PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Abortion, Spontaneous D000022 12 associated lipids
Abortion, Habitual D000026 5 associated lipids
Adenocarcinoma D000230 166 associated lipids
Alzheimer Disease D000544 76 associated lipids
Cardiomyopathy, Dilated D002311 15 associated lipids
Cataract D002386 34 associated lipids
Cholestasis, Intrahepatic D002780 4 associated lipids
Choline Deficiency D002796 16 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Zhang N et al. [The enhancing effect of tomato lectin modified liposomes of insulin on oral absorption in mice]. 2004 Yao Xue Xue Bao pmid:15338884
Meuillet EJ et al. Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity. 2004 Arch. Biochem. Biophys. pmid:15313215
Moe MK et al. Vicinal hydroxylation of unsaturated fatty acids for structural characterization of intact neutral phospholipids by negative electrospray ionization tandem quadrupole mass spectrometry. 2004 Rapid Commun. Mass Spectrom. pmid:15317043
Sugai R et al. Overexpression of gnsA, a multicopy suppressor of the secG null mutation, increases acidic phospholipid contents by inhibiting phosphatidylethanolamine synthesis at low temperatures. 2004 J. Bacteriol. pmid:15317805
Wang X et al. A novel human phosphatidylethanolamine-binding protein resists tumor necrosis factor alpha-induced apoptosis by inhibiting mitogen-activated protein kinase pathway activation and phosphatidylethanolamine externalization. 2004 J. Biol. Chem. pmid:15302887
Doerrler WT et al. MsbA-dependent translocation of lipids across the inner membrane of Escherichia coli. 2004 J. Biol. Chem. pmid:15304478
Barker AP et al. A novel extracellular phospholipase C of Pseudomonas aeruginosa is required for phospholipid chemotaxis. 2004 Mol. Microbiol. pmid:15306013
Khopade AJ et al. Phase structures of a hydrated anionic phospholipid composition containing cationic dendrimers and pegylated lipids. 2004 Langmuir pmid:15323476
Odabaei G et al. Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis. 2004 Adv. Cancer Res. pmid:15327891
Iwamoto K et al. [Relationship between localized phosphatidylethanolamine exposure and yeast cell polarity]. 2004 Tanpakushitsu Kakusan Koso pmid:15346886
Zhang N et al. [Enhancing effect of Ulex europaeus agglutinin I modified liposomes on oral insulin absorption in mice]. 2004 Yao Xue Xue Bao pmid:15813031
Fanani ML et al. Lipid modulation of the activity of diacylglycerol kinase alpha- and zeta-isoforms: activation by phosphatidylethanolamine and cholesterol. 2004 Biochemistry pmid:15544347
Kobayashi S et al. Membrane translocation mechanism of the antimicrobial peptide buforin 2. 2004 Biochemistry pmid:15581374
Lairion F and Disalvo EA Effect of phloretin on the dipole potential of phosphatidylcholine, phosphatidylethanolamine, and phosphatidylglycerol monolayers. 2004 Langmuir pmid:15461500
Iwamoto K et al. Local exposure of phosphatidylethanolamine on the yeast plasma membrane is implicated in cell polarity. 2004 Genes Cells pmid:15461661
Sostarecz AG et al. Phosphatidylethanolamine-induced cholesterol domains chemically identified with mass spectrometric imaging. 2004 J. Am. Chem. Soc. pmid:15506723
Kihara A and Igarashi Y Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry. 2004 Mol. Biol. Cell pmid:15342785
Trajkovic-Bodennec S et al. Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes. 2004 Jul-Aug Blood Cells Mol. Dis. pmid:15223015
Vasil'eva OB et al. [Biochemical properties of the the lipoproteins lipid composition in fishes of the different ecology: trout Salmo irideus L. and whitefish Coregonus lavaretus L]. 2004 Mar-Apr Izv. Akad. Nauk. Ser. Biol. pmid:15131975
Malisiova F et al. Liposomal formulations from phospholipids of Greek almond oil. Properties and biological activity. 2004 May-Jun Z. Naturforsch., C, J. Biosci. pmid:18998396