MeSH term | MeSH ID | Detail |
---|---|---|
Iron Overload | D019190 | 11 associated lipids |
Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Bernoud-Hubac N et al. | Covalent binding of isoketals to ethanolamine phospholipids. | 2004 | Free Radic. Biol. Med. | pmid:15477011 |
Alves ID et al. | Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy. | 2005 | Biophys. J. | pmid:15501933 |
Sostarecz AG et al. | Phosphatidylethanolamine-induced cholesterol domains chemically identified with mass spectrometric imaging. | 2004 | J. Am. Chem. Soc. | pmid:15506723 |
Elmes M et al. | The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. | 2004 | Biochim. Biophys. Acta | pmid:15522830 |
Fanani ML et al. | Lipid modulation of the activity of diacylglycerol kinase alpha- and zeta-isoforms: activation by phosphatidylethanolamine and cholesterol. | 2004 | Biochemistry | pmid:15544347 |
Riché EL et al. | Novel long-circulating liposomes containing peptide library-lipid conjugates: synthesis and in vivo behavior. | 2004 | J Drug Target | pmid:15545085 |
Murzyn K et al. | Phosphatidylethanolamine-phosphatidylglycerol bilayer as a model of the inner bacterial membrane. | 2005 | Biophys. J. | pmid:15556990 |
Kobayashi S et al. | Membrane translocation mechanism of the antimicrobial peptide buforin 2. | 2004 | Biochemistry | pmid:15581374 |
Zhai X et al. | Small angle X-ray scattering (SAXS) and differential scanning calorimetry (DSC) studies of amide phospholipids. | 2005 | Chem. Phys. Lipids | pmid:15589228 |
Ho SY et al. | Lipid metabolism in zebrafish. | 2004 | Methods Cell Biol. | pmid:15602873 |
Jernigan Jr HM et al. | Effects of cataractogenesis on the CDP-choline pathway: increased phospholipid synthesis in lenses from galactosemic rats and 13/N guinea pigs. | 2005 Jan-Feb | Ophthalmic Res. | pmid:15604593 |
Edwards IJ et al. | Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin. | 2004 | Clin. Cancer Res. | pmid:15623603 |
Nguyen LT et al. | Structural studies and model membrane interactions of two peptides derived from bovine lactoferricin. | 2005 | J. Pept. Sci. | pmid:15635665 |
Kamimori H et al. | Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. | 2005 | Anal. Biochem. | pmid:15649388 |
Sabah J et al. | Role of albumin as a fatty acid carrier for biosynthesis of lens lipids. | 2005 | Exp. Eye Res. | pmid:15652523 |
Sato Y et al. | Transformation of Escherichia coli mediated by natural phospholipids. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15665495 |
Wang C et al. | Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. | 2004 | Se Pu | pmid:15709398 |
Musiol HJ et al. | Toward semisynthetic lipoproteins by convergent strategies based on click and ligation chemistry. | 2005 | Chembiochem | pmid:15723440 |
Nishibori A et al. | Phosphatidylethanolamine domains and localization of phospholipid synthases in Bacillus subtilis membranes. | 2005 | J. Bacteriol. | pmid:15743965 |
Goss R et al. | Role of hexagonal structure-forming lipids in diadinoxanthin and violaxanthin solubilization and de-epoxidation. | 2005 | Biochemistry | pmid:15751979 |