| MeSH term | MeSH ID | Detail |
|---|---|---|
| Activated Protein C Resistance | D020016 | 1 associated lipids |
| Hamartoma Syndrome, Multiple | D006223 | 1 associated lipids |
| Sneddon Syndrome | D018860 | 1 associated lipids |
| Venous Thromboembolism | D054556 | 2 associated lipids |
| Barth Syndrome | D056889 | 3 associated lipids |
| Cholestasis, Intrahepatic | D002780 | 4 associated lipids |
| Chondrodysplasia Punctata, Rhizomelic | D018902 | 4 associated lipids |
| Abortion, Habitual | D000026 | 5 associated lipids |
| Trypanosomiasis | D014352 | 5 associated lipids |
| Galactosemias | D005693 | 5 associated lipids |
| Hyperhomocysteinemia | D020138 | 6 associated lipids |
| Trematode Infections | D014201 | 8 associated lipids |
| Tangier Disease | D013631 | 8 associated lipids |
| Bacteremia | D016470 | 9 associated lipids |
| Toxoplasmosis | D014123 | 9 associated lipids |
| Thinness | D013851 | 11 associated lipids |
| Fatty Liver, Alcoholic | D005235 | 11 associated lipids |
| Myocardial Ischemia | D017202 | 11 associated lipids |
| Iron Overload | D019190 | 11 associated lipids |
| Venous Thrombosis | D020246 | 11 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jumpsen JA et al. | Fatty acids in blood and intestine following docosahexaenoic acid supplementation in adults with cystic fibrosis. | 2006 | J. Cyst. Fibros. | pmid:16507353 |
| Carmieli R et al. | Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes. | 2006 | Biophys. J. | pmid:16258052 |
| Hamai C et al. | Effect of average phospholipid curvature on supported bilayer formation on glass by vesicle fusion. | 2006 | Biophys. J. | pmid:16299084 |
| Sou YS et al. | Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16. | 2006 | J. Biol. Chem. | pmid:16303767 |
| Lins L et al. | "De novo" design of peptides with specific lipid-binding properties. | 2006 | Biophys. J. | pmid:16275638 |
| Jin JK et al. | Phospholipase D1 is up-regulated in the mitochondrial fraction from the brains of Alzheimer's disease patients. | 2006 | Neurosci. Lett. | pmid:16973278 |
| Hicks AM et al. | Unique molecular signatures of glycerophospholipid species in different rat tissues analyzed by tandem mass spectrometry. | 2006 | Biochim. Biophys. Acta | pmid:16860597 |
| Tseng M et al. | Amycolatopsis taiwanensis sp. nov., from soil. | 2006 | Int. J. Syst. Evol. Microbiol. | pmid:16902013 |
| Tsuda T et al. | Effect of phosphatidylcholine, phosphatidylethanolamine and lysophosphatidylcholine on the protein C/protein S anticoagulation system. | 2006 | Blood Coagul. Fibrinolysis | pmid:16905948 |
| Tsuda T et al. | Effect of phosphatidylcholine, phosphatidylethanolamine and lysophosphatidylcholine on the activated factor X-prothrombin system. | 2006 | Blood Coagul. Fibrinolysis | pmid:16905950 |
| Gardiner C et al. | Detection of acquired resistance to activated protein C associated with antiphospholipid antibodies using a novel clotting assay. | 2006 | Blood Coagul. Fibrinolysis | pmid:16905952 |
| Welsh D et al. | Differential temperature acclimatization responses in the membrane phospholipids of Posthodiplostomum minimum and its second intermediate host, Lepomis macrochirus. | 2006 | J. Parasitol. | pmid:16995394 |
| Besson N et al. | Selective incorporation of docosahexaenoic acid into lysobisphosphatidic acid in cultured THP-1 macrophages. | 2006 | Lipids | pmid:17707985 |
| Oberfeld B et al. | Phospholipids occupy the internal lumen of the c ring of the ATP synthase of Escherichia coli. | 2006 | Biochemistry | pmid:16460030 |
| Wachtel E et al. | A product of ozonolysis of cholesterol alters the biophysical properties of phosphatidylethanolamine membranes. | 2006 | Biochemistry | pmid:16430232 |
| Shizuka M et al. | Synthesis of isoprostanyl phosphatidylcholine and isoprostanyl phosphatidylethanolamine. | 2006 | J. Org. Chem. | pmid:16468779 |
| Higuchi O et al. | Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor. | 2006 | J. Lipid Res. | pmid:16470027 |
| Blois A et al. | Interactions of chromogranin A-derived vasostatins and monolayers of phosphatidylserine, phosphatidylcholine and phosphatidylethanolamine. | 2006 | Regul. Pept. | pmid:16445995 |
| Alder-Baerens N et al. | Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. | 2006 | Mol. Biol. Cell | pmid:16452632 |
| Min Y et al. | A distinctive fatty acid profile in circulating lipids of Korean gestational diabetics: a pilot study. | 2006 | Diabetes Res. Clin. Pract. | pmid:16455150 |
| Tosch W et al. | Molecular species of phosphatidylethanolamine from continuous cultures of Saccharomyces pastorianus syn. carlsbergensis strains. | 2006 | Yeast | pmid:16491465 |
| Arnt L et al. | Membrane activity of biomimetic facially amphiphilic antibiotics. | 2006 | J Phys Chem B | pmid:16494408 |
| Bakken AM et al. | Glycerophospholipid molecular species in platelets and brain tissues - are platelets a good model for neurons? | 2006 | Platelets | pmid:17074725 |
| Mima J et al. | Specific membrane binding of the carboxypeptidase Y inhibitor I(C), a phosphatidylethanolamine-binding protein family member. | 2006 | FEBS J. | pmid:17076703 |
| Li LO et al. | Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes. | 2006 | J. Biol. Chem. | pmid:17028193 |
| Kume H et al. | Serum ethanolamine and hepatocyte proliferation in perinatal and partially hepatectomized rats. | 2006 | Life Sci. | pmid:16872638 |
| Salas JJ et al. | Phospholipid molecular profiles in the seed kernel from different sunflower (Helianthus annuus) mutants. | 2006 | Lipids | pmid:17120935 |
| Moon TC et al. | Ochnaflavone, naturally occurring biflavonoid, inhibits phospholipase A2 dependent phosphatidylethanolamine degradation in a CCl4-induced rat liver microsome. | 2006 | Biol. Pharm. Bull. | pmid:17142963 |
| Li Z et al. | The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. | 2006 | Cell Metab. | pmid:16679290 |
| Sternin E et al. | Changes in molecular order across the lamellar-to-inverted hexagonal phase transition depend on the position of the double-bond in mono-unsaturated phospholipid dispersions. | 2006 | Chem. Phys. Lipids | pmid:16574088 |
| Buzón V and Cladera J | Effect of cholesterol on the interaction of the HIV GP41 fusion peptide with model membranes. Importance of the membrane dipole potential. | 2006 | Biochemistry | pmid:17176099 |
| Mizushima N | [Methods for monitoring macroautophagy]. | 2006 | Tanpakushitsu Kakusan Koso | pmid:16922435 |
| Mudgil P et al. | Adsorption of lysozyme to phospholipid and meibomian lipid monolayer films. | 2006 | Colloids Surf B Biointerfaces | pmid:16530395 |
| Hirche F et al. | Effect of dietary methionine on plasma and liver cholesterol concentrations in rats and expression of hepatic genes involved in cholesterol metabolism. | 2006 | Br. J. Nutr. | pmid:16611377 |
| Kume H and Sasaki H | Ethanolamine modulates DNA synthesis through epidermal growth factor receptor in rat primary hepatocytes. | 2006 Jan-Feb | In Vitro Cell. Dev. Biol. Anim. | pmid:16618207 |
| Sawant RM et al. | "SMART" drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers. | 2006 Jul-Aug | Bioconjug. Chem. | pmid:16848401 |
| Dubielecka PM et al. | Mitoxantrone changes spectrin-aminophospholipid interactions. | 2006 May-Jun | Mol. Membr. Biol. | pmid:16785207 |
| Wen Z and Kim HY | Inhibition of phosphatidylserine biosynthesis in developing rat brain by maternal exposure to ethanol. | 2007 | J. Neurosci. Res. | pmid:17387686 |
| Song Y et al. | Rapid ambient mass spectrometric profiling of intact, untreated bacteria using desorption electrospray ionization. | 2007 | Chem. Commun. (Camb.) | pmid:17279261 |
| Sato T et al. | Poly(ethylene glycol)-conjugated phospholipids in aqueous micellar solutions: hydration, static structure, and interparticle interactions. | 2007 | J Phys Chem B | pmid:17286354 |
| Li D et al. | Seasonal variations of lipid content and composition in Perna viridis. | 2007 | Lipids | pmid:17576610 |
| Sanmarco M et al. | Antiphosphatidylethanolamine antibodies are associated with an increased odds ratio for thrombosis. A multicenter study with the participation of the European Forum on antiphospholipid antibodies. | 2007 | Thromb. Haemost. | pmid:17549297 |
| Tang N et al. | Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin. | 2007 | J. Natl. Cancer Inst. | pmid:17596572 |
| Epand RF et al. | Bacterial lipid composition and the antimicrobial efficacy of cationic steroid compounds (Ceragenins). | 2007 | Biochim. Biophys. Acta | pmid:17599802 |
| Murphy SC et al. | Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum. | 2007 | Blood | pmid:17526861 |
| Li D et al. | Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells. | 2007 | J. Pharmacol. Sci. | pmid:17895587 |
| Madeja Z et al. | New cationic polyprenyl derivative proposed as a lipofecting agent. | 2007 | Acta Biochim. Pol. | pmid:18066397 |
| Goss R et al. | Lipid dependence of diadinoxanthin solubilization and de-epoxidation in artificial membrane systems resembling the lipid composition of the natural thylakoid membrane. | 2007 | Biochim. Biophys. Acta | pmid:16843433 |
| Horibata Y and Hirabayashi Y | Identification and characterization of human ethanolaminephosphotransferase1. | 2007 | J. Lipid Res. | pmid:17132865 |
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