| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Xiao S et al. | Overexpression of Arabidopsis acyl-CoA binding protein ACBP3 promotes starvation-induced and age-dependent leaf senescence. | 2010 | Plant Cell | pmid:20442372 |
| Otsuru M et al. | Mitochondrial phosphatidylethanolamine level modulates Cyt c oxidase activity to maintain respiration capacity in Arabidopsis thaliana rosette leaves. | 2013 | Plant Cell Physiol. | pmid:23872271 |
| Yoshida K et al. | Studies on vacuolar membrane microdomains isolated from Arabidopsis suspension-cultured cells: local distribution of vacuolar membrane proteins. | 2013 | Plant Cell Physiol. | pmid:23903016 |
| Yunus IS et al. | The importance of SERINE DECARBOXYLASE1 (SDC1) and ethanolamine biosynthesis during embryogenesis of Arabidopsis thaliana. | 2016 | Plant J. | pmid:27436233 |
| Gaude N et al. | Phospholipase C5 (NPC5) is involved in galactolipid accumulation during phosphate limitation in leaves of Arabidopsis. | 2008 | Plant J. | pmid:18564386 |
| Burgos A et al. | Analysis of short-term changes in the Arabidopsis thaliana glycerolipidome in response to temperature and light. | 2011 | Plant J. | pmid:21309866 |
| Sutoh K et al. | Specific induction of TaAAPT1, an ER- and Golgi-localized ECPT-type aminoalcoholphosphotransferase, results in preferential accumulation of the phosphatidylethanolamine membrane phospholipid during cold acclimation in wheat. | 2010 | Plant Mol. Biol. | pmid:20024669 |
| Nerlich A et al. | Deficiency in phosphatidylserine decarboxylase activity in the psd1 psd2 psd3 triple mutant of Arabidopsis affects phosphatidylethanolamine accumulation in mitochondria. | 2007 | Plant Physiol. | pmid:17449644 |
| Fan J et al. | A Central Role for Triacylglycerol in Membrane Lipid Breakdown, Fatty Acid -Oxidation, and Plant Survival under Extended Darkness. | 2017 | Plant Physiol. | pmid:28572457 |
| Chung T et al. | The ATG autophagic conjugation system in maize: ATG transcripts and abundance of the ATG8-lipid adduct are regulated by development and nutrient availability. | 2009 | Plant Physiol. | pmid:18790996 |
| Vu HS et al. | Direct infusion mass spectrometry of oxylipin-containing Arabidopsis membrane lipids reveals varied patterns in different stress responses. | 2012 | Plant Physiol. | pmid:22086419 |
| Hocquellet A et al. | Evidence for a different metabolism of PC and PE in shoots and roots. | 2005 Oct-Nov | Plant Physiol. Biochem. | pmid:16325411 |
| Bakken AM et al. | Glycerophospholipid molecular species in platelets and brain tissues - are platelets a good model for neurons? | 2006 | Platelets | pmid:17074725 |
| Xu K and Nagy PD | Enrichment of Phosphatidylethanolamine in Viral Replication Compartments via Co-opting the Endosomal Rab5 Small GTPase by a Positive-Strand RNA Virus. | 2016 | PLoS Biol. | pmid:27760128 |
| Fei W et al. | A role for phosphatidic acid in the formation of "supersized" lipid droplets. | 2011 | PLoS Genet. | pmid:21829381 |
| Wei W et al. | Defining ICR-Mo, an intrinsic colistin resistance determinant from Moraxella osloensis. | 2018 | PLoS Genet. | pmid:29758020 |
| Patel N et al. | A novel three serum phospholipid panel differentiates normal individuals from those with prostate cancer. | 2014 | PLoS ONE | pmid:24603597 |
| Maniti O et al. | Distinct behaviour of the homeodomain derived cell penetrating peptide penetratin in interaction with different phospholipids. | 2010 | PLoS ONE | pmid:21209890 |
| Dixit AK and Jayabaskaran C | Phospholipid mediated activation of calcium dependent protein kinase 1 (CaCDPK1) from chickpea: a new paradigm of regulation. | 2012 | PLoS ONE | pmid:23284721 |
| Sabharwal T et al. | Defense related decadienal elicits membrane lipid remodeling in the diatom Phaeodactylum tricornutum. | 2017 | PLoS ONE | pmid:28582415 |