| MeSH term | MeSH ID | Detail |
|---|---|---|
| Abortion, Spontaneous | D000022 | 12 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Cardiomyopathy, Dilated | D002311 | 15 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Choline Deficiency | D002796 | 16 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Serrán-Aguilera L et al. | Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death. | 2016 | Sci Rep | pmid:27616047 |
| Ma K et al. | Bacillus vini sp. nov. isolated from alcohol fermentation pit mud. | 2016 | Arch. Microbiol. | pmid:27055557 |
| Kojima R et al. | A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro. | 2016 | Sci Rep | pmid:27469264 |
| Abd-Elhadi S et al. | Total α-synuclein levels in human blood cells, CSF, and saliva determined by a lipid-ELISA. | 2016 | Anal Bioanal Chem | pmid:27624766 |
| Park S et al. | Algoriphagus litorisediminis sp. nov., isolated from a tidal flat. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27707431 |
| Arvind TA and Rangarajan PN | Mouse Apolipoprotein L9 is a phosphatidylethanolamine-binding protein. | 2016 | Biochem. Biophys. Res. Commun. | pmid:27697524 |
| Wang H et al. | Carboxylicivirga flava sp. nov., isolated from marine surface sediment. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27692034 |
| Subhash Y et al. | Microvirgula curvata sp. nov., isolated from hydrocarbon-contaminated soil, and emended description of the genus Microvirgula. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27666417 |
| Divyasree B et al. | Description of Lunatimonas salinarum sp. nov. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27638361 |
| Broughton LJ et al. | Duramycin-porphyrin conjugates for targeting of tumour cells using photodynamic therapy. | 2016 | J. Photochem. Photobiol. B, Biol. | pmid:27619739 |
| Park S et al. | Pontibacter litorisediminis sp. nov., isolated from a tidal flat. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27469111 |
| Kim SJ et al. | Pseudoflavitalea rhizosphaerae gen. nov., sp. nov., isolated from rhizosphere of tomato, and proposal to reclassify Flavitalea soli as Pseudoflavitalea soli comb. nov. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27469002 |
| Guo W et al. | Chryseobacterium montanum sp. nov. isolated from mountain soil. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27412503 |
| Liu K et al. | Hymenobacter glacieicola sp. nov., isolated from glacier ice. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27374800 |
| Kim DH et al. | Flavobacterium panacis sp. nov., isolated from rhizosphere of Panax ginseng. | 2016 | Antonie Van Leeuwenhoek | pmid:27357576 |
| Newsom SA et al. | Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans. | 2016 | J. Appl. Physiol. | pmid:27032901 |
| Trinh H and Yi TH | Pedobacter humi sp. nov., isolated from a playground soil. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27032079 |
| Lee K et al. | Paradonghicola geojensis gen. nov., sp. nov., isolated from seawater, Geoje-si, South Korea. | 2016 | Arch. Microbiol. | pmid:26971334 |
| Suwannachart C et al. | Flavobacterium tistrianum sp. nov., a gliding bacterium isolated from soil. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:26970735 |
| Tasseva G et al. | Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle. | 2016 | Biochim. Biophys. Acta | pmid:26603903 |
| Han L et al. | Tianweitania sediminis gen. nov., sp. nov., a member of the family Phyllobacteriaceae, isolated from subsurface sediment core. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:26597787 |
| Takano T et al. | Ichthyobacterium seriolicida gen. nov., sp. nov., a member of the phylum 'Bacteroidetes', isolated from yellowtail fish (Seriola quinqueradiata) affected by bacterial haemolytic jaundice, and proposal of a new family, Ichthyobacteriaceae fam. nov. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:26554606 |
| Yang SH et al. | Pseudofulvibacter gastropodicola sp. nov., isolated from a marine conch and emended descriptions of the genus Pseudofulvibacter Yoon et al. 2013 and Pseudofulvibacter geojedonensis. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:26537663 |
| Sun J et al. | Ultrasound-mediated destruction of oxygen and paclitaxel loaded lipid microbubbles for combination therapy in hypoxic ovarian cancer cells. | 2016 | Ultrason Sonochem | pmid:26384914 |
| Bernhard W et al. | Developmental changes in polyunsaturated fetal plasma phospholipids and feto-maternal plasma phospholipid ratios and their association with bronchopulmonary dysplasia. | 2016 | Eur J Nutr | pmid:26363610 |
| Zhang J et al. | The influence of different long-circulating materials on the pharmacokinetics of liposomal vincristine sulfate. | 2016 | Int J Nanomedicine | pmid:27616886 |
| Aydogan EL et al. | Proposal of Mucilaginibacter phyllosphaerae sp. nov. isolated from the phyllosphere of Galium album. | 2016 | Int. J. Syst. Evol. Microbiol. | pmid:27468703 |
| Chidley C et al. | The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine. | 2016 | Elife | pmid:27403889 |
| Miyata N et al. | Phosphatidylserine transport by Ups2-Mdm35 in respiration-active mitochondria. | 2016 | J. Cell Biol. | pmid:27354379 |
| Casado F et al. | Location and Effects of an Antitumoral Catechin on the Structural Properties of Phosphatidylethanolamine Membranes. | 2016 | Molecules | pmid:27347914 |
| Guo J et al. | Efficient Quantitative Analysis of Carboxyalkylpyrrole Ethanolamine Phospholipids: Elevated Levels in Sickle Cell Disease Blood. | 2016 | Chem. Res. Toxicol. | pmid:27341308 |
| Park JM et al. | The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. | 2016 | Autophagy | pmid:27046250 |
| Dimitrova M et al. | CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition. | 2016 | Sci Rep | pmid:27040328 |
| Luo R et al. | Monitoring Apoptosis of Breast Cancer Xenograft After Paclitaxel Treatment With 99mTc-Labeled Duramycin SPECT/CT. | 2016 | Mol Imaging | pmid:27030401 |
| Biswas S et al. | Novel phosphatidylethanolamine derivatives accumulate in circulation in hyperlipidemic ApoE-/- mice and activate platelets via TLR2. | 2016 | Blood | pmid:27015965 |
| Fahrmann JF et al. | Serum phosphatidylethanolamine levels distinguish benign from malignant solitary pulmonary nodules and represent a potential diagnostic biomarker for lung cancer. | 2016 | Cancer Biomark | pmid:27002763 |
| Bascoul-Colombo C et al. | Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease. | 2016 | Biochim. Biophys. Acta | pmid:26968097 |
| Sharma S et al. | A Coarse Grained Model for a Lipid Membrane with Physiological Composition and Leaflet Asymmetry. | 2015 | PLoS ONE | pmid:26659855 |
| Lind TK et al. | Formation and Characterization of Supported Lipid Bilayers Composed of Hydrogenated and Deuterated Escherichia coli Lipids. | 2015 | PLoS ONE | pmid:26658241 |
| Thukral L et al. | The Molecular Mechanism Underlying Recruitment and Insertion of Lipid-Anchored LC3 Protein into Membranes. | 2015 | Biophys. J. | pmid:26588566 |
| Farine L et al. | Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei. | 2015 | Sci Rep | pmid:26577437 |
| Richard AS et al. | Virion-associated phosphatidylethanolamine promotes TIM1-mediated infection by Ebola, dengue, and West Nile viruses. | 2015 | Proc. Natl. Acad. Sci. U.S.A. | pmid:26575624 |
| Rojas-Betancourt S et al. | Gas-Phase Chemical Separation of Phosphatidylcholine and Phosphatidylethanolamine Cations via Charge Inversion Ion/Ion Chemistry. | 2015 | Anal. Chem. | pmid:26477819 |
| Carnec X et al. | The Phosphatidylserine and Phosphatidylethanolamine Receptor CD300a Binds Dengue Virus and Enhances Infection. | 2015 | J. Virol. | pmid:26468529 |
| Bagalkot V et al. | Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals. | 2015 | J Control Release | pmid:26386437 |
| Finger S et al. | The efficacy of trivalent cyclic hexapeptides to induce lipid clustering in PG/PE membranes correlates with their antimicrobial activity. | 2015 | Biochim. Biophys. Acta | pmid:26367060 |
| Paran CW et al. | Lipogenesis mitigates dysregulated sarcoplasmic reticulum calcium uptake in muscular dystrophy. | 2015 | Biochim. Biophys. Acta | pmid:26361872 |
| Sanchez-Alvarez M et al. | Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis. | 2015 | Open Biol | pmid:26333836 |
| Leite NB et al. | PE and PS Lipids Synergistically Enhance Membrane Poration by a Peptide with Anticancer Properties. | 2015 | Biophys. J. | pmid:26331251 |
| Soupene E and Kuypers FA | Ligand binding to the ACBD6 protein regulates the acyl-CoA transferase reactions in membranes. | 2015 | J. Lipid Res. | pmid:26290611 |
| Kerrinnes T et al. | Phospholipase A1 modulates the cell envelope phospholipid content of Brucella melitensis, contributing to polymyxin resistance and pathogenicity. | 2015 | Antimicrob. Agents Chemother. | pmid:26282427 |
| Henriques ST et al. | The Prototypic Cyclotide Kalata B1 Has a Unique Mechanism of Entering Cells. | 2015 | Chem. Biol. | pmid:26278183 |
| Matyjaszkiewicz A et al. | Subconductance gating and voltage sensitivity of sarcoplasmic reticulum K(+) channels: a modeling approach. | 2015 | Biophys. J. | pmid:26200862 |
| Belov GA | Less Grease, Please. Phosphatidylethanolamine Is the Only Lipid Required for Replication of a (+)RNA Virus. | 2015 | Viruses | pmid:26131959 |
| Vrablik TL et al. | Lipidomic and proteomic analysis of Caenorhabditis elegans lipid droplets and identification of ACS-4 as a lipid droplet-associated protein. | 2015 | Biochim. Biophys. Acta | pmid:26121959 |
| Alirezaei M et al. | Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo. | 2015 | Autophagy | pmid:26090585 |
| Sarabipour S et al. | Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation. | 2015 | Biochim. Biophys. Acta | pmid:25896659 |
| Vicente EF et al. | N-terminal microdomain peptide from human dihydroorotate dehydrogenase: structure and model membrane interactions. | 2015 | Protein Pept. Lett. | pmid:24810226 |
| Nurkanto A et al. | Cryptosporangium cibodasense sp. nov., isolated from leaf litter in Indonesia. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26395204 |
| Wang Y et al. | Structure characterization of phospholipids and lipid A of Pseudomonas putida KT2442. | 2015 | Eur J Mass Spectrom (Chichester) | pmid:26579930 |
| Reichel M et al. | Alterations of plasma glycerophospholipid and sphingolipid species in male alcohol-dependent patients. | 2015 | Biochim. Biophys. Acta | pmid:26291032 |
| Svensson E et al. | Compound-specific stable isotope analysis of nitrogen-containing intact polar lipids. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26522319 |
| Park SH et al. | Flavobacterium jejuensis sp. nov., isolated from marine brown alga Ecklonia cava. | 2015 | J. Microbiol. | pmid:26502959 |
| Joo ES et al. | Spirosoma pulveris sp. nov., a bacterium isolated from a dust sample collected at Chungnam province, South Korea. | 2015 | J. Microbiol. | pmid:26502958 |
| Monje-Galvan V and Klauda JB | Modeling Yeast Organelle Membranes and How Lipid Diversity Influences Bilayer Properties. | 2015 | Biochemistry | pmid:26497753 |
| Zhou L et al. | Identification of Oxidation Compounds of 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine during Thermal Oxidation. | 2015 | J. Agric. Food Chem. | pmid:26478449 |
| Song J et al. | Aurantivirga profunda gen. nov., sp. nov., isolated from deep-seawater, a novel member of the family Flavobacteriaceae. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26443199 |
| Bradley RM et al. | Acylglycerophosphate acyltransferase 4 (AGPAT4) is a mitochondrial lysophosphatidic acid acyltransferase that regulates brain phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol levels. | 2015 | Biochim. Biophys. Acta | pmid:26417903 |
| Lageix F et al. | [Association between the presence of antiphospholipid antibodies and the occurrence of autism spectrum disorder in childhood]. | 2015 | Arch Pediatr | pmid:26386813 |
| Tanaka R et al. | Formosa haliotis sp. nov., a brown-alga-degrading bacterium isolated from the gut of the abalone Haliotis gigantea. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26354496 |
| Wei F et al. | Assembly and relaxation behaviours of phosphatidylethanolamine monolayers investigated by polarization and frequency resolved SFG-VS. | 2015 | Phys Chem Chem Phys | pmid:26349673 |
| Song L et al. | Belliella marina sp. nov., isolated from seawater. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26346194 |
| Liu L et al. | Hymenobacter mucosus sp. nov., isolated from a karst cave soil sample. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26303395 |
| Liu QQ et al. | Saccharicrinis marinus sp. nov., isolated from marine sediment. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26297337 |
| Sung HR et al. | Lewinella xylanilytica sp. nov., a member of the family Saprospiraceae isolated from coastal seawater. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26297220 |
| Kim HS et al. | Bizionia fulviae sp. nov., isolated from the gut of an egg cockle, Fulvia mutica. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26297143 |
| Park S et al. | Maribacter confluentis sp. nov., isolated from the junction between the ocean and a freshwater spring. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26297027 |
| Park S et al. | Alteromonas confluentis sp. nov., isolated from the junction between the ocean and a freshwater spring. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26296901 |
| Park S et al. | Pedobacter lignilitoris sp. nov., isolated from wood falls. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26296663 |
| Zhang Z et al. | Muricauda pacifica sp. nov., isolated from seawater of the South Pacific Gyre. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26294931 |
| Lin SY et al. | Chryseobacterium echinoideorum sp. nov., isolated from sea urchins (Tripneustes gratilla). | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26286270 |
| Kämpfer P et al. | Chryseobacterium sediminis sp. nov., isolated from a river sediment. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26283329 |
| Tang M et al. | Maribacter flavus sp. nov., isolated from a cyanobacterial culture pond. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26275889 |
| Nedashkovskaya OI et al. | Lutibacter holmesii sp. nov., a marine bacterium of the family Flavobacteriaceae isolated from the sea urchin Strongylocentrotus intermedius, and emended description of the genus Lutibacter. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26275791 |
| Ãlvarez R et al. | G protein-membrane interactions I: Gαi1 myristoyl and palmitoyl modifications in protein-lipid interactions and its implications in membrane microdomain localization. | 2015 | Biochim. Biophys. Acta | pmid:26253820 |
| Ge L et al. | Epilithonimonas psychrotolerans sp. nov., isolated from alpine permafrost. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26233482 |
| Zhang DC and Margesin R | Gelidibacter sediminis sp. nov., isolated from a sediment sample of the Yellow Sea. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26231542 |
| Schauss T et al. | Empedobacter stercoris sp. nov., isolated from an input sample of a biogas plant. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26228269 |
| Singh H et al. | Massilia arvi sp. nov., isolated from fallow-land soil previously cultivated with Brassica oleracea, and emended description of the genus Massilia. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26220552 |
| Nedashkovskaya OI et al. | Winogradskyella litoriviva sp. nov., isolated from coastal seawater. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26219946 |
| Amgalanbaatar A et al. | Phosphatidylethanolamine, but not Phosphatidylglycerol-Cardiolipin, Isolated from Two Species of Helicobacter Binds Cholesterol over Cholesteryl Ester. | 2015 | Lipids | pmid:26123694 |
| Aktas M and Narberhaus F | Unconventional membrane lipid biosynthesis in Xanthomonas campestris. | 2015 | Environ. Microbiol. | pmid:26119594 |
| Bălănescu P et al. | Association of anti phosphatidyl ethanolamine antibodies and low complement levels in systemic sclerosis patients--results of a cross-sectional study. | 2015 | Scand. J. Clin. Lab. Invest. | pmid:26067612 |
| Belkadhi A et al. | Exogenous salicylic acid protects phospholipids against cadmium stress in flax (Linum usitatissimum L.). | 2015 | Ecotoxicol. Environ. Saf. | pmid:26057076 |
| Kim YA et al. | Integration of Quercetin-Iron Complexes into Phosphatidylcholine or Phosphatidylethanolamine Liposomes. | 2015 | Appl. Biochem. Biotechnol. | pmid:26047928 |
| Du J et al. | Sphingobacterium mucilaginosum sp. nov., isolated from rhizosphere soil of a rose. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26023207 |
| Li H et al. | Bizionia arctica sp. nov., isolated from Arctic fjord seawater, and emended description of the genus Bizionia. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26016491 |
| Wang FQ et al. | Mariniphaga sediminis sp. nov., isolated from coastal sediment. | 2015 | Int. J. Syst. Evol. Microbiol. | pmid:26012581 |
| Sato Y et al. | Autoantibodies to Factor XII and Kininogen-Dependent Antiphosphatidylethanolamine Antibodies in Patients with Recurrent Pregnancy Loss Augment Platelet Aggregation. | 2015 | Am. J. Reprod. Immunol. | pmid:26011374 |
| Serna J et al. | Quantitative lipidomic analysis of plasma and plasma lipoproteins using MALDI-TOF mass spectrometry. | 2015 | Chem. Phys. Lipids | pmid:26004846 |