |
| Wachtel E et al. | A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes. | 2006 | Biochemistry | pmid:16430232 |
| Monje-Galvan V and Klauda JB | Modeling Yeast Organelle Membranes and How Lipid Diversity Influences Bilayer Properties. | 2015 | Biochemistry | pmid:26497753 |
| Buzón V and Cladera J | Effect of cholesterol on the interaction of the HIV GP41 fusion peptide with model membranes. Importance of the membrane dipole potential. | 2006 | Biochemistry | pmid:17176099 |
| Bradley RM et al. | Lpaatδ/Agpat4 deficiency impairs maximal force contractility in soleus and alters fibre type in extensor digitorum longus muscle. | 2018 | Biochim Biophys Acta Mol Cell Biol Lipids | pmid:29627383 |
| Mokhtarieh AA et al. | Asymmetric liposome particles with highly efficient encapsulation of siRNA and without nonspecific cell penetration suitable for target-specific delivery. | 2012 | Biochim. Biophys. Acta | pmid:22465072 |
| Vieler A et al. | The influence of phase transitions in phosphatidylethanolamine models on the activity of violaxanthin de-epoxidase. | 2008 | Biochim. Biophys. Acta | pmid:18178148 |
| Zhirnov AE et al. | Lipid composition determines interaction of liposome membranes with Pluronic L61. | 2005 | Biochim. Biophys. Acta | pmid:16405999 |
| Uyama T et al. | Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes. | 2009 | Biochim. Biophys. Acta | pmid:19615464 |
| Gabrys CM et al. | Nuclear magnetic resonance evidence for retention of a lamellar membrane phase with curvature in the presence of large quantities of the HIV fusion peptide. | 2010 | Biochim. Biophys. Acta | pmid:19616505 |
| Lairion F and Disalvo EA | Effect of arbutin on the dipole potential and area per lipid of ester and ether phosphatidylcholine and phosphatidyl ethanolamine monolayers. | 2007 | Biochim. Biophys. Acta | pmid:17257579 |
| Marconescu A and Thorpe PE | Coincident exposure of phosphatidylethanolamine and anionic phospholipids on the surface of irradiated cells. | 2008 | Biochim. Biophys. Acta | pmid:18570887 |