PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Venous Thromboembolism D054556 2 associated lipids
Barth Syndrome D056889 3 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Paran CW et al. Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy. 2015 Biochim. Biophys. Acta pmid:26361872
Vrablik TL et al. Lipidomic and proteomic analysis of Caenorhabditis elegans lipid droplets and identification of ACS-4 as a lipid droplet-associated protein. 2015 Biochim. Biophys. Acta pmid:26121959
Larson MC et al. Phosphatidylethanolamine is externalized at the surface of microparticles. 2012 Biochim. Biophys. Acta pmid:22960380
Epand RF et al. Bacterial lipid composition and the antimicrobial efficacy of cationic steroid compounds (Ceragenins). 2007 Biochim. Biophys. Acta pmid:17599802
Li Z et al. A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis. 2007 Biochim. Biophys. Acta pmid:17513168
Niebergall LJ and Vance DE The ratio of phosphatidylcholine to phosphatidylethanolamine does not predict integrity of growing MT58 Chinese hamster ovary cells. 2012 Biochim. Biophys. Acta pmid:22079326
Di Bartolomeo F et al. Involvement of a putative substrate binding site in the biogenesis and assembly of phosphatidylserine decarboxylase 1 from Saccharomyces cerevisiae. 2017 Biochim. Biophys. Acta pmid:28473294
Wang X et al. Arginine-lysine positional swap of the LL-37 peptides reveals evolutional advantages of the native sequence and leads to bacterial probes. 2017 Biochim. Biophys. Acta pmid:28450045
Vieler A et al. The influence of phase transitions in phosphatidylethanolamine models on the activity of violaxanthin de-epoxidase. 2008 Biochim. Biophys. Acta pmid:18178148
Guan Z et al. The polar lipids of Clostridium psychrophilum, an anaerobic psychrophile. 2013 Biochim. Biophys. Acta pmid:23454375
Zhirnov AE et al. Lipid composition determines interaction of liposome membranes with Pluronic L61. 2005 Biochim. Biophys. Acta pmid:16405999
Neumann J et al. Diverse relations between ABC transporters and lipids: An overview. 2017 Biochim. Biophys. Acta pmid:27693344
Di Bartolomeo F et al. Cell biology, physiology and enzymology of phosphatidylserine decarboxylase. 2017 Biochim. Biophys. Acta pmid:27650064
Willumeit R et al. Structural rearrangement of model membranes by the peptide antibiotic NK-2. 2005 Biochim. Biophys. Acta pmid:15893515
Ruhanen H et al. Depletion of TM6SF2 disturbs membrane lipid composition and dynamics in HuH7 hepatoma cells. 2017 Biochim. Biophys. Acta pmid:28434889
Goss R et al. Lipid dependence of diadinoxanthin solubilization and de-epoxidation in artificial membrane systems resembling the lipid composition of the natural thylakoid membrane. 2007 Biochim. Biophys. Acta pmid:16843433
Tasseva G et al. Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle. 2016 Biochim. Biophys. Acta pmid:26603903
Uyama T et al. Characterization of the human tumor suppressors TIG3 and HRASLS2 as phospholipid-metabolizing enzymes. 2009 Biochim. Biophys. Acta pmid:19615464
Gabrys CM et al. Nuclear magnetic resonance evidence for retention of a lamellar membrane phase with curvature in the presence of large quantities of the HIV fusion peptide. 2010 Biochim. Biophys. Acta pmid:19616505
Carmona-Antoñanzas G et al. Molecular mechanism of dietary phospholipid requirement of Atlantic salmon, Salmo salar, fry. 2015 Biochim. Biophys. Acta pmid:26303578