MeSH term | MeSH ID | Detail |
---|---|---|
Iron Overload | D019190 | 11 associated lipids |
Barth Syndrome | D056889 | 3 associated lipids |
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Khopade AJ et al. | Phase structures of a hydrated anionic phospholipid composition containing cationic dendrimers and pegylated lipids. | 2004 | Langmuir | pmid:15323476 |
Odabaei G et al. | Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis. | 2004 | Adv. Cancer Res. | pmid:15327891 |
Iwamoto K et al. | [Relationship between localized phosphatidylethanolamine exposure and yeast cell polarity]. | 2004 | Tanpakushitsu Kakusan Koso | pmid:15346886 |
Boumann HA et al. | The yeast phospholipid N-methyltransferases catalyzing the synthesis of phosphatidylcholine preferentially convert di-C16:1 substrates both in vivo and in vitro. | 2004 | J. Biol. Chem. | pmid:15258140 |
Laurinavicius S et al. | The origin of phospholipids of the enveloped bacteriophage phi6. | 2004 | Virology | pmid:15262506 |
Sugi T et al. | Antiphosphatidylethanolamine antibodies in recurrent early pregnancy loss and mid-to-late pregnancy loss. | 2004 | J. Obstet. Gynaecol. Res. | pmid:15238112 |
Demana PH et al. | Incorporation of ovalbumin into ISCOMs and related colloidal particles prepared by the lipid film hydration method. | 2004 | Int J Pharm | pmid:15196631 |
Liu F et al. | Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers. | 2004 | Biophys. J. | pmid:15454444 |
Riché EL et al. | Novel long-circulating liposomes containing peptide library-lipid conjugates: synthesis and in vivo behavior. | 2004 | J Drug Target | pmid:15545085 |
Berson EL et al. | Further evaluation of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment: subgroup analyses. | 2004 | Arch. Ophthalmol. | pmid:15364709 |
Bernoud-Hubac N et al. | Covalent binding of isoketals to ethanolamine phospholipids. | 2004 | Free Radic. Biol. Med. | pmid:15477011 |
Li SY et al. | [Cell membrane phospholipid variation and protein kinase C expression effects on hepatic metastasis of large intestinal carcinoma]. | 2004 | Zhonghua Wai Ke Za Zhi | pmid:15009987 |
Montes LR et al. | Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes. | 2004 | Biochemistry | pmid:15035639 |
Dennis MW et al. | Prothrombinase enhancement through quantitative and qualitative changes affecting very low density lipoprotein in complex with C-reactive protein. | 2004 | Thromb. Haemost. | pmid:14983228 |
Darville T et al. | Protection against Chlamydia trachomatis infection in vitro and modulation of inflammatory response in vivo by membrane-bound glycosaminoglycans. | 2004 | Microbes Infect. | pmid:15050964 |
Schleheck D et al. | Parvibaculum lavamentivorans gen. nov., sp. nov., a novel heterotroph that initiates catabolism of linear alkylbenzenesulfonate. | 2004 | Int. J. Syst. Evol. Microbiol. | pmid:15388700 |
Elmes M et al. | The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. | 2004 | Biochim. Biophys. Acta | pmid:15522830 |
Trajkovic-Bodennec S et al. | Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes. | 2004 Jul-Aug | Blood Cells Mol. Dis. | pmid:15223015 |
Vasil'eva OB et al. | [Biochemical properties of the the lipoproteins lipid composition in fishes of the different ecology: trout Salmo irideus L. and whitefish Coregonus lavaretus L]. | 2004 Mar-Apr | Izv. Akad. Nauk. Ser. Biol. | pmid:15131975 |
Malisiova F et al. | Liposomal formulations from phospholipids of Greek almond oil. Properties and biological activity. | 2004 May-Jun | Z. Naturforsch., C, J. Biosci. | pmid:18998396 |